Information report for 55817
Gene Details
Functional Annotation
- Refseq: XP_003056615.1 — e2f1-like protein
- TrEMBL: C1MLR6 — C1MLR6_MICPC; E2f1-like protein
- STRING: XP_003056615.1 — (Micromonas pusilla)
- GO:0008284 — Biological Process — positive regulation of cell proliferation
- GO:0009733 — Biological Process — response to auxin
- GO:0010090 — Biological Process — trichome morphogenesis
- GO:0045893 — Biological Process — positive regulation of transcription, DNA-templated
- GO:0051302 — Biological Process — regulation of cell division
- GO:0051446 — Biological Process — positive regulation of meiotic cell cycle
- GO:0005634 — Cellular Component — nucleus
- GO:0005667 — Cellular Component — transcription factor complex
- GO:0005737 — Cellular Component — cytoplasm
- GO:0003677 — Molecular Function — DNA binding
- GO:0003700 — Molecular Function — transcription factor activity, sequence-specific DNA binding
Family Introduction
- E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.
- Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.
Literature and News
Gene Resources
- Gene3D: G3DSA:1.10.10.10
- SuperFamily: SSF144074
- Pfam: PF16421
- InterPro: IPR011991 IPR032198
Sequences
CDS Sequence:
- >55817|Micromonas_pusilla_CCMP1545|E2F/DP|55817
ATGATACGTGTACGTGTAGCTAGCCCTACAGCACACGGTTGTACATGTACAATAGAATACACTACGGAAGTACTGAGAAATAGATATCCGATACGGAAGTACGAAAGTACAACGTTGTACTGTAGGCCCTACGTGTACGGAAATAGATACGAAGGTACGAAGGTACCTTCGAAGGTACGAAAGTACCTTCGTACACACTATGATACCTTCGTACGGAAATACGAAGGTAATAAATACGAAAGTACGAAAGTATTTACTGTATCTTCGAAGGCACTTTCGTACGAATGTACACAACTTGTACACGTACGTGTACACGTACACATCGGTACAACATTTTTACGATGCAAGTTTTCCATATTTCGTTCAGAAGCGTTGTATAAAATCATGCAAACGCCCACAGGATCTACGTGCCGATACGACAGCTCTTTAAGTTTACTCACAAAAAAGTTCGTCTTTCTCCTCGAAAAAGCCGAGGAAGGCACAATAAATCTGAATCGAGCCGCGGAGTCTCTCGGTGTCCAGAAAAGGCGAATATACGATATTACGAACGTGTTGGAGGGCATCGGTCTTATAGAAAAGAAATCAAAAAATAATATTCAATGGAAAGTTTTACCTCCACAGTCATTCGGACTGAAATCTGGCCTATCAACAGTGACGGAAGAGATAAGAAGCATGCAAAATGACGAAATCAACCTCGACGAGCATATACAGAACATGCGAAGGAGTATGCATGTTTTGCTTGAAGATCCCGCTCACAAGGGAAACCTCTTCGTCTCAGAGGAAGACATAAAAGACTTCTTTTCTTTTCGCTCAGAAACCCTAGTCGCCGTTCGTGCACCCCATGGAACTACACTTGAAGTTCCAGATCCAGATGACAGGATGGAAATTCCTAACAAGAGATATCGAATCTTCTTGAAATCTAAAGGAGGACCAGTCGAAGTTTTTCTTGTCTCACTGCACGATAACGTGAGTGGACAGAGCTCAAAAGAGGTTCATTTCAAAAAATCACCTGTCGACCATTCGTTACAAGGTGCCGGCAGAGCGACTCCTTCTCCGTCTCGTGTTCATAGCTCCTCAGCAGCAACTCTTGCACGGGCTAGTGGACATGCTCCTTGGACGTCTTATGAAGAACGTGAAATTCCAGCGATCCTTCGCATCGCACCGCCGATTTCTGACCCTGACTTTTGGTTCTCTGATGACATAAAGGAAGTCGGCATTGGCCTAAATGATATGTACACTTCAGCAGGTCTGTCAGTGCTTCTTCAACGAAGTGCTAGGTGCCGAATGAATGCTCAACGCGAATGGCTTTCATCAAATTATGGCTCTCAAGGGACATCCACTGATAATTGA ATGCCGGTCGATTTGGATAACTCATCCACAGTTTCCGGCGACGCAAGCGTCTCATCCACCGGAAATCAAAACCCACCTCCCAAATCCGCCGGAAAAAAGAAGCGTAACCTCCCCGGCATGCCTGATCCAGACGCGGAAGTCATAGCTCTGTCGCCGAAAACCCTACTGGCGACGAACCGATTCGTCTGCGAAATCTGCAACAAGGGTTTCCAGCGTGACCAGAATCTCCAGCTCCACCGCCGCGGCCACAATCTGCCATGGAAGCTCCGGCAGAGATCGAGCAAGGAGGTGAAGAAGAAAGTCTATGTTTGTCCGGAGCCCACTTGTGTCCACCACGACCCGTCTCGCGCGTTGGGCGATCTCACCGGCATCAAGAAACACTTCTGTCGGAAACACGGCGAGAAGAAGTGGAAGTGCGAGAAATGTTCGAAGAAATACGCCGTTCAGTCCGACTGGAAGGCGCACTCGAAGATTTGCGGCACCAAGGAGTACAAATGCGACTGCGGCACTCTGTTTTCCAGGAGAGATAGCTTCATAACGCACAGAGCGTTCTGTGACGCCTTGGCTGAAGAGAGCGCGAGAAACCATAACCATGGCAAGAAGCAGAATCCTGAAATGGCTAGCCGGAAAAATCTGGAGCCCGATCCGAAATCTCCAATCGCCGCTCATTCTCCGCCGCCGCCTCTTCCTCCGGCCCCACCTCCAGCTTCCGTGGCGGCGGCAGCTGCGGGTCAGGTGGATGCCAAGCCTGCTAAGGTCATGCCCTTGTCCATTCAGCGTTCAGCCGCAGAATCACCAGAAAACCCTCCTGAAGCAATCCAGGAAGCTCCAAGGACGATCGGTTTAAATGCCATCGCCAGCAATAACACCGCCTCAGATCCAGACACCAACGATGGTAACAGTGATGGTGTGTTCGCAGGCCTGTTCTTGTCTTCCACAGCTACTCCCAGTCTATATGCTTCTTCGACAGCTTCACCCAGTCTCTTCGCACCATCCAGACCAATCGAGCCCATCTCTCTACGCCTCTCGACGAATCACGGGTCATCCTTGTTTGGGTCTACGCTGCAGGACCCAGCTCAGTTCCCGAACCCTCCTCCTCCGGCTCAGCCAGCCATGTCCGCCACCGCTCTGCTTCAGAAAGCAGCCCAGATGGGGGCTTCAGGGGGTTCATTGCTTCGTGGGTTAGGCATAGTTCCATCTTCTTCGTCGACTATGGAACTAAGCAGCAGCCACGACACGTCTCTGGCTCCTGGACTCGGACTGGGACTGCCTTGCGGAGGTGGCAACGGCTCCGGTTTGAAAGAGCTTATGATGGGAAACTCCTCAGTGTTTGGTCCGAAGCAGACAACACTCGACTTTCTGGGGTTAGGAAGGGCGGTTGGGGGAAGTGGGAGTCCAGGTGGCGGACTGTCTGCTCTGATAACCTCCATTGGAGGCGGTGGCGGCTTAGACGTCACAGCTTCGTTTGGGGCGGGAGAGTTTTCCGGCAAGGACATGGGTAGGAGCTCGTAG ATGACTACTGGGTCTAATTCTAGCCACAACCAGATAGAGGATGGTGGGGCGAAGAACAACGACAACAACACCAACCCTGGTACGAGGTCTTGGGGCACGGCGGGGTCCGGGCAAACGGTGTCCACGAGCGGCAGTGTCGGCTCGCCGTCGAGCCGGAGCGAGCATGCCACCATGGCCACACCGGCGAGCGACAGCACCTTTCTCCGGATGAACCAATTGGACATTCAGGGCGACGATGCCGGTTCCCAGGGAGCCGTAGGTGGTAAGAAGAAAAAGAGGGGCCAACGAGCAGTTGGGCCTGATAAGAGTGGGAGAGGGCTACGACAGTTTAGCATGAAAGTTTGTGAAAAGGTGGAAAGCAAGGGAAGGACTACTTACAATGAGGTTGCAGATGAACTCGTTGCTGAATTTGCAGATCCCGGGAACAATGGACCATCCCCGGGCCAGCAACAATATGACGAGAAGAACATAAGAAGAAGAGTATATGATGCTCTGAACGTTCTCATGGCGATGGATATCATATCAAAGGATAAAAAGGAGATTCAATGGAAGGGTCTCCCTCGTACCAGCCTAAGCGACATCGAAGAATTAAAGACCGAGCGTCTCGCACTGAGAAACAGGATTGACAAGAAAGCTGCATATCTGCAAGAACTGGAAGAACAATATGTCGGCCTTCAGAACTTGGTACGAAGAAATGGACGGTTATACAGCTCGGGAAACGCTCCAAGCGGTGGCGTCGCTCTTCCCTTTATACTCGTTCAGACTCGTCCTCATGCTACGGTTGAAGTGGAAATATCCGAAGATATGCAGCTTGTGCACTTTGATTTTAACACTTCTCCGTTTGAGCTCCACGATGATAACTTTGTCCTAAAGTCGATGAAGTTCTGTGAGAGGCCACCACCGAGCGACAACAACATTCCGGTCGGTAACAATTTCCCGTCAGGAGATGCCCTCGAAGGCCCTAGCATCGTGCCACCCGAAGCCTTCCATCCTCATTCGCAGCCTCAGCCTCAGCCTCGGCTCATCCCGACGCCACGAGCCGACCCCTCGGGTACTTTACCCTTAAGAGCTCCCGAATCGCCGCCCATCCCAGGGATAATAAAGGCGCGTGTGAAGCCGGAGAGTTGA ATGGGTCTGAAAGACATCGGAGAGACGCTCCCGCCCGGGTTCCGATTCTCCCCCAGCGACCAGGAGCTCGTCTGCCACTACCTCTACAAGAAGATCGCTAACCAACACCTCCCCACCGGAACCCTCGTCGAGATCGACCTCCATACGTGTGAGCCATGGATGCTTCCAGATGTCGCGAAGCTGAACTCGGAGGAGTGGTACTTCTTCAGCTTCCGTGACCGGAAATACGTGACGGGGTTCCGGGCGAACAGGGCCACGGCGAGGGGGTACTGGAAGGCGACGGGGAAGGACCGGCCGGTGGTGGACGCGGCGACGCGGGGGGTGGTGGGAATGAGGAAGACACTGGTTTTCTACAACCACAGAGCTCCCAACGGCGTGAAGACCGGTTGGATACTCCACGAGTTCCGTCTGGAAAACCCTGGATTGCCTCCCAAGGAGGACTGGGTGTTATGCAGAGTGTTCAAAAAATCAAGATCGCCTCCTTGGGAAGGCCCCACGGGGAGACTGATCGCTCCACGGGATGACTCCGGCGAGGCCACTTCTTCTGATGCTCCATTGATCAAGCCCGGTATCGGACACCCAGCTCACCTGACGGCGGCTCCTTCCGGGCCCAAGTGCGAGGAGGACTATGGGTTCCTGCTTGATCTGTGCGACCCCAATGAGATCGGCTTCCGCCACCCGACCATCGGAGACGACAGCAGCTCCGTTTTCATGTGA
Protein Sequence:
- >55817|Micromonas_pusilla_CCMP1545|E2F/DP|55817
MIRVRVASPTAHGCTCTIEYTTEVLRNRYPIRKYESTTLYCRPYVYGNRYEGTKVPSKVRKYLRTHYDTFVRKYEGNKYESTKVFTVSSKALSYECTQLVHVRVHVHIGTTFLRCKFSIFRSEALYKIMQTPTGSTCRYDSSLSLLTKKFVFLLEKAEEGTINLNRAAESLGVQKRRIYDITNVLEGIGLIEKKSKNNIQWKVLPPQSFGLKSGLSTVTEEIRSMQNDEINLDEHIQNMRRSMHVLLEDPAHKGNLFVSEEDIKDFFSFRSETLVAVRAPHGTTLEVPDPDDRMEIPNKRYRIFLKSKGGPVEVFLVSLHDNVSGQSSKEVHFKKSPVDHSLQGAGRATPSPSRVHSSSAATLARASGHAPWTSYEEREIPAILRIAPPISDPDFWFSDDIKEVGIGLNDMYTSAGLSVLLQRSARCRMNAQREWLSSNYGSQGTSTDN*