Gene Details:

• Gene ID: AT2G38250.1
• Gene Name: F16M14.18, GT1L, GT3B, GT-3B
• Gene Family: Trihelix Family
• Description: Trihelix Family protein
• Species: Arabidopsis thaliana
• Source: Trihelix family gene from PlantTFDB

Protein Features:

• Pfam:  PF13837
• PROSITE profile:  PS50090
• InterPro:  IPR017877

Annotation Proteins:

• Refseq:  NP_181360.1  — Homeodomain-like superfamily protein
• Swissprot:  O80450  — TGT3B_ARATH; Trihelix transcription factor GT-3b
• TrEMBL:  A0A178VPR5  — A0A178VPR5_ARATH; Uncharacterized protein
• STRING:  AT2G38250.1  — (Arabidopsis thaliana)

Gene Ontology:

• GO:0006355  — Biological Process — regulation of transcription, DNA-templated
• GO:0005730  — Cellular Component — nucleolus
• GO:0016592  — Cellular Component — mediator complex
• GO:0003677  — Molecular Function — DNA binding
• GO:0003700  — Molecular Function — transcription factor activity, sequence-specific DNA binding
• GO:0005515  — Molecular Function — protein binding

Family Introduction:

• GT factors constitute a plant-specific transcription factor family with a DNA-binding domain that binds GT elements. The DNA-binding domain of GT factor, rich in basic and acidic amino acids and proline and glutamine residues, features a typical trihelix (helix-loop-helix-loop-helix) structure that determines the specific binding of GT elements; thus GT factors are also called trihelix transcription factors. GT elements are highly degenerate cis-elements with A/T-rich core sequences (Villain et al. 1996; Wang et al. 2004). Interaction between GT factors and GT elements has been implicated in the complex transcriptional regulation of many plant genes.

Literature:

• Systematic analysis of GT factor family of rice reveals a novel subfamily involved in stress responses.   DOI:  10.1007/s00438-009-0507-x ;  PMID:  20039179

Sequences: