Information report for Zm00001eb068790
Gene Details
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Functional Annotation
- TrEMBL: A0A3L6D800 — A0A3L6D800_MAIZE; Casein kinase 1-like protein HD16
- STRING: Zm00001eb068790 — (Zea mays)
- GO:0043547 — Biological Process — positive regulation of GTPase activity
- GO:0003677 — Molecular Function — DNA binding
- GO:0005089 — Molecular Function — Rho guanyl-nucleotide exchange factor activity
Family Introduction
- A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.
Literature and News
Gene Resources
- SuperFamily: SSF46689
- SMART: SM00389
- Gene3D: G3DSA:1.10.10.60
- PROSITE profile: PS50071
- Pfam: PF00046
- PROSITE pattern: PS00027
- Gene3D: G3DSA:1.20.5.170
- InterPro: IPR009057 IPR001356 IPR017970
Homologs
- Oryza sativa: OsRacGEF1;OsRopGEF7B, LOC_Os03g57940, CKI;EL1
- Saccharum spontaneum: Sspon.01G0048730-2D
- Setaria italica: SETIT_034472mg
- Setaria viridis: SEVIR_9G058300v2
Sequences
CDS Sequence:
- >Zm00001eb068790|Zea_mays|HB-other|Zm00001eb068790
ATGGCGGAGTATATGCTGGTGGTGCAGAGCAATCTTAACCAATGTAATAACGAAGATATCCCGCTTTCTGGAACAAAAATTGAGATGGAGTCTTACGAACAAGAATCATCTGACAGCAGTGATGAAGAGTGGTCCACACTTAGCACACCACGAAAAACAAAATTACAAGGCAACGAAAAAGTATCACTTACTGAATCAGTACGTTCTGCAAAGCGGTGTTCTAGAAGAGCGCCAGCTAGGGAGCATAATAATGAACATACTCAGAGTGAGCAGCTTCATGGTTCTGCAAGTGAGCAGCAAGCTAGAGAGCAACTTCATGGTTCTGTAAGTAAACAGCAAACTGAAGTTCTTCGCTCCAATGTCAGCAGTGGCGATGCCTCAAAATGCCATTTTGGCCCTATAGTTACTCAGAAGCTGAAGGAACATTTTGAAAAAGATCCATATCCTTGCCATGCAACAAAAGAGGGTCTGGCACAAGAGCTAGGACTGACATTTAATCAGGAAATCCTGGAAAGCTTGAGAGACCCGGAATTCTGGTATGTTGAGCAAGGTATCGCTGCACCAGACTGCGACGGCTCTGCCTCCTTCAGGGTGGCTTTCCACCGCCGTGATGAGAAGTGGTGGCTCTCGGTGCCTCGTGTGCCTCCCGGTGGCCTTCACAACAAAACAAGGAAGCAGCTCCAACACAAGCGTGATTGTGCAAACCAAATCCTGAAGGCTGCCATGGCCATCAACAGCAATACTTTAGCAGAGATGGAGGTCCCTGAACCTTATCTTGACTCCCTACCAAAGAATGGACGGTCAACCTTAGGTGATATCATATACCGCTACATAACCTCTGATCAGTTCTCCCCTGAGTGCCTTCTTGATTGCCTGGATCTGTCCACGGAGTACCAGGCCCTGGAAGTCGCAAACCGTGTTGAGGCGTCAGTGTATGTGTGGCGCCGGAGGGTTGCTGCCAAACCAGTAAATGGATTGGGCCGAAGCAACAGTGCTAGATCATCGTGGGGCATGAGCTATTCGAGGGTGTTAGACAGTTTGGCTTCAAACATCGTCACCCGCATCGACGATCTGCTGAACATTGACGAGCTGAACGAACACGCTGAACATTTCGCAGCAATAGGTGACGTTGACTGCAAGATTGCAGTCAGCCAGACTGCTGCTGTTCCATCCTTCCCAGTGCCAGCCTCTAGCACGCCATTCATGACGGCATATACCACGCCGAGCTTCTCGCCGGCGCAATTGGCAAGCCCATTGAAGAAAGAGAAGACGTCGCTGACTCCAGGCAGACGTTCTCAGCACAGTAGGGGTGCTGGCACAAAGAAAGGCTTGATGGATCGTGTGGGTACAAAAATCAAGGGGATGATGATCAGCAACGGTATGATGATCAATGTCTCTACAACTACGGAGCTCTCTCAGAAGTTAGAATTAGTACCTAACAATGGTCTTTGGCGCCAAACATGGCCACTTTTTATTGCAACCCCTCTTGATAAACGTTTATCTAACATTCCAATCAGATGTCTGGGCTATGTTTTCAAGCAAAGTTGTAGCCTGGGACTCAAATTTCATTGGCTTCAAGAGAAAATTACTGATCACAAATTTCATTGGCTTCAAGATAATAAGAATAAGGGCGCCGCCAGCCTCCACAGGATACTTTGTTGTTATTGTCCAGCTCCATTCAAACAGTTTCTTGAGATTGTCACAAATATGAAATTTGACGAAGAGCCAAATTATGCCAAGCTTATCTCTCTTTTTGATGGTTTGATTGAAGCACCTGCTTCGAGACAAATCAGAATTGATGGGGCTCTCAAGGTTGGACAGAAATGTGGAAGATTGGTTGCAGATCTAGAAGAAGTTGAACAACCTAAAAAGAAGGTTAGATTAGGGAGCCCAGCGGCTCAATGGATTTCAGTTTATAATGCTAGGTGGCCCATGAAGCAGAGGTACCATTACAATGTGGCTGACTCAAGGCTAAGCCAACATATAGAAAAGGGCAACGATGATGGGCTTTACAAACCTTTGGGCACTCATCATGGACGCAGGAACTGGTTTCTGTTCTCAGGAACTCCTTACACCCAGCAATCATACAAGGTTAGTGAGTCGTTTCCTTACAAGTGGATCAATAAGAAGTGGAAAGAAGGGTTCCATGTGACATCCATGGCCACCGCTGGGAATCGCTGGGGCGTAGTCATGTCAAGGAATTCAGGGTTCTCTACTCAGGTTGTAGAGTTGGATTTCCTGTACCCCAACGAAGGCATCCACCGACGCTGGGAGAGCGGCTACAGGATAACTTCCACGGCGGCCACCAACAACCAAGCCGCTTTCATCCTGAGCATGCCAAAGCGGAAGCCGATGGACGAGACCCAGGAAACGCTCCGGACCTCCGCCTTCCCCAGCTCACACGTCAAGATCTCGCTGCCATTTGCATCTCCTGTCACCGTTCTAAGCTGA
Protein Sequence:
- >Zm00001eb068790|Zea_mays|HB-other|Zm00001eb068790
MAEYMLVVQSNLNQCNNEDIPLSGTKIEMESYEQESSDSSDEEWSTLSTPRKTKLQGNEKVSLTESVRSAKRCSRRAPAREHNNEHTQSEQLHGSASEQQAREQLHGSVSKQQTEVLRSNVSSGDASKCHFGPIVTQKLKEHFEKDPYPCHATKEGLAQELGLTFNQEILESLRDPEFWYVEQGIAAPDCDGSASFRVAFHRRDEKWWLSVPRVPPGGLHNKTRKQLQHKRDCANQILKAAMAINSNTLAEMEVPEPYLDSLPKNGRSTLGDIIYRYITSDQFSPECLLDCLDLSTEYQALEVANRVEASVYVWRRRVAAKPVNGLGRSNSARSSWGMSYSRVLDSLASNIVTRIDDLLNIDELNEHAEHFAAIGDVDCKIAVSQTAAVPSFPVPASSTPFMTAYTTPSFSPAQLASPLKKEKTSLTPGRRSQHSRGAGTKKGLMDRVGTKIKGMMISNGMMINVSTTTELSQKLELVPNNGLWRQTWPLFIATPLDKRLSNIPIRCLGYVFKQSCSLGLKFHWLQEKITDHKFHWLQDNKNKGAASLHRILCCYCPAPFKQFLEIVTNMKFDEEPNYAKLISLFDGLIEAPASRQIRIDGALKVGQKCGRLVADLEEVEQPKKKVRLGSPAAQWISVYNARWPMKQRYHYNVADSRLSQHIEKGNDDGLYKPLGTHHGRRNWFLFSGTPYTQQSYKVSESFPYKWINKKWKEGFHVTSMATAGNRWGVVMSRNSGFSTQVVELDFLYPNEGIHRRWESGYRITSTAATNNQAAFILSMPKRKPMDETQETLRTSAFPSSHVKISLPFASPVTVLS