Information report for 109587
Gene Details
Functional Annotation
- Refseq: XP_002978781.2 — transcription factor MYB34 isoform X2
- Refseq: XP_002984694.2 — transcription factor MYB34 isoform X2
- Swissprot: Q9SZP1 — MYB4_ARATH; Transcription repressor MYB4
- TrEMBL: D8S5T8 — D8S5T8_SELML; Uncharacterized protein MYB4A-1 (Fragment)
- STRING: EFJ20228 — (Selaginella moellendorffii)
- GO:0009751 — Biological Process — response to salicylic acid
- GO:0009753 — Biological Process — response to jasmonic acid
- GO:0010224 — Biological Process — response to UV-B
- GO:0045892 — Biological Process — negative regulation of transcription, DNA-templated
- GO:0090378 — Biological Process — seed trichome elongation
- GO:1903086 — Biological Process — negative regulation of sinapate ester biosynthetic process
- GO:0003677 — Molecular Function — DNA binding
Family Introduction
- MYB factors represent a family of proteins that include the conserved MYB DNA-binding domain.The first MYB gene identified was the ‘oncogene’ v-Myb derived from the avian myeloblastosis virus . Evidence obtained from sequence comparisons indicates that v-Myb may have originated from a vertebrate gene, which mutated once it became part of the virus. Many vertebrates contain three genes related to v-Myb c-Myb, A-Myb and B-Myb and other similar genes have been identified in insects, plants, fungi and slime moulds. The encoded proteins are crucial to the control of proliferation and differentiation in a number of cell types, and share the conserved MYB DNA-binding domain. This domain generally comprises up to three imperfect repeats, each forming a helix-turn-helix structure of about 53 amino acids. Three regularly spaced tryptophan residues, which form a tryptophan cluster in the three-dimensional helix-turn-helix structure, are characteristic of a MYB repeat. The three repeats in c-Myb are referred to as R1, R2 and R3; and repeats from other MYB proteins are categorised according to their similarity to either R1, R2 or R3.
- In contrast to animals, plants contain a MYB-protein subfamily that is characterised by the R2R3-type MYB domain. MYB proteins can be classified into three subfamilies depending on the number of adjacent repeats in the MYB domain (one, two or three). We refer to MYB-like proteins with one repeat as ‘MYB1R factors’, with two as ‘R2R3-type MYB’ factors, and with three repeats as ‘MYB3R’ factors.
Literature and News
Gene Resources
Sequences
CDS Sequence:
- >109587|Selaginella_moellendorffii|MYB|109587
ATGGGCCAATTATGTGATTTTTGCAGCGAGCAAATATCCATGGTCTATTGTAGGTCCGATGCAGCGTGCTTATGTTTATCCTGTGATCGGAACATTCATTCTGCAAATGCTCTTTCTAAGCGCCACTTGAGGACCCTTGTATGTGAACAATGCCATCATCAGGCTGCAGTTGTCAGGTGCATGGAAGAGAACGTCTCCCGATGTCAAAACTGCAATTGGTCTGCACATGCTGCCCCTTCTTCAGCTATGGAGCACAAAAGGGAGACAATCAATTGTTATTCAGGATGCCCATCTGCAGCTGAGTTTTCAACGATTTGGCCCTTCTTTTCTGTTGATTTGTCAAGTTGCAATCTTGAAGCCGATTCCATGAGTAATGAAGAGGAATATGAAAGGCGCCCTCAATCTCAATCGTTGCCGATTGGTTATAGTACAGAAGATGCTGCTCTGGATACCAATGCATCTAAGCTAGAGCAATTTAATGGGAGTGAATCTTTTAATCCTCTCAATCAGAAGGCATGTTTATCGAGAATAAAGCATCTTGACTCCATTGATGATACTCTCTACCTGGACTTCGGTATCTCAGATATCGACTTGGATTTGGAAAACTATGGAGCAGTTTTTGATGAACTTGATGATCCACAACAATTTTTTGAGAATGGTGGAATTGATAGCTTGTTCGAGCATGGTACTGAATGCAATGTCAAGAGTGTAAAGGAATCCAGCTCCAAGAGTGAAACCATGCAGCAGGCATGCAGTAAACAAGTATCTGCTGACTCCATTACAAGCTGTAAGTCCGATACACACATTTGCTTTACAGAACCCGCGCAATCTACTCTCTCACTTTCGTTTCTGGCGCCGGATCATGAGTGTGAAACTAAAGATCACCTAGATTGTGAAGGGTTTTCAATGGCTACAATAGAGGAACATCCGTGCAATATTCCTTATCCTGGAAATCAGTTTTCATCAGCTATCAGGGATGGTGCAGTCTTGCGGTATAAAGAGAAAAGGAAGTCAAGGAAGTTCAATAAAAAAATAAGGTATGCTTCACGCAAGGCGAGGGCTGATGTTAGGAAGCGTGTGAAGGGACGTTTTGTGAAAACCGGTGATCCGTATGATTATGACCCGCTGGACTTGACAAGAATTCACTGA ATGGGGCGGGCTCCATGTTGCGAAAAAGTGGGACTCAACAGGGGCCCCTGGACGAGAGAGGAGGATGCTCTCCTGATCAAGTATATTACCGCACACGGCGAAGGATCCTGGCGTACATTGCCGAAACAAGCAGGACTGAGACGGTGTGGTAAAAGTTGCAGGCTGAGGTGGATCAATTACCTCCGGCCTGATCTCAAACGAGGAAACATCACCGAGGAGGAGGACGAGCTCATCATTAAGTTGCATTCGCTGCTTGGTAACAGATGGTCACTGATCGCGGGCCGGTTAGCAGGACGCACGGACAACGAAATAAAGAATTACTGGAACACTCACCTCAAAAAGAAGCTCCGTAGCATGGGGATCGATCCTCACACGCACAGGCCTCTG
Protein Sequence:
- >109587|Selaginella_moellendorffii|MYB|109587
MGRAPCCEKVGLNRGPWTREEDALLIKYITAHGEGSWRTLPKQAGLRRCGKSCRLRWINYLRPDLKRGNITEEEDELIIKLHSLLGNRWSLIAGRLAGRTDNEIKNYWNTHLKKKLRSMGIDPHTHRPL