Gene Details:

• Gene ID: AT2G37120.1
• Gene Name: S1FA2, T2N18.12
• Gene Family: S1Fa-like Family
• Description: S1Fa-like Family protein
• Species: Arabidopsis thaliana
• Source: S1Fa-like family gene from PlantTFDB

Protein Features:

• Pfam:  PF03094
• Pfam:  PF04689
• InterPro:  IPR004326    IPR006779

Annotation Proteins:

• Refseq:  NP_565859.1  — S1FA-like DNA-binding protein
• Swissprot:  Q42337  — S1FA2_ARATH; DNA-binding protein S1FA2
• TrEMBL:  A0A178VX36  — A0A178VX36_ARATH; Uncharacterized protein
• STRING:  AT2G37120.1  — (Arabidopsis thaliana)

Gene Ontology:

• GO:0006355  — Biological Process — regulation of transcription, DNA-templated
• GO:0005634  — Cellular Component — nucleus
• GO:0003677  — Molecular Function — DNA binding

Family Introduction:

• A cDNA encoding a specific binding activity for the tissue-specific negative cis-element S1F binding site of spinach rps1 was isolated from a spinach cDNA expression library. This cDNA of 0.7 kb encodes an unusual small peptide of only 70 amino acids, with a basic domain which contains a nuclear localization signal and a putative DNA binding helix. This protein, named S1Fa, is highly conserved between dicotyledonous and monocotyledonous plants and may represent a novel class of DNA binding proteins. The corresponding mRNA is accumulated more in roots and in etiolated seedlings than in green leaves. This expression pattern is correlated with the tissue-specific function of the S1F binding site which represses the rps1 promoter preferentially in roots and in etiolated plants.

Literature:

• Molecular cloning of a small DNA binding protein with specificity for a tissue-specific negative element within the rps1 promoter.   DOI:  10.1093/nar/23.7.1165 ;  PMID:  7739894

Sequences: