Gene Details:

  • Gene ID: AT1G35515.1
  • Gene Name: HOS10, MYB8
  • Gene Family: MYB Family
  • Description: MYB Family protein
  • Species: Arabidopsis thaliana
  • Source: MYB family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  NP_849749.1  — high response to osmotic stress 10
  • Swissprot:  Q9SDS8  — MYB8_ARATH; Transcription factor MYB8
  • TrEMBL:  D7KLV4  — D7KLV4_ARALL; Uncharacterized protein
  • STRING:  AT1G35515.1  — (Arabidopsis thaliana)

Gene Ontology:

  • GO:0006357  — Biological Process — regulation of transcription from RNA polymerase II promoter
  • GO:0009631  — Biological Process — cold acclimation
  • GO:0009651  — Biological Process — response to salt stress
  • GO:0009751  — Biological Process — response to salicylic acid
  • GO:0030154  — Biological Process — cell differentiation
  • GO:0005634  — Cellular Component — nucleus
  • GO:0000981  — Molecular Function — RNA polymerase II transcription factor activity, sequence-specific DNA binding
  • GO:0001135  — Molecular Function — transcription factor activity, RNA polymerase II transcription factor recruiting
  • GO:0043565  — Molecular Function — sequence-specific DNA binding
  • GO:0044212  — Molecular Function — transcription regulatory region DNA binding

Family Introduction:

  • MYB factors represent a family of proteins that include the conserved MYB DNA-binding domain.The first MYB gene identified was the ‘oncogene’ v-Myb derived from the avian myeloblastosis virus . Evidence obtained from sequence comparisons indicates that v-Myb may have originated from a vertebrate gene, which mutated once it became part of the virus. Many vertebrates contain three genes related to v-Myb c-Myb, A-Myb and B-Myb and other similar genes have been identified in insects, plants, fungi and slime moulds. The encoded proteins are crucial to the control of proliferation and differentiation in a number of cell types, and share the conserved MYB DNA-binding domain. This domain generally comprises up to three imperfect repeats, each forming a helix-turn-helix structure of about 53 amino acids. Three regularly spaced tryptophan residues, which form a tryptophan cluster in the three-dimensional helix-turn-helix structure, are characteristic of a MYB repeat. The three repeats in c-Myb are referred to as R1, R2 and R3; and repeats from other MYB proteins are categorised according to their similarity to either R1, R2 or R3.
  • In contrast to animals, plants contain a MYB-protein subfamily that is characterised by the R2R3-type MYB domain. MYB proteins can be classified into three subfamilies depending on the number of adjacent repeats in the MYB domain (one, two or three). We refer to MYB-like proteins with one repeat as ‘MYB1R factors’, with two as ‘R2R3-type MYB’ factors, and with three repeats as ‘MYB3R’ factors.

Literature:

Sequences:

CDS Sequence:
  • >AT1G35515.1|Arabidopsis_thaliana|MYB|AT1G35515.1
    ATGGGAAGATCACCATGTTGTGAAAAGGCTCACATGAACAAAGGAGCATGGACTAAAGAAGAAGATCAACGTCTTATTGATTATATACGTAATCATGGTGAAGGCTCTTGGCGTTCTCTTCCTAAATCCGTTGGGTTGTTGCGTTGTGGAAAAAGTTGTAGATTAAGATGGATTAATTACCTTCGTCCTGATCTTAAACGTGGAAATTTCACTGATGGTGAAGAGCAAATCATTGTCAAACTTCATAGTTTATTTGGCAACAAATGGTCTTTGATTGCTGGGAAATTACCGGGAAGAACCGATAATGAGATTAAAAATTATTGGAACACTCATATAAAAAGGAAGCTTCTTAACCGTGGTATTGACCCAAAAACTCACGGTTCGATCATCGAGCCTAAAACGACATCGTTTCATCCCCGAAATGAAGATTTGAAGTCCACGTTTCCCGGTTCTGTTAAACTAAAGATGGAGACTTCTTGTGAAAACTGTGCTTCTACGAGCGGTACGACTACGGACGAGGATTTACGGTTAAGTGTTGATTGTGATTACAGATATGATCATCTGGACAAGGAGCTAAACTTGGACCTAACACTCGGGTACAGTCCGACTCGATTTGTCGGGGTCGGATCTTGTTACTAG
Protein Sequence:
  • >AT1G35515.1|Arabidopsis_thaliana|MYB|AT1G35515.1
    MGRSPCCEKAHMNKGAWTKEEDQRLIDYIRNHGEGSWRSLPKSVGLLRCGKSCRLRWINYLRPDLKRGNFTDGEEQIIVKLHSLFGNKWSLIAGKLPGRTDNEIKNYWNTHIKRKLLNRGIDPKTHGSIIEPKTTSFHPRNEDLKSTFPGSVKLKMETSCENCASTSGTTTDEDLRLSVDCDYRYDHLDKELNLDLTLGYSPTRFVGVGSCY