Gene Details:

• Gene ID: 462845084
• Gene Family: NF-YB Family
• Description: NF-YB Family protein
• Species: Eragrostis tef
• Source: NF-YB family gene from PlantTFDB

Protein Features:

• Gene3D:  G3DSA:1.10.20.10
• SuperFamily:  SSF47113
• Pfam:  PF00808
• PRINTS:  PR00615
• PROSITE pattern:  PS00685
• InterPro:  IPR009072    IPR003958    IPR003956

Annotation Proteins:

• Refseq:  XP_015635864.1  — nuclear transcription factor Y subunit B-1
• Refseq:  XP_015635872.1  — nuclear transcription factor Y subunit B-1
• Swissprot:  Q75IZ7  — NFYB8_ORYSJ; Nuclear transcription factor Y subunit B-8
• TrEMBL:  A0A0D3EYD4  — A0A0D3EYD4_9ORYZ; Uncharacterized protein
• TrEMBL:  A0A0E0N7B5  — A0A0E0N7B5_ORYRU; Uncharacterized protein
• TrEMBL:  I1NUZ7  — I1NUZ7_ORYGL; Uncharacterized protein
• TrEMBL:  Q942Y5  — Q942Y5_ORYSJ; HAP3 subunit of HAP complex
• STRING:  ORUFI01G46550.1  — (Oryza rufipogon)
• STRING:  OS01T0935200-01  — (Oryza sativa)
• STRING:  ORGLA01G0368700.1  — (Oryza glaberrima)
• STRING:  OBART01G43130.1  — (Oryza barthii)

Gene Ontology:

• GO:0046982  — Molecular Function — protein heterodimerization activity

Family Introduction:

• NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).
• As with NF-YA, NF-YB and NF-YC families have well-described subunit interaction and DNA-binding domains ( Kim et al., 1996; Sinha et al., 1996; McNabb et al., 1997; Romier et al., 2003). The conserved regions of NF-YB and NF-YC have structural and amino acid homology to histone fold motifs. Specifically, NF-YB is related to the histone fold motifs of H2B histones, while NF-YC subunits are related to H2A histones (Mantovani, 1999).

Literature:

• Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.   DOI:  10.1104/pp.108.130591 ;  PMID:  19019982

Sequences: