Information report for GSVIVT01015120001
Gene Details
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Functional Annotation
- Refseq: XP_002278441.2 — PREDICTED: nuclear transcription factor Y subunit A-3 isoform X1
- Refseq: XP_010656137.1 — PREDICTED: nuclear transcription factor Y subunit A-3 isoform X1
- Refseq: XP_010656139.1 — PREDICTED: nuclear transcription factor Y subunit A-3 isoform X1
- Refseq: XP_010656140.1 — PREDICTED: nuclear transcription factor Y subunit A-3 isoform X1
- Refseq: XP_010656142.1 — PREDICTED: nuclear transcription factor Y subunit A-3 isoform X1
- Refseq: XP_010656144.1 — PREDICTED: nuclear transcription factor Y subunit A-3 isoform X1
- Refseq: XP_010656145.1 — PREDICTED: nuclear transcription factor Y subunit A-3 isoform X1
- Swissprot: Q93ZH2 — NFYA3_ARATH; Nuclear transcription factor Y subunit A-3
- TrEMBL: A0A438E8D0 — A0A438E8D0_VITVI; Nuclear transcription factor Y subunit A-3
- STRING: VIT_11s0016g01480.t01 — (Vitis vinifera)
- GO:0006355 — Biological Process — regulation of transcription, DNA-templated
- GO:0016021 — Cellular Component — integral component of membrane
- GO:0003700 — Molecular Function — transcription factor activity, sequence-specific DNA binding
Family Introduction
- NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).
- NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.
Literature and News
Gene Resources
Homologs
- Gossypium arboreum: Cotton_A_03153_BGI-A2_v1.0
- Gossypium hirsutum: Gh_A13G1701
- Manihot esculenta: Manes.16G097900.2.p, Manes.16G097900.1.p
- Nicotiana tabacum: XP_016445413.1
- Populus trichocarpa: Potri.006G145100.4, Potri.006G145100.3, Potri.006G145100.2, Potri.006G145100.1, Potri.018G064700.1, Potri.018G064700.2
- Prunus mume: XP_008242196.1, XP_016651810.1, XP_008242197.1, XP_016651811.1
- Prunus persica: Prupe.7G203500.1.p
- Ricinus communis: 29912.m005288
Sequences
CDS Sequence:
- >GSVIVT01015120001|Vitis_vinifera|NF-YA|GSVIVT01015120001
ATGCCCCATTTCACTGTTAATTGCCAAGCTTGGTGGAATTCAAATGAACAGCAGCTTCCAGAGTCTTTTTCAAAAAATCTAAGCTTGAAAGTTGAATCTCCGCCCCAACTCTATCAAAACATGAAGCAATTAGGTCTTCAACTACAAGACCAGGACTCATCCTCAAGTCAATCAACTGGTCAGTCTCACCAAGAAGTGTCTGCTATCGGAAGGACCAATTCTCAAGATCAATGTATTTCATCTGAATCTGTTCATGGTGAAAGTTGCGAGAAGCGTGTGGAAGGTCAAAGTCAAATGAAGCCAGTTTTCTTTATGGCTAATCCAGATGTTGTCTTCAATCCTTCACAAGTTGACTATGGCCATTCTGTGACTCATGTTGCATATCCTTATGCTGATCCTTACCATGGGGGGTTAGTGGCTGCATATGGTCCACATGCTGTTATTCAGCCCCAGCTGGTGGGGATAGCACCTACCAGAGTCCCACTGCCCTTTGATATTGCAGAGGATGGACCTATTTTTGTCAATGCAAAACAGTATCATGGAATTCTCAGGAGGAGGCAGTCACGAGCAAAGATGGAGGCCCAGAACAAACTTGTCAAAGCCCGAAAGCCATATCTGCACGAGTCTCGGCATCTTCATGCCCTAAATAGGGTTAGAGGATCTGGTGGACGCTTCCTCAGCACGAAAAAGCTCCAAGAACCCGACTCAACTTCCAATGCTGGCTGTCATAGTTCTGATACTGGCAAATTTGTTGCTTCAACTACATCCAGCTCTGATGTCACCAGTGTCTCTAACAGTGATGTCCTTTTCAGGCAGCCGGAGCACAGGTTCTCAGGCATGTCTCCCCACATGGGTGGAGCCATGCAAGGTGGTGGCGGTGGGACTTATGGGCAATGGAGTCCTGCTCCTGGTTGTCCGGTGAGAAGTCGATAG
Protein Sequence:
- >GSVIVT01015120001|Vitis_vinifera|NF-YA|GSVIVT01015120001
MPHFTVNCQAWWNSNEQQLPESFSKNLSLKVESPPQLYQNMKQLGLQLQDQDSSSSQSTGQSHQEVSAIGRTNSQDQCISSESVHGESCEKRVEGQSQMKPVFFMANPDVVFNPSQVDYGHSVTHVAYPYADPYHGGLVAAYGPHAVIQPQLVGIAPTRVPLPFDIAEDGPIFVNAKQYHGILRRRQSRAKMEAQNKLVKARKPYLHESRHLHALNRVRGSGGRFLSTKKLQEPDSTSNAGCHSSDTGKFVASTTSSSDVTSVSNSDVLFRQPEHRFSGMSPHMGGAMQGGGGGTYGQWSPAPGCPVRSR*