Gene Details:

• Gene ID: HL.SW.v1.0.G012672.1
• Gene Family: CAMTA Family
• Description: CAMTA Family protein
• Species: Humulus lupulus
• Source: CAMTA family gene from PlantTFDB

Protein Features:

• Pfam:  PF02458
• Gene3D:  G3DSA:3.30.559.10
• PROSITE profile:  PS51437
• SMART:  SM01076
• Pfam:  PF03859
• Gene3D:  G3DSA:2.60.40.10
• Pfam:  PF01833
• SuperFamily:  SSF81296
• Gene3D:  G3DSA:1.25.40.20
• PROSITE profile:  PS50297
• SuperFamily:  SSF48403
• Pfam:  PF12796
• SMART:  SM00248
• PROSITE profile:  PS50088
• SuperFamily:  SSF52540
• SMART:  SM00015
• PROSITE profile:  PS50096
• Pfam:  PF00612
• InterPro:  IPR003480    IPR023213    IPR005559    IPR013783    IPR002909    IPR014756    IPR020683    IPR002110    IPR027417    IPR000048

Annotation Proteins:

• Refseq:  XP_004288193.1  — PREDICTED: calmodulin-binding transcription activator 3-like
• Refseq:  XP_024180163.1  — calmodulin-binding transcription activator 3-like isoform X2
• Swissprot:  Q6NPP4  — CMTA2_ARATH; Calmodulin-binding transcription activator 2
• TrEMBL:  A0A2P6RQI8  — A0A2P6RQI8_ROSCH; Putative transcription factor CG1-CAMTA family
• TrEMBL:  A0A4P1QPC4  — A0A4P1QPC4_LUPAN; Uncharacterized protein
• STRING:  Migut.L00133.1.p  — (Erythranthe guttata)
• STRING:  XP_004288193.1  — (Fragaria vesca)

Gene Ontology:

• GO:0005634  — Cellular Component — nucleus
• GO:0003677  — Molecular Function — DNA binding

Family Introduction:

• The CAMTA family of calmodulin binding transcription factors comprises six members in Arabidopsis (Bouche et al., 2002; Finkler et al., 2007). Each protein includes an IQ domain for calmodulin binding; ankyrin repeats for protein interactions; the TIG domain, which has nonspecific DNA binding activity; and the CG-1 domain, which has specific DNA binding activity. The CG-1 domain recognizes the core consensus sequence, vCGCGb, referred to as the CG-1 element (da Costa e Silva, 1994). This sequence matches the CM2 sequence, CCGCGT, and overlaps the ICEr1 element. Thus, the possibility was raised that one or more of the CAMTA proteins might have a role in regulating CBF2 expression.

Literature:

• CAMTAs: calmodulin-binding transcription activators from plants to human.   DOI:  10.1016/j.febslet.2007.07.051 ;  PMID:  17689537

Sequences: