Gene Details:

• Gene ID: GSBRNA2T00104205001
• Gene Name: GSBRNA2T00104205001, LOC106372343
• Gene Family: NF-X1 Family
• Description: NF-X1 Family protein
• Species: Brassica napus
• Source: NF-YA family gene from PlantTFDB

Protein Features:

• SMART:  SM00521
• PROSITE profile:  PS51152
• Pfam:  PF02045
• PRINTS:  PR00616
• PROSITE pattern:  PS00686
• InterPro:  IPR001289    IPR018362

Annotation Proteins:

• Refseq:  XP_013667993.1  — nuclear transcription factor Y subunit A-1
• Refseq:  XP_013667994.1  — nuclear transcription factor Y subunit A-1
• Refseq:  XP_022565883.1  — nuclear transcription factor Y subunit A-1
• Swissprot:  Q9LXV5  — NFYA1_ARATH; Nuclear transcription factor Y subunit A-1
• TrEMBL:  W6D6R0  — W6D6R0_BRANA; Transcription factor subunit NF-YA1A
• STRING:  Bo9g169310.1  — (Brassica oleracea)

Gene Ontology:

• GO:0006355  — Biological Process — regulation of transcription, DNA-templated
• GO:0010262  — Biological Process — somatic embryogenesis
• GO:0048510  — Biological Process — regulation of timing of transition from vegetative to reproductive phase
• GO:0055046  — Biological Process — microgametogenesis
• GO:0016602  — Cellular Component — CCAAT-binding factor complex
• GO:0003677  — Molecular Function — DNA binding
• GO:0003700  — Molecular Function — transcription factor activity, sequence-specific DNA binding

Family Introduction:

• NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).
• NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.

Literature:

• Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.   DOI:  10.1104/pp.108.130591 ;  PMID:  19019982

Sequences: