Gene Details:
- Gene ID: AT5G44180.2
- Gene Name: RLT2
- Gene Family: HB-other Family
- Description: HB-other Family protein
- Species: Arabidopsis thaliana
- Source: HB-other family gene from PlantTFDB
Protein Features:
- SuperFamily: SSF46689
- SMART: SM00389
- Gene3D: G3DSA:1.10.10.60
- PROSITE profile: PS50071
- Pfam: PF00046
- PROSITE pattern: PS00027
- Gene3D: G3DSA:1.20.5.170
- InterPro: IPR009057 IPR001356 IPR017970
Annotation Proteins:
- Refseq: NP_001190470.1 — Homeodomain-like transcriptional regulator
- Swissprot: Q9FFH1 — RLT2_ARATH; Homeobox-DDT domain protein RLT2
- TrEMBL: F4K8S9 — F4K8S9_ARATH; Homeodomain-like transcriptional regulator
- STRING: AT5G44180.1 — (Arabidopsis thaliana)
Gene Ontology:
- GO:0006355 — Biological Process — regulation of transcription, DNA-templated
- GO:0009908 — Biological Process — flower development
- GO:0010228 — Biological Process — vegetative to reproductive phase transition of meristem
- GO:0005634 — Cellular Component — nucleus
- GO:0003677 — Molecular Function — DNA binding
- GO:0003700 — Molecular Function — transcription factor activity, sequence-specific DNA binding
- GO:0005515 — Molecular Function — protein binding
Family Introduction:
- A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.
Literature:
Sequences:
CDS Sequence:
- >AT5G44180.2|Arabidopsis_thaliana|HB-other|AT5G44180.2
ATGGAAGGTGGGTCTGAAAAAACAACACCTGAAGGTTGTGGTGGTGAGAGTAAGTCTAAACGGAAAATGAAAACTGCTGCTCAACTTGAAGTTCTTGAAAACACTTATTCAGCTGAGCCTTATCCTTCGGAAGCTATAAGAGCGGATCTCTCAGTGAAACTGAATCTTTCCGATAGACAGTTACAGATGTGGTTTTGTCACCGGCGGCTTAAAGAACGGAAATCTACTACGCCGAGCAAACGTCAGCGTAAGGAGTTAGTAACTCCAACGGCTATGGAATCCTGGGAACCACCCGTCAATGCCGGTGATTTAGTGGCGGGAAATGAGCTTGATTCTAGAAGAGCTGCTCGAGGCAGTGGCGGTAGTGGTGTGACGGTTGTGAGGCGGTTTAATGAACCGTCTTCTGCTGAGGTTAGAGCTATTGGTTATGTTGAAGCTCAATTGGGAGAGCGGTTGAGAGATAACGGACCGGTTCTTGGAATGGAGTTTGATCCTTTACCTCCTGGTGCATTTGGCATGCCTATTGAGATGCCAAGCCATCGCAAGGCGACTAGGCAAGCTTTCGAGACCAACATATATGTCCGATCCGATGTCAAGCCTATCAAAGATCATGTGAGGCCTATTCGTGAATATCAGTTCATTCCTGAGCTGCCATCTTCGAGGACTGATCATTCGGAACGAGTTTCTCCGTCACATCATTTTGGAGTTCCACTTGATGGTTCGGTTATGAGGGTTTCAGCTGTGTCTGCTGGACATCGGGATGACTATAAAATTTCACCTCAGATACCAAATTTGAATCTTGCAACTCATCAAGGGAAGCCGGGGCATGTCTATTCGCCTAACTTGGTCGAATATGACTCACCGTATCAGAAAAGCTACATGGATACTGCTGCACAAGTTCATGATGATCCTTTTGTGAAATCAGAGAGAGAAGTTGGTAATGAGGATGAGGATGATGATGCCCTGCAATTAGAGAGACACCGCAAGAATGAAGAAGCAAGAATAGCTCGGGAAGTCGAGGCTCATGAGAAGAGGATCCGAAGGGAACTAGAGAAACAAGATATGCTGAGGCGAAAGAGAGAAGAGCAAATAAGGAAAGAAATGGAGAGGCAAGATCGTGAAAGACGGAAAGAGGAAGAACGTCTTTTACGTGAAAAACAGAGAGAGGAAGAGAGGTACCTTAAAGAGCAGATGCGAGAGTTGCAGCGAAGAGAGAAGTTCTTGAAGAAAGAAACAATCAGGGCTGAGAAAATGCGACAAAAAGAAGAGATGCGTAAAGAAAAAGAGGTTGCCAGGCTTAAAGCTGCTAATGAGAGGGCCATTGCTCGTAAGATCGCAAAGGAATCTATGGAACTTATTGAAGATGAACGCTTAGAGCTCATGGAGGTTGCTGCGTTAACAAAAGGCTTGCCTTCAATGCTCGCCCTTGACTTTGAAACTCTACAGAACCTCGATGAATATAGAGACAAGCAGGCAATATTTCCCCCAACATCTGTAAAATTGAAAAAGCCCTTTGCAGTCAAGCCGTGGAATGGTTCTGATGAGAATGTTGCAAATCTTCTTATGGTGTGGAGATTCTTAATCACTTTCGCAGACGTTCTTGGTCTTTGGCCATTTACCCTGGACGAGTTTGCTCAGGCATTCCATGACTATGACCCACGGCTAATGGGAGAGATACACATTGTTCTATTGAAGACTATAATCAAAGATATCGAGGGTGTGGTAAGAACGCTGTCGACCGGTGTTGGAGCAAACCAGAATGTTGCTGCTAATCCCGGAGGGGGTCATCCTCACGTTGTGGAGGGTGCATACGCGTGGGGTTTTGATATACGCAGCTGGAGAAAAAACTTGAATGTTTTTACATGGCCTGAAATCTTGAGGCAACTCGCTCTCTCTGCCGGGTTGGGACCGCAACTGAAGAAAATGAACATTAGGACTGTGTCTGTTCATGATGACAATGAGGCCAACAACTCTGAGAATGTGATTTTCAACCTAAGGAAAGGAGTAGCAGCTGAGAATGCTTTTGCCAAGATGCAAGAGAGGGGACTTTCTAATCCACGACGTTCACGGCATCGTTTGACTCCAGGCACTGTTAAGTTTGCTGCATTTCATGTTCTATCTCTTGAAGGTGAAAAAGGTTTGAACATTCTTGAGGTTGCAGAGAAGATTCAGAAATCAGGATTGAGGGATCTAACGACGAGTAGGACACCTGAAGCCTCGGTTGCTGCTGCGTTGTCTCGAGATACAAAACTCTTTGAGAGGGTAGCTCCTTCTACGTATTGTGTACGTGCTTCCTATAGAAAAGATGCAGGTGATGCTGAGACTATATTTGCTGAAGCGAGAGAGAGAATACGTGCATTCAAGAGCGGCATCACTGATGTAGAAGATGTTGATGACGCTGAGAGAGATGAAGACTCTGAAAGCGATGTCGGAGAAGACCCAGAGGTTGATGTGAACCTTAAAAAGGAAGATCCCAATCCTCTGAAGGTAGAAAACTTAATTGGAGTCGAACCATTGTTGGAAAATGGGAAACTGGATACCGTGCCCATGAAAACTGAACTGGGACTGCCTCTTACTCCCTCTCTCCCCGAGGAAATGAAAGATGAGAAAAGAGATGACACTTTAGCGGACCAATCTCTAGAGGATGCGGTAGCAAACGGTGAAGATAGTGCTTGTTTTGACGAGAGCAAACTTGGGGAACAGTGGGTTCAAGGACTTGTAGAAGGAGATTACTCGAATCTTAGCAGCGAGGAACGTTTAAACGCACTTGTTGCTCTGATTGGTATTGCCACCGAAGGAAACACAATCCGAATCGCCCTTGAGGAACGGTTGGAGGTAGCAAGTGCATTAAAGAAACAGATGTGGGGTGAAGTGCAACTCGACAAACGCTGGAAAGAAGAGTCTTTGATTCGAGCAAATTACCTCTCATACCCAACAGCAAAGCCGGGGCTTAATATCGCAACCCCTGCATCTGGAAATCAAGAAAGTTCATCAGCGGATGTGACTCCAATCTCCTCACAGGACCCGGTGAGTCTTCCACAGATCGATGTGAATAACGTGATTGCTGGACCAAGCTTGCAATTGCAAGAAAATGTACCTGGAGTGGAGAATTTGCAGTATCAGCAGCAACAGGGGTACACAGCGGACCGGGAAAGGCTGCGTGCACAGTTAAAAGCGTATGTTGGGTATAAAGCTGAAGAGCTATATGTATATAGGTCGCTTCCGCTAGGTCAAGATCGAAGACGCAATCGCTATTGGCGGTTTTCAGCATCCGCCTCTCGAAATGATCCTGGTTGTGGTAGAATATTCGTGGAACTTCAGGACGGACGCTGGAGGCTCATTGATTCCGAAGAGGCTTCTCTTCCACCTGAAGGACTTGAAGCTTTTTGGACAGAGAATCTTAGGAAATCTTGGGGTATGAAGCTGTTGTCATCAAGTTCCCATGAAGATCTTTATCAGGTTCTCACAACGTTAGAGGCAGCACTAAAGAGGGATTTCTTGTCTTCAAACTTTGAAACAACTTCTGAACTCTTGGGTTTACAAGAAGGAGCTCTCGCCAGCGATCTTACTTGTGGGGTTAATGTACTACCGTGGATACCAAAGACAGCAGGAGGTGTAGCTTTGAGACTCTTTGATTTCGACAGCTCGATTGTTTACACACCCGATCAAAACAACGATCCTCTAAAAGACAAAGAATCTGAAGATTTCGTGGGTTTGGAGACAAATATTCTGAGAAACTTACATGAGAAGGACGTAATGGAAACTCCGGTGCAAGTTGCTGCTTATAAGCAAGAAGAGAACTGGACGGATCCTGGTTTAGGTGGTGTGTCTAGCTCTGGGAGAGGAGGTCGACCACCACGAGGACGTGGCCGGCCTCGTGCCCGTGGCAATGGCAAGAAACCGGCAGTTTCTGTTAAACCACCACGAGGTGCAGCAAACTCAAATGGTGAAACCATGTTGAGACCGAGAGCACAACCACGTGGGGGTAGAAAGAATGGGCGGCGTAGTGGCACCAAAGGCCGAAAGAGACCAACGCAAGGAACACTCGGTATATGTAATGAAGTAGGAGGAGGACGTCGGGTTAAGGAAGTTGCTGTAACCGCCAAAACCAGTCTTCCTGATAACGATGACGATTGGATCGAAACCCCTGAACTGCAAGACGATGACGGAGAAGCTAGCAGCTCGGGGAGATCGTTTCAGTATGAGGACTATGATGATGATGATGTCATGGCTCCGATTGATGATTTTGATGGCGGCGGCGAATCAAGTAAATTAGTAGGTAGGGGGGAATTTAGCTTACATAGTGATGATGAATACGAAGAAGAAGAGGAAGAAGAAGAAGACATGAACATGAAAATGGATGTGAATGTTGTTGATGATGAGGATGAAGATTACATAAACGAAGACTCGTATGGTAGAAAGCAGCATGGGATTAGCATTAGCAACGATGCAGCGACTCGGAAAAGGTTTAATAAGTTTGAAGATCCTGATCTAACATCTTCATCGTCTTCTGATTTTCAATGA
Protein Sequence:
- >AT5G44180.2|Arabidopsis_thaliana|HB-other|AT5G44180.2
MEGGSEKTTPEGCGGESKSKRKMKTAAQLEVLENTYSAEPYPSEAIRADLSVKLNLSDRQLQMWFCHRRLKERKSTTPSKRQRKELVTPTAMESWEPPVNAGDLVAGNELDSRRAARGSGGSGVTVVRRFNEPSSAEVRAIGYVEAQLGERLRDNGPVLGMEFDPLPPGAFGMPIEMPSHRKATRQAFETNIYVRSDVKPIKDHVRPIREYQFIPELPSSRTDHSERVSPSHHFGVPLDGSVMRVSAVSAGHRDDYKISPQIPNLNLATHQGKPGHVYSPNLVEYDSPYQKSYMDTAAQVHDDPFVKSEREVGNEDEDDDALQLERHRKNEEARIAREVEAHEKRIRRELEKQDMLRRKREEQIRKEMERQDRERRKEEERLLREKQREEERYLKEQMRELQRREKFLKKETIRAEKMRQKEEMRKEKEVARLKAANERAIARKIAKESMELIEDERLELMEVAALTKGLPSMLALDFETLQNLDEYRDKQAIFPPTSVKLKKPFAVKPWNGSDENVANLLMVWRFLITFADVLGLWPFTLDEFAQAFHDYDPRLMGEIHIVLLKTIIKDIEGVVRTLSTGVGANQNVAANPGGGHPHVVEGAYAWGFDIRSWRKNLNVFTWPEILRQLALSAGLGPQLKKMNIRTVSVHDDNEANNSENVIFNLRKGVAAENAFAKMQERGLSNPRRSRHRLTPGTVKFAAFHVLSLEGEKGLNILEVAEKIQKSGLRDLTTSRTPEASVAAALSRDTKLFERVAPSTYCVRASYRKDAGDAETIFAEARERIRAFKSGITDVEDVDDAERDEDSESDVGEDPEVDVNLKKEDPNPLKVENLIGVEPLLENGKLDTVPMKTELGLPLTPSLPEEMKDEKRDDTLADQSLEDAVANGEDSACFDESKLGEQWVQGLVEGDYSNLSSEERLNALVALIGIATEGNTIRIALEERLEVASALKKQMWGEVQLDKRWKEESLIRANYLSYPTAKPGLNIATPASGNQESSSADVTPISSQDPVSLPQIDVNNVIAGPSLQLQENVPGVENLQYQQQQGYTADRERLRAQLKAYVGYKAEELYVYRSLPLGQDRRRNRYWRFSASASRNDPGCGRIFVELQDGRWRLIDSEEASLPPEGLEAFWTENLRKSWGMKLLSSSSHEDLYQVLTTLEAALKRDFLSSNFETTSELLGLQEGALASDLTCGVNVLPWIPKTAGGVALRLFDFDSSIVYTPDQNNDPLKDKESEDFVGLETNILRNLHEKDVMETPVQVAAYKQEENWTDPGLGGVSSSGRGGRPPRGRGRPRARGNGKKPAVSVKPPRGAANSNGETMLRPRAQPRGGRKNGRRSGTKGRKRPTQGTLGICNEVGGGRRVKEVAVTAKTSLPDNDDDWIETPELQDDDGEASSSGRSFQYEDYDDDDVMAPIDDFDGGGESSKLVGRGEFSLHSDDEYEEEEEEEEDMNMKMDVNVVDDEDEDYINEDSYGRKQHGISISNDAATRKRFNKFEDPDLTSSSSSDFQ