Gene Details:

• Gene ID: HL.SW.v1.0.G008081.1
• Gene Family: Trihelix Family
• Description: Trihelix Family protein
• Species: Humulus lupulus
• Source: Trihelix family gene from PlantTFDB

Protein Features:

• Pfam:  PF13837
• PROSITE profile:  PS50090
• InterPro:  IPR017877

Annotation Proteins:

• Refseq:  XP_010103346.1  — uncharacterized protein LOC21385857
• TrEMBL:  A0A2P5C4X0  — A0A2P5C4X0_PARAD; Sequence-specific DNA binding transcription factor
• STRING:  XP_010103346.1  — (Morus notabilis)

Gene Ontology:

• GO:0010629  — Biological Process — negative regulation of gene expression
• GO:1900037  — Biological Process — regulation of cellular response to hypoxia
• GO:0005634  — Cellular Component — nucleus

Family Introduction:

• GT factors constitute a plant-specific transcription factor family with a DNA-binding domain that binds GT elements. The DNA-binding domain of GT factor, rich in basic and acidic amino acids and proline and glutamine residues, features a typical trihelix (helix-loop-helix-loop-helix) structure that determines the specific binding of GT elements; thus GT factors are also called trihelix transcription factors. GT elements are highly degenerate cis-elements with A/T-rich core sequences (Villain et al. 1996; Wang et al. 2004). Interaction between GT factors and GT elements has been implicated in the complex transcriptional regulation of many plant genes.

Literature:

• Systematic analysis of GT factor family of rice reveals a novel subfamily involved in stress responses.   DOI:  10.1007/s00438-009-0507-x ;  PMID:  20039179

Sequences: