Gene Details:

• Gene ID: Niben101Scf04267g00014.1
• Gene Family: C2H2 family
• Description: C2H2 family protein
• Species: Nicotiana benthamiana
• Source: C2H2 family gene from PlantTFDB

Protein Features:

• Pfam:  PF10248
• SuperFamily:  SSF103025
• TIGRFAMs:  TIGR03317
• Gene3D:  G3DSA:3.40.50.1010
• SuperFamily:  SSF57667
• PROSITE profile:  PS50157
• Gene3D:  G3DSA:3.30.160.60
• PROSITE pattern:  PS00028
• Pfam:  PF01936
• InterPro:  IPR019376    IPR017703    IPR029060    IPR007087    IPR013087    IPR021139

Annotation Proteins:

• Refseq:  XP_009804392.1  — PREDICTED: Krueppel-related zinc finger protein 1-like isoform X2
• Refseq:  XP_016477869.1  — PREDICTED: transcription factor IIIA-like isoform X2
• Swissprot:  Q84MZ4  — TF3A_ARATH; Transcription factor IIIA
• TrEMBL:  A0A1S4AMJ8  — A0A1S4AMJ8_TOBAC; transcription factor IIIA-like isoform X2
• TrEMBL:  A0A1U7YJY4  — A0A1U7YJY4_NICSY; Krueppel-related zinc finger protein 1-like isoform X2
• STRING:  XP_009804391.1  — (Nicotiana sylvestris)

Gene Ontology:

• GO:0005730  — Cellular Component — nucleolus
• GO:0003700  — Molecular Function — transcription factor activity, sequence-specific DNA binding
• GO:0008097  — Molecular Function — 5S rRNA binding
• GO:0046872  — Molecular Function — metal ion binding
• GO:0080084  — Molecular Function — 5S rDNA binding

Family Introduction:

• Numerous genes encoding the C2H2 zinc-finger domain have been characterized from a wide variety of eukaryotes, including plants. The canonical ZF (zinc finger) sequence (CX2-4CX3FX5LX2HX3-5H) contains two cysteines and two histidines that coordinate a zinc atom, creating a compact nucleic acid-binding domain. The majority of such proteins characterized to date are DNA-binding transcription factors, and many have been shown to play crucial roles in the development of plants, animals and fungi.

Literature:

• AtZFP1, encoding Arabidopsis thaliana C2H2 zinc-finger protein 1, is expressed downstream of photomorphogenic activation.   DOI:  10.1023/a:1006352809700 ;  PMID:  10794528

Sequences: