Information report for 29628.m000773
Gene Details
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Functional Annotation
- Refseq: XP_002528786.2 — dnaJ homolog subfamily C member 2
- TrEMBL: B9SS17 — B9SS17_RICCO; Zuotin, putative
- STRING: XP_002528786.1 — (Ricinus communis)
- GO:0005634 — Cellular Component — nucleus
- GO:0003677 — Molecular Function — DNA binding
Family Introduction
- MYB factors represent a family of proteins that include the conserved MYB DNA-binding domain.The first MYB gene identified was the ‘oncogene’ v-Myb derived from the avian myeloblastosis virus . Evidence obtained from sequence comparisons indicates that v-Myb may have originated from a vertebrate gene, which mutated once it became part of the virus. Many vertebrates contain three genes related to v-Myb c-Myb, A-Myb and B-Myb and other similar genes have been identified in insects, plants, fungi and slime moulds. The encoded proteins are crucial to the control of proliferation and differentiation in a number of cell types, and share the conserved MYB DNA-binding domain. This domain generally comprises up to three imperfect repeats, each forming a helix-turn-helix structure of about 53 amino acids. Three regularly spaced tryptophan residues, which form a tryptophan cluster in the three-dimensional helix-turn-helix structure, are characteristic of a MYB repeat. The three repeats in c-Myb are referred to as R1, R2 and R3; and repeats from other MYB proteins are categorised according to their similarity to either R1, R2 or R3.
- In contrast to animals, plants contain a MYB-protein subfamily that is characterised by the R2R3-type MYB domain. MYB proteins can be classified into three subfamilies depending on the number of adjacent repeats in the MYB domain (one, two or three). We refer to MYB-like proteins with one repeat as ‘MYB1R factors’, with two as ‘R2R3-type MYB’ factors, and with three repeats as ‘MYB3R’ factors.
Literature and News
Gene Resources
Sequences
CDS Sequence:
- >29628.m000773|Ricinus_communis|MYB|29628.m000773
ATGAATTTTACTTGTCAAGCAGGGTTCTGGGTAGGAGTGAAGCTGTTCTTGGAGATTGATTTTCCCCAACTTATTGTCAGCTTTTCTTGGAGATTGATTTTCCCCAACTTATTATCAGCTTTTTACACCTTTGTAAGCATTATGGCCGTCACTTCTAGGATACGGCTTATTTCCTATTCACAAGAGCTTGTAGATGGACAGCCAGTCTATCTCTCTTCAAATTCCCTCCCAATCAAGGCATTGAAATTTGAACCTGCTGGTCATGCATTTCACACTGTTGCTCAAAAACTCCTTGGCTGCGAGGAAGAGGATGTGGACAGTGAAGATCAGAAAGTGCCTAATGAAAAGGAACAGTCATACATGCCATCTTCTGATTCTTATAGCAGCAAAGGTAAAAAGAAATCTGGAGACAAGCAACAGGATCACTATGCCTTGTTAGGTTTGAGCCATTTGAGATATCTTGCAACAGAAGAACAGATACGGAAAAGTTATCGTGAGGTTGCTTTGAAATATCATCCTGATAAACAGGCAGCTATTCTTCTTGCTGAGGGAACTGAGGCTGCAAAGCAAGCCAAAAAGGATGAAATAGAGAGCCACTTCAAAGCTATCCAAGAAGCATATGAAGTTTTGATCGATCCTATAAAGAGAAGAATATATGACTCTAGCGATGAGTTTGATGATGAAATTCCAACTGACTGTGCACCTCAGGACTTCTTCAAGGTTTTCGGTCCTGCTTTTCTGAGGAATGGACGGTGGTCAGTAACCCAGCCAATCCCACCTTTAGGCGATGATAACACATCCTTGAAAGAAGTCGAGAACTTCTATGATTTCTGGTACAGTTTTAGGAGCTGGAGAGAGTTCCCACATGCTGATGAATTTGATCTTGAGCAAGCTGAATCTCGCGAACATAAGAGGTGGATGGAGAGGCAAAATGCCAAACTCACTGAGAAGGCAAGGAAGGAAGAATATGCAAGAATTCGTACTCTTGTTGACAATGCTTATAAAAGAGATCCAAGAATATTGAGGAGAAAGGAAGAGGAAAAAGCTGAAAGGCAGAGAAAGAAGGAAGCTAAAATCTTGGCAAAGAAGTTGCAGGAGGAAGAAGCTGCCAGGGCTGCTGAAGAGGAGAAACGTCGTAAAGAGGAGGAGGAAAAACGTGCTGCTGAAGCTGCTTTGCAGCAGAAGAAGGTAAAGGAGAAAGAGAAGAAGCTTCTGCGCAAAGAGCGGACTCGTCTTCGAACACTTTCAGCACCTATTTTGTCCCAGCGCATGCTTAATCTTTGTGAGGAGGATGTGGAAAATCTTTGTTTGTCATTGGATATTTTGCAGCTCAGGGATATATGCGAGAAGATGGAGGGTAAACAAGTGCTAGACCAAGCAAAAGTGCTCAGTGATGCTAGTGGGCACAAACATGACTCTGAGAGCATTAAACAAGAAGAGAAGAAGAAATTACAGCAGAATGGTTCTGTGGAATTGAACGGAAGTGTCCCATTAAGCAGCTTTGAAAAGAAAGAGAAGCCTTGGAGCAAAGAAGAAATTGAGCTCTTGAGAAAAGGAATGCAGAAATATCCCAAAGGAACATCTCGGAGGTGGGAGGTTATTTCAGAATACATTGGCACAGGAAGATCTGTTGAAGAAATTCTGAAGGCAACAAAAACTGTTCTCCTTCAAAAGCCTGACTCTGCTAAAGCTTTTGATTCTTTTCTTGAGAAGAGGAAGCCCGCACAATCTATTGCATCTCCACTTACAACTAGAGAGGAAATAGAAAGGGTAGCAAGTAAACAAGGGCCTGAAAGCAGCGCCACAAAGATTGATGGTTCAGAGGAATCTTTTAGTAGGTCTGCAAATAACAAGAATCCTGATGATGTTATTGCTGAGAATGGGGGGCCTTCAAGTTCAGATCAGGATGCATGGTCCGCTGTACAAGAAAGAGCGCTAGTTCAGGCTCTAAAAACATTCCCAAAAGAAACCAGTCAACGTTGGGAGCGAGTTGCAGCTGCTGTTCCTGGGAAGACGGTGAATCAATGCAAGAAAAAATTTACTTTGCTAAAGGAAAATTTCAGAAACAAGAAAAGTGCAGTTTAG
Protein Sequence:
- >29628.m000773|Ricinus_communis|MYB|29628.m000773
MNFTCQAGFWVGVKLFLEIDFPQLIVSFSWRLIFPNLLSAFYTFVSIMAVTSRIRLISYSQELVDGQPVYLSSNSLPIKALKFEPAGHAFHTVAQKLLGCEEEDVDSEDQKVPNEKEQSYMPSSDSYSSKGKKKSGDKQQDHYALLGLSHLRYLATEEQIRKSYREVALKYHPDKQAAILLAEGTEAAKQAKKDEIESHFKAIQEAYEVLIDPIKRRIYDSSDEFDDEIPTDCAPQDFFKVFGPAFLRNGRWSVTQPIPPLGDDNTSLKEVENFYDFWYSFRSWREFPHADEFDLEQAESREHKRWMERQNAKLTEKARKEEYARIRTLVDNAYKRDPRILRRKEEEKAERQRKKEAKILAKKLQEEEAARAAEEEKRRKEEEEKRAAEAALQQKKVKEKEKKLLRKERTRLRTLSAPILSQRMLNLCEEDVENLCLSLDILQLRDICEKMEGKQVLDQAKVLSDASGHKHDSESIKQEEKKKLQQNGSVELNGSVPLSSFEKKEKPWSKEEIELLRKGMQKYPKGTSRRWEVISEYIGTGRSVEEILKATKTVLLQKPDSAKAFDSFLEKRKPAQSIASPLTTREEIERVASKQGPESSATKIDGSEESFSRSANNKNPDDVIAENGGPSSSDQDAWSAVQERALVQALKTFPKETSQRWERVAAAVPGKTVNQCKKKFTLLKENFRNKKSAV