Gene Details:

• Gene ID: AT5G28300.1
• Gene Name: AtGT2L, GT2L, T8M17.70
• Gene Family: Trihelix Family
• Description: Trihelix Family protein
• Species: Arabidopsis thaliana
• Source: Trihelix family gene from PlantTFDB

Protein Features:

• Pfam:  PF13837
• PROSITE profile:  PS50090
• InterPro:  IPR017877

Annotation Proteins:

• Refseq:  NP_568506.2  — Duplicated homeodomain-like superfamily protein
• Swissprot:  Q8H181  — GTL2_ARATH; Trihelix transcription factor GTL2
• TrEMBL:  A0A178UB25  — A0A178UB25_ARATH; GT2L
• STRING:  AT5G28300.1  — (Arabidopsis thaliana)

Gene Ontology:

• GO:0045893  — Biological Process — positive regulation of transcription, DNA-templated
• GO:0005634  — Cellular Component — nucleus
• GO:0001158  — Molecular Function — enhancer sequence-specific DNA binding
• GO:0003700  — Molecular Function — transcription factor activity, sequence-specific DNA binding
• GO:0005516  — Molecular Function — calmodulin binding

Family Introduction:

• GT factors constitute a plant-specific transcription factor family with a DNA-binding domain that binds GT elements. The DNA-binding domain of GT factor, rich in basic and acidic amino acids and proline and glutamine residues, features a typical trihelix (helix-loop-helix-loop-helix) structure that determines the specific binding of GT elements; thus GT factors are also called trihelix transcription factors. GT elements are highly degenerate cis-elements with A/T-rich core sequences (Villain et al. 1996; Wang et al. 2004). Interaction between GT factors and GT elements has been implicated in the complex transcriptional regulation of many plant genes.

Literature:

• Systematic analysis of GT factor family of rice reveals a novel subfamily involved in stress responses.   DOI:  10.1007/s00438-009-0507-x ;  PMID:  20039179

Sequences: