Information report for Tp57577_TGAC_v2_mRNA4278
Gene Details
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Functional Annotation
- Refseq: XP_003596969.1 — transcription factor MYB101
- TrEMBL: A0A2K3KZF1 — A0A2K3KZF1_TRIPR; Transcription factor
- STRING: AES67220 — (Medicago truncatula)
- GO:0003677 — Molecular Function — DNA binding
Family Introduction
- MYB factors represent a family of proteins that include the conserved MYB DNA-binding domain.The first MYB gene identified was the ‘oncogene’ v-Myb derived from the avian myeloblastosis virus . Evidence obtained from sequence comparisons indicates that v-Myb may have originated from a vertebrate gene, which mutated once it became part of the virus. Many vertebrates contain three genes related to v-Myb c-Myb, A-Myb and B-Myb and other similar genes have been identified in insects, plants, fungi and slime moulds. The encoded proteins are crucial to the control of proliferation and differentiation in a number of cell types, and share the conserved MYB DNA-binding domain. This domain generally comprises up to three imperfect repeats, each forming a helix-turn-helix structure of about 53 amino acids. Three regularly spaced tryptophan residues, which form a tryptophan cluster in the three-dimensional helix-turn-helix structure, are characteristic of a MYB repeat. The three repeats in c-Myb are referred to as R1, R2 and R3; and repeats from other MYB proteins are categorised according to their similarity to either R1, R2 or R3.
- In contrast to animals, plants contain a MYB-protein subfamily that is characterised by the R2R3-type MYB domain. MYB proteins can be classified into three subfamilies depending on the number of adjacent repeats in the MYB domain (one, two or three). We refer to MYB-like proteins with one repeat as ‘MYB1R factors’, with two as ‘R2R3-type MYB’ factors, and with three repeats as ‘MYB3R’ factors.
Literature and News
Gene Resources
Homologs
- Cajanus cajan: C.cajan_35310
- Cicer arietinum: XP_004487418.1
- Citrullus lanatus: Cla007663
- Citrus sinensis: orange1.1g039708m
- Cucumis melo: MELO3C018820P1
- Cucumis sativus: Cucsa.148580.1
- Glycine max: Glyma.12G193300.1.p, Glyma.13G309200.1.p
- Juglans regia: WALNUT_00027900-RA
- Manihot esculenta: Manes.S051400.1.p
- Medicago truncatula: Medtr2g088170.1
- Populus trichocarpa: Potri.002G228700.1
- Prunus persica: Prupe.3G216600.1.p
- Pyrus bretschneideri: Pbr018111.1
- Ricinus communis: 29823.m000215
- Ziziphus jujuba: XP_015881129.1
Sequences
CDS Sequence:
- >Tp57577_TGAC_v2_mRNA4278|Trifolium_pratense|MYB|Tp57577_TGAC_v2_mRNA4278
ATGGCTAGAATAATAATCTCCAACAACAATACTAATAACAATGTTGAGGTGGACATTGAGTCATCAAAAGATGATGTTGATGCAAAAACTGGCATGAAGAAGGGACCATGGACCCCACAAGAAGATATGATTTTGATAGAGTACGTGAATAAGCATTGTGAAGGGAATTGGAATTCTGTTCAGAAAAATTCAGGATTGTTAAGGTGTGGAAAAAGCTGCAGACTTAGATGGGCCAATCATTTAAGGCCCAATCTTAAGAAAGGTTCATTTTCTGAAGATGAAGAAAAAATCATCATTGAACTTCATGCTAAGCTTGGAAACAAATGGGCTAGAATGGCTGCTCAGGTATTATATTTTACTATAAATTATATTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTGCATAATTTTTTTTTTATTATTTTTTTTTTGCATAAAATCTCATTGCCAGGGAGAACGGACAATGAAATAAAAAACTTTTGGAACACGAGAATGAAAAGGCGTCAGAGAGCAGGATTACCTCTTTACCCTCCTGAAGTCCAAGCAGAAGCTATTGCATACAATAATCATCTAATGAAAGAATATCACCATACTATTGATGAACCTTTATCTTCTTCATCACCATCATTTTCTTTACTCTTATCTTCATGTTACCCTAAGAATATTGATAATGATCAAAACAATCATGATTATAATCCTATGCAAAACAACTCTGATTCTTCTAATCATTACACCAATCCATCTCCACAATTCAACTTTTCCAATGATCATGAAAATTTAGAGATCAATGAAACTCATGCATTGCCAAATTCACCTTCACTTTCTCCTTATCCATCTTCATCATCAAATCTTATCAACCATAGTTTTGGTAATCCAAATGATTCACATGAGTACCAATATTCTGAAAATTTGAGCTATGATCAACATGGATTCAATGCAAGGTCTTTGTGTGATTCTGAAACTCCTGTTTCATCTTATGCTAGTGGTGTTGATGGTTTGATGGGAAATTCAAACATGGTTAATGATTGCTATGAAGATCATGCACCACTATCTCCTAAAGGAAACAATAGTGGACTTTTGGATGATCTTGTGATGGAAGGTAGAAATATTTCATGCAATGATAAGGCTAGGAGTGAGGATTCAACATTTAGGGGGAATGAATCTTATAAGAGGAAAAGAATGGAGGGTGAGGAATATAATGAAGAAAGAGACATCATTCCTTTGATGAAGAAGAGGATTGTTGATGAGACTCAGAAGAAAGATTTTAGCTCTTCTCAATTGCCAACAGGGAAGAAACCAATTGAAGAGGATCCATTAGCAGGGATGAATTCAGTGTATGATGATGACTTGGATTGCTTGCTCAACAATTTTCCCTCAGAAATACCAATGCCTGAATGGTATTGTAGAGGAAAAAGCCAATCTTTGGGACTTGAAACTCAAACTGATCATGCTTCTTCATCATCTGTCCCCAACAATCAAGAATTTGCTTGGACTCTTGGATCAACTTGGAGCAACATGCCTGGAATATGTTAA
Protein Sequence:
- >Tp57577_TGAC_v2_mRNA4278|Trifolium_pratense|MYB|Tp57577_TGAC_v2_mRNA4278
MARIIISNNNTNNNVEVDIESSKDDVDAKTGMKKGPWTPQEDMILIEYVNKHCEGNWNSVQKNSGLLRCGKSCRLRWANHLRPNLKKGSFSEDEEKIIIELHAKLGNKWARMAAQVLYFTINYIXXXXXXXXXXXXXXXFLHNFFFIIFFLHKISLPGRTDNEIKNFWNTRMKRRQRAGLPLYPPEVQAEAIAYNNHLMKEYHHTIDEPLSSSSPSFSLLLSSCYPKNIDNDQNNHDYNPMQNNSDSSNHYTNPSPQFNFSNDHENLEINETHALPNSPSLSPYPSSSSNLINHSFGNPNDSHEYQYSENLSYDQHGFNARSLCDSETPVSSYASGVDGLMGNSNMVNDCYEDHAPLSPKGNNSGLLDDLVMEGRNISCNDKARSEDSTFRGNESYKRKRMEGEEYNEERDIIPLMKKRIVDETQKKDFSSSQLPTGKKPIEEDPLAGMNSVYDDDLDCLLNNFPSEIPMPEWYCRGKSQSLGLETQTDHASSSSVPNNQEFAWTLGSTWSNMPGIC*