Information report for 478481
Gene Details
Functional Annotation
- Refseq: XP_020888243.1 — transcription factor MYB65 isoform X1
- Swissprot: Q9FR97 — MYB65_ARATH; Transcription factor MYB65
- TrEMBL: D7LAN1 — D7LAN1_ARALL; Transcription factor
- STRING: fgenesh2_kg.3__1182__AT3G11440.1 — (Arabidopsis lyrata)
- GO:0009723 — Biological Process — response to ethylene
- GO:0009751 — Biological Process — response to salicylic acid
- GO:0009908 — Biological Process — flower development
- GO:0043068 — Biological Process — positive regulation of programmed cell death
- GO:0045893 — Biological Process — positive regulation of transcription, DNA-templated
- GO:0045926 — Biological Process — negative regulation of growth
- GO:0048235 — Biological Process — pollen sperm cell differentiation
- GO:0005634 — Cellular Component — nucleus
- GO:0003677 — Molecular Function — DNA binding
Family Introduction
- MYB factors represent a family of proteins that include the conserved MYB DNA-binding domain.The first MYB gene identified was the ‘oncogene’ v-Myb derived from the avian myeloblastosis virus . Evidence obtained from sequence comparisons indicates that v-Myb may have originated from a vertebrate gene, which mutated once it became part of the virus. Many vertebrates contain three genes related to v-Myb c-Myb, A-Myb and B-Myb and other similar genes have been identified in insects, plants, fungi and slime moulds. The encoded proteins are crucial to the control of proliferation and differentiation in a number of cell types, and share the conserved MYB DNA-binding domain. This domain generally comprises up to three imperfect repeats, each forming a helix-turn-helix structure of about 53 amino acids. Three regularly spaced tryptophan residues, which form a tryptophan cluster in the three-dimensional helix-turn-helix structure, are characteristic of a MYB repeat. The three repeats in c-Myb are referred to as R1, R2 and R3; and repeats from other MYB proteins are categorised according to their similarity to either R1, R2 or R3.
- In contrast to animals, plants contain a MYB-protein subfamily that is characterised by the R2R3-type MYB domain. MYB proteins can be classified into three subfamilies depending on the number of adjacent repeats in the MYB domain (one, two or three). We refer to MYB-like proteins with one repeat as ‘MYB1R factors’, with two as ‘R2R3-type MYB’ factors, and with three repeats as ‘MYB3R’ factors.
Literature and News
Gene Resources
Homologs
- Arabidopsis thaliana: AT3G11440.1, AT3G11440
- Brassica napus: GSBRNA2T00020136001, GSBRNA2T00000303001, GSBRNA2T00051216001
- Brassica oleracea: XP_013585871.1, XP_013585870.1, XP_013585872.1, XP_013616289.1, XP_013616281.1, XP_013616297.1
- Brassica rapa: XP_009146724.1, XP_009146725.1, XP_009121136.1, XP_009121138.1
- Raphanus raphanistrum: RrC17852_p1
Sequences
CDS Sequence:
- >478481|Arabidopsis_lyrata|MYB|478481
ATGAGTTACACAACAACCACGGTTGATAGTGATGATGGTATGCACTCCAGCATCCATAATGAATCACCAGCTGCTGATAGTATTAGCAATGGCTGCAGAAGTAGAGGGAAAAGCCGTGTCCTGAAGAAAGGACCATGGACTTCAACTGAAGACGGGATTTTAATTGATTATGTAAAGAAGCATGGCGAGGGTAACTGGAATGCTGTGCAGAAACACACGAGCCTGGCCCGTTGTGGTAAAAGCTGTCGTCTGAGATGGGCTAATCATCTGAGGCCAAACTTGAAGAAAGGAGCATTTAGCCAAGAAGAAGAACAGCTCATTGTTGAAATGCACGCCAAGATGGGAAATAAATGGGCACAGATGGCTGAACATTTACCTGGTCGAACAGATAATGAGATAAAGAATTATTGGAACACTCGTATCAAGAGGAGACAACGTGCAGGCTTACCACTTTACCCTCCTGAAATCCATGTTGAAGACTTTCAGTGGAGCGAAGAGTATACAAAGAGTAATATCATAAGAGTAGATAGAAGAAGACATCAAGATTTCTTGCAGTTGGGGAATTCCAAAGCTAATGTCTTATTTGATGATCTAAATTTTGCTGCTAGCTTGTTACCTGCCGCTTCTGACCTATCAGATTTGGTTGCATGCAACATGCTAGGAACTGGCCCAAGTTCTTCCCGGTATGAAAGCTACATGCCACCAATATTGCCTTCCCCAAGGCAAATCTGGGAATCTGGATCTCGGTTTCCTATGTGCAGCAGTAACATAAAGCATGAATTCCAATCTCCGGAACACTTTCAGAATACTGCTTCACAGAAGAATCCCAGATCTTGCAGTATCTCGCCTTGTGATGTTGATCATCCTCCTTACGGAAACCAACATTTATCTGATATGATGATTCCAGATAGCCATACCCTTATGTATGGCATGCTTCCTACTTCTAAGCCCTCGTTTGGGGCAGTGAAGCTGGAGCTCCCTTCATTCCAATATTCAGAAACTAGTGCATTTGATCAGTGGAAGACGACACCGTCACCTCCACACTCAGATCTCCTTGACTCTGTTGATGCCTATATTCAATCTCCACCATCATCGCAGGTAGAGGAGTCAGATTGTTTCTCTTCATGCGACACCGGCCTACTAGATATGTTACTTCATGAGGCCAAGATCAAAACTAGTGCGAAGCACAGTTTGTTGATGTCATCACCCCAGAAGAGTTTCAGTTCAACTACTTGCACGACCAATGTTACTCAGAATGTACCACGTGGCGGCACACTGATCAAATCAGGTGAATATGAAGATTCCCAAAAGAATTTGACTCGCTCTGAGATTACAATGCCCATGCAACTTAGCGCAGGTGGAATTTCATCAGCTTTTGCAGGGAATGTTGTAAAGACAGAAGAGTTTGATCAGGTTTGGGAACCAAAGAGAGTTGATACTACACGGCCTGATGTTTTACTTGCGTCGAGCTGGCTTGACCAAGGCTGTTTTGGGATTGTTAGAGATACAAGCAGCATGAGCGATGCGCTTGCGCTTCTTCTTGGTGGTGACGACACTGGGAACAGTTACGTGACTGTTGGGTCATCATCAGGTCAAACACCACGAGGCGTCGGGTCTTGTGGATGGACTAATATGCCTCCCGTTTGGTCGTTGTAA
Protein Sequence:
- >478481|Arabidopsis_lyrata|MYB|478481
MSYTTTTVDSDDGMHSSIHNESPAADSISNGCRSRGKSRVLKKGPWTSTEDGILIDYVKKHGEGNWNAVQKHTSLARCGKSCRLRWANHLRPNLKKGAFSQEEEQLIVEMHAKMGNKWAQMAEHLPGRTDNEIKNYWNTRIKRRQRAGLPLYPPEIHVEDFQWSEEYTKSNIIRVDRRRHQDFLQLGNSKANVLFDDLNFAASLLPAASDLSDLVACNMLGTGPSSSRYESYMPPILPSPRQIWESGSRFPMCSSNIKHEFQSPEHFQNTASQKNPRSCSISPCDVDHPPYGNQHLSDMMIPDSHTLMYGMLPTSKPSFGAVKLELPSFQYSETSAFDQWKTTPSPPHSDLLDSVDAYIQSPPSSQVEESDCFSSCDTGLLDMLLHEAKIKTSAKHSLLMSSPQKSFSSTTCTTNVTQNVPRGGTLIKSGEYEDSQKNLTRSEITMPMQLSAGGISSAFAGNVVKTEEFDQVWEPKRVDTTRPDVLLASSWLDQGCFGIVRDTSSMSDALALLLGGDDTGNSYVTVGSSSGQTPRGVGSCGWTNMPPVWSL*