Gene Details:

• Gene ID: fgenesh3_pg.C_scaffold_15000025
• Gene Name: CHLNCDRAFT_53340
• Gene Family: NF-X1 Family
• Description: NF-X1 Family protein
• Species: Chlorella variabilis NC64A
• Source: NF-YA family gene from PlantTFDB

Protein Features:

• SMART:  SM00521
• PROSITE profile:  PS51152
• Pfam:  PF02045
• PRINTS:  PR00616
• PROSITE pattern:  PS00686
• InterPro:  IPR001289    IPR018362

Annotation Proteins:

• Refseq:  XP_005845959.1  — hypothetical protein CHLNCDRAFT_53340
• TrEMBL:  E1ZJG5  — E1ZJG5_CHLVA; Uncharacterized protein
• STRING:  XP_005845959.1  — (Chlorella variabilis)

Gene Ontology:

• GO:0005975  — Biological Process — carbohydrate metabolic process
• GO:0006355  — Biological Process — regulation of transcription, DNA-templated
• GO:0010262  — Biological Process — somatic embryogenesis
• GO:0003700  — Molecular Function — transcription factor activity, sequence-specific DNA binding
• GO:0004553  — Molecular Function — hydrolase activity, hydrolyzing O-glycosyl compounds
• GO:0005515  — Molecular Function — protein binding

Family Introduction:

• NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).
• NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.

Literature:

• Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.   DOI:  10.1104/pp.108.130591 ;  PMID:  19019982

Sequences: