Information report for 84708
Gene Details
Functional Annotation
- Refseq: XP_024525979.1 — single-stranded DNA-binding protein WHY2, mitochondrial isoform X1
- Refseq: XP_024525980.1 — single-stranded DNA-binding protein WHY2, mitochondrial isoform X1
- Refseq: XP_024543888.1 — single-stranded DNA-binding protein WHY2, mitochondrial isoform X1
- Refseq: XP_024543889.1 — single-stranded DNA-binding protein WHY2, mitochondrial isoform X1
- TrEMBL: D8R3J9 — D8R3J9_SELML; Uncharacterized protein
- STRING: EFJ15931 — (Selaginella moellendorffii)
- STRING: EFJ33294 — (Selaginella moellendorffii)
- GO:0006281 — Biological Process — DNA repair
- GO:0032211 — Biological Process — negative regulation of telomere maintenance via telomerase
- GO:0045893 — Biological Process — positive regulation of transcription, DNA-templated
- GO:0045910 — Biological Process — negative regulation of DNA recombination
- GO:0009508 — Cellular Component — plastid chromosome
- GO:0009570 — Cellular Component — chloroplast stroma
- GO:0003697 — Molecular Function — single-stranded DNA binding
- GO:0003700 — Molecular Function — transcription factor activity, sequence-specific DNA binding
- GO:0003723 — Molecular Function — RNA binding
- GO:0042162 — Molecular Function — telomeric DNA binding
Family Introduction
- Members of the Whirly family of proteins are found throughout the plant kingdom and are predicted to share the ability to bind to single-stranded DNA. Arabidopsis and potato Whirly orthologs act as transcription factors that regulate defense gene expression; the Arabidopsis Whirly protein AtWhy1 contributes to both basal and specific defense responses. Analysis of the crystal structure of potato StWhy1 has provided insight into the DNA-binding mechanism of this family of proteins, their mode of action and possible autoregulation. There is evidence to suggest that Whirly proteins might play roles in processes other than defense responses and could function in the chloroplast as well as in the nucleus.
Literature and News
Gene Resources
- SuperFamily: SSF54447
- Gene3D: G3DSA:2.30.31.10
- Pfam: PF08536
- InterPro: IPR009044 IPR013742
Sequences
CDS Sequence:
- >84708|Selaginella_moellendorffii|Whirly|84708
ATGTCGAACCATGAGAAGATCACATGTGTGTCTTCTTCCCATCAGAATCTGGTGGAGAAGCTAATGCAACTCCAGGAGAGGTTCTCCCATCTCCAGGCTGCTAGGAAGGAAGGGAGGGTTGGTGATCACGCGGTTTTGGAAGCTCAGATCTCTCAGAATCTTCGTGAGTGGCAAGCTGAGCTCACCGCTCCTTCTCCTGAATCTTCTCTTCTGGGTGGGAGTATTAGCCAGTTCTCTGAGGAGATAGCTCGTTTGTTGAAACTAAACGACGAAGAGGATGATGCGACTAGTTCTTTGAAGGAACACGCTGCACCTAAGCCTGACGGTTTTGATCAAAGCTTGTGCCCCCCTCCAGAACATTTGGAATGGATAGATGAGGAGCCTTTTTGTCAAAGTCCTTTCCACGTTAATTTCTCCAGTGGTTTTGAGGAAGCTGTTAATAACACCCAACCGCATGACCAGCAACTCCACTTTGCATTTCAAGAGTTCGACCCAAGCATAAACACCGCTCCTGATTTCCATGTCCAGAGCAACTTGGATATAGCTTCTCAGTTGGATTACCATCTCTCAGAAGTGCGCCAGGAGTTCAACAACAGCCCTTCCATTAAGCTTGACGCGTCTGAGAACTACACTGACTTCACTACTCCACAAAGTGTCCGTGTGCCTCCTCCTCCTTCTGCCTTCTTGGGACCGAAGTGTGCACTATGGGACTGCACAAGGCCTGCTCACGGATCTGACTGGTACCTCGACTACTGCAGTGACTACCATGGGAACCTAGCTCTGAACGAAGATTCCCCTGGCGCAGCACCTGTTCTAAGACCAGGAGGCATTAGTTTGAAAGATAATCTCTTGATTGATGCTCTTCGTGCAAAGACTCTTGGTAAGAATGTTGGCATCCCAGAGTGTGAAGGAGCTGTTAACACAAAATGCCCATGGAACGCAGCAGAGCTATTTCATCTCGAGCTGGTTGAGGGTGAAACCATTAGAGAATGGCTCTTCTTCGACAAACCGAGAAGAGCATACGATAGTGGAAACCGAAAGCAGAGATCACTCCCAGATTACAGCGGAAGAGGGTGGCATGAATCAAGGAAACAGCTGATGAAAGAGCAAGAAGGGCAGAAGAGATCTTACTATATGGATCCACAACCTCCTGGTCTCTTCGAGTGGCATCTCTTCGAGTACCAGATCAACGAATCCGATGTGTGTGCATTATACAGACTAGAGCTCAAAGTAACAAATGGAAAGAAGAGTCCCAAGGGAAGAGTCGCGAAAGACCCTCTAGCTGATTTGCAGAAGAAGATGGAGAAGATGGGACATTTGACACCTGAGGTTGCTTCGGACAAACCCTCGCCTCCAACAAAAGGTCGTACAAAGTCTACCAAAGGAGTTAAGGTAGCAACTCAAGACACTCCGGTTCCTGCAACAGTAGCAAACGAGCCTGAGCCATCATCACATCAGTGA ATGGCAGCCCATGAGGCTACAGGTGAAAAACTATCGGCACTCGCCGTCAGCTTGTTAGCAGGTTCTTTTGTTTCAGAAACCCGACCAAGGCGAGTCTTTGCCGATCATGTGTTCTACAAAGGAAAGTGTGCGCTCAACATGCGACTCATCAAGCCGACTTTCAAGATATCAGATTCTGGAGACGCGATTCTCTCTCGAGAGGGGACTGTGATGCTGGAGTTTGCGCCATCCATCTCTCAGCGTCAGTACGACTGGGGAAAAAAGCAGGTACTTTTCGCTCTCTCTGTGAGCGAGCTCGGACAGATCCTTGCACTGACCCCGTCGGAATCTCTCGAGTTCTTTCACGACCCAAACATGGGAAAATCTGACGCTGGAATGGTGAGAAAGTCGCTCAAGATCGAACCCACCACGGACAGGAATGGATTCTTCTTCGGTTTAACTGTGGCAAACAAGGTGGAGAAAGCCGAGGCACGACTCAACATTCCAATCTCAAAGGGTGAATTTGCCATCATTCGCTCCGCGGCCAATTACGCTCTCCCTTATCTCATGGGCTGGCACTACGCCACTGAGGTGAACGGGATCGACGAGGCTGGCGCCAGTGGCGCCTCGGTCTCCGGCACCACCGCTCCCCGCAGCCTCGTCCAGCCTCCGTCCGACATCGATCCAGAGTGGGACAAGTAG GAGGTTGGGTTAGTCCAAATCCTTTCTTCGACAACGCCGCCTTCGAGCCACTGCTAGTGTTGTTAGCTGCTGATGATGACGACGACGACGACGCTGATGCTGATATGAACAATAACTTTGAGGTGGACAATGATGAAGACATGGAGCAAGATACGAACAGTATGAATAGAAACAACCATCACGAAGAATTATTTCATTATGAACATACTCAACAACAACAACCACCGCCACCACCATCACAAAGTTTGAGTCAGGGGAGTCATTCGGCGTCGGGCGTGGAAGAACATACCGGACGATGGACTAAAGAAGAACATGAAGCATTCTTACAAGGGTTGAAACTGTATGGTAAGGAGTGGAAGAAAGTCGCCGCTAAAGTTCGTACACGAACAGTCGTGCAAACACGTACCCATGCACAAAAGTATTTTCAGAAGTTACAGAAATCAATACAAGACAGTGCGACCAACAAACGGCGTGCTGGTGGTAATAATAGTCATAATGCGGAATACGGAGATGATATGCGAGATGGACAATATGCGCATGATGACGAAACGCAACGGATGATAGCAATAATGAACAGTAACAATTCACTCAATGATGATGACAATGAGGACGAGGATGGATTTACCAGTACTGCGGTATTTTCAACGGCTAGTACACGAGGACGGGGCAGCAGTACGCGTGGACGTGGTGGTCGACGTGGTGCAGCAGCTAACAACACTAGTAGCGGCTCGAAGGCGGCTTTGTCGAAGAAAGGGTTTGGACTAACCCAACCTCAACCATTATTACCACCGCCACCCGTAACTGCAATGAACATTATGAAGAACAATATTGGGGCAGCATCGATCAACCAGACACCATCTCATCAATTACGTAGGGGTAGTACAGCAACATTAAATGCTGCACAAGTTATATCTACTCTTAGTTCCGCCAAGACGGGCGACAACAACACGACGAAACAACAAACAGCCGGAAGCATCATTCATTCAACACCATCTCGGGTTGACCATAAAAATTATTTTACAAGTAATAATAATACTACATTATCATCATCGTCCAACATGAAAATTACAGCACCAGATCCATCAAGAATGGGACGACATTATGCATTCCCAGAACCTTCTCCGGCAGCGAC GATGACGAAGAAATTTACGAAGTACTCGGAGACTTATTCCTCGACGATGAACCTGAAGGAACTGCAGACGAAAACTCACGTGCAGACGTCGAACAACACGAAGTTGATCGAAATCTCGAAAATTCTGTCGTCGACACCCAAGGTGGAAATCGTGAACAAGTCAACAACTCTCAAGAAGATAACCGTCCAATGTGCAGTCTGTGCGGAATTCATTTCACCAGAAATTGGAACCTGAAACGTCACAACGACAAGTTTCATCGGAAATCCAACAACTGCCTGATCTGCAAAAAACCGTACCACTTTGTCGACAACCTCATCCACCACGTCCATGTTCATCACAAAGATGCTCACGACGAATTTCAACCTAACCAAGACAATTCCTTCTCGTGCACGTATTGTGGTGACCGATCGACTACATTGGGACAACTCTTTTGGCATTTGCAAGAAAACCACGAAGTGCAAAACCACTTGACGTGA
Protein Sequence:
- >84708|Selaginella_moellendorffii|Whirly|84708
MAAHEATGEKLSALAVSLLAGSFVSETRPRRVFADHVFYKGKCALNMRLIKPTFKISDSGDAILSREGTVMLEFAPSISQRQYDWGKKQVLFALSVSELGQILALTPSESLEFFHDPNMGKSDAGMVRKSLKIEPTTDRNGFFFGLTVANKVEKAEARLNIPISKGEFAIIRSAANYALPYLMGWHYATEVNGIDEAGASGASVSGTTAPRSLVQPPSDIDPEWDK*