Gene Details:

  • Gene ID: AA40G00160
  • Gene Family: MYB Family
  • Description: MYB Family protein
  • Species: Aethionema arabicum
  • Source: MYB family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  XP_013596421.1  — PREDICTED: transcription factor MYB86-like
  • Swissprot:  Q8LPH6  — MYB86_ARATH; Transcription factor MYB86
  • TrEMBL:  A0A087G979  — A0A087G979_ARAAL; Uncharacterized protein
  • STRING:  A0A087G979  — (Arabis alpina)

Gene Ontology:

  • GO:0003677  — Molecular Function — DNA binding

Family Introduction:

  • MYB factors represent a family of proteins that include the conserved MYB DNA-binding domain.The first MYB gene identified was the ‘oncogene’ v-Myb derived from the avian myeloblastosis virus . Evidence obtained from sequence comparisons indicates that v-Myb may have originated from a vertebrate gene, which mutated once it became part of the virus. Many vertebrates contain three genes related to v-Myb c-Myb, A-Myb and B-Myb and other similar genes have been identified in insects, plants, fungi and slime moulds. The encoded proteins are crucial to the control of proliferation and differentiation in a number of cell types, and share the conserved MYB DNA-binding domain. This domain generally comprises up to three imperfect repeats, each forming a helix-turn-helix structure of about 53 amino acids. Three regularly spaced tryptophan residues, which form a tryptophan cluster in the three-dimensional helix-turn-helix structure, are characteristic of a MYB repeat. The three repeats in c-Myb are referred to as R1, R2 and R3; and repeats from other MYB proteins are categorised according to their similarity to either R1, R2 or R3.
  • In contrast to animals, plants contain a MYB-protein subfamily that is characterised by the R2R3-type MYB domain. MYB proteins can be classified into three subfamilies depending on the number of adjacent repeats in the MYB domain (one, two or three). We refer to MYB-like proteins with one repeat as ‘MYB1R factors’, with two as ‘R2R3-type MYB’ factors, and with three repeats as ‘MYB3R’ factors.

Literature:

Sequences:

CDS Sequence:
  • >AA40G00160|Aethionema_arabicum|MYB|AA40G00160
    ATGGGAAGACATTCTTGTTGTTTTAAGCAAAAACTAAGGAAAGGTCTTTGGTCTCCTGAAGAAGATGAAAAACTTCTTAATTACATCACTAGACATGGCCATGGCTGCTGGAGTTCTGTCCCTAAACTCGCAGGGTTACAAAGATGTGGAAAAAGTTGTAGACTTCGATGGATAAATTATCTAAGACCCGATTTAAAAAGGGGAGCTTTTTCTCAAGAAGAAGAAAGTTTAATCATCGAACTTCATGCCGCGTTAGGCAACAGGTGGTCACAAATTGCGACTCGATTACCAGGAAGAACAGATAACGAAATAAAGAATTTTTGGAATTCATGTCTTAAGAAGAAACTAAGAAGAAAAGGCATTGATCCAACAACACATAAACCTCTAATAAATGATCTTCATCAATGTCTTGAAACCCATGACATCATAGATCAAAAGCTGACGTCATCACAAATTTTAAAGTCAACGGCTTCAATAAACCAATTACAAGATACAACAACAACATGGTGTTTTCCAACAATGATGACTACTAATCAAAACGCTGCGTTTTGCAACACTACTACAAATCCAACGGTTTCAGATCAGATTGTATCTCTAATCTCTTCAATGTCCACGTCAGCATCTCCAACACCAAACTACAATCTTGTTCCAAACAATTGGGAACTCAATTACAACAATTCAGTTCCATGTCAGAGTATTTACAGCACTTTTTTTGGTAATCATTACACAGATCAAACTACTCAAATTATGAACAATAATAATACTAATAATAATCAAGAAATGAAATCTTGGGGATTAGAGATTCTTGATCAATATACAGATCAATCTTGTTTAGAGATTGAAGTAAAGCCAGAGATAAATAAATTCTACTGGAAATCGTCGTCGTCGTCGCCGCCAAATCAATTAGATGTTACAGAACCGATTCTGAAATTTGTTGGACCTCAAGTTCAAAATGTATTTAAATTT
Protein Sequence:
  • >AA40G00160|Aethionema_arabicum|MYB|AA40G00160
    MGRHSCCFKQKLRKGLWSPEEDEKLLNYITRHGHGCWSSVPKLAGLQRCGKSCRLRWINYLRPDLKRGAFSQEEESLIIELHAALGNRWSQIATRLPGRTDNEIKNFWNSCLKKKLRRKGIDPTTHKPLINDLHQCLETHDIIDQKLTSSQILKSTASINQLQDTTTTWCFPTMMTTNQNAAFCNTTTNPTVSDQIVSLISSMSTSASPTPNYNLVPNNWELNYNNSVPCQSIYSTFFGNHYTDQTTQIMNNNNTNNNQEMKSWGLEILDQYTDQSCLEIEVKPEINKFYWKSSSSSPPNQLDVTEPILKFVGPQVQNVFKF