Gene Details:
- Gene ID: MELO3C002327P1
- Gene Family: C2H2 family
- Description: C2H2 family protein
- Species: Cucumis melo
- Source: C2H2 family gene from PlantTFDB
Protein Features:
- Pfam: PF10248
- SuperFamily: SSF103025
- TIGRFAMs: TIGR03317
- Gene3D: G3DSA:3.40.50.1010
- SuperFamily: SSF57667
- PROSITE profile: PS50157
- Gene3D: G3DSA:3.30.160.60
- PROSITE pattern: PS00028
- Pfam: PF01936
- InterPro: IPR019376 IPR017703 IPR029060 IPR007087 IPR013087 IPR021139
Annotation Proteins:
- Refseq: XP_008439230.1 — PREDICTED: lysine-specific demethylase REF6
- TrEMBL: A0A1S3AXW7 — A0A1S3AXW7_CUCME; lysine-specific demethylase REF6
- STRING: XP_008439230.1 — (Cucumis melo)
Gene Ontology:
- GO:0009741 — Biological Process — response to brassinosteroid
- GO:0009826 — Biological Process — unidimensional cell growth
- GO:0010228 — Biological Process — vegetative to reproductive phase transition of meristem
- GO:0033169 — Biological Process — histone H3-K9 demethylation
- GO:0035067 — Biological Process — negative regulation of histone acetylation
- GO:0040010 — Biological Process — positive regulation of growth rate
- GO:0045815 — Biological Process — positive regulation of gene expression, epigenetic
- GO:0048366 — Biological Process — leaf development
- GO:0005634 — Cellular Component — nucleus
- GO:0003676 — Molecular Function — nucleic acid binding
- GO:0046872 — Molecular Function — metal ion binding
- GO:0071558 — Molecular Function — histone demethylase activity (H3-K27 specific)
Family Introduction:
- Numerous genes encoding the C2H2 zinc-finger domain have been characterized from a wide variety of eukaryotes, including plants. The canonical ZF (zinc finger) sequence (CX2-4CX3FX5LX2HX3-5H) contains two cysteines and two histidines that coordinate a zinc atom, creating a compact nucleic acid-binding domain. The majority of such proteins characterized to date are DNA-binding transcription factors, and many have been shown to play crucial roles in the development of plants, animals and fungi.
Literature:
- AtZFP1, encoding Arabidopsis thaliana C2H2 zinc-finger protein 1, is expressed downstream of photomorphogenic activation. DOI: 10.1023/a:1006352809700 ; PMID: 10794528
Sequences:
CDS Sequence:
- >MELO3C002327P1|Cucumis_melo|C2H2|MELO3C002327P1
ATGGCAGGCACAGCCATGGCCGCGGAGCCGACTCAAGAGGTACTTTCTTGGCTCAAAACCCTACCGTTAGCTCCTGAATATCACCCGACTTTAGCAGAGTTTCAAGATCCAATTTCATATATTTTCAAGATCGAAAAAGAGGCTTCTAAGTTTGGAATCTGTAAAATTGTACCCCCTGTTCCTCCTTCACCGAAGAAAACTGTAATTGTCAATTTCAATAAGTCGCTTGCAGCTCGTGCTGCCCCCTGTTCTGACTCGACTAATTCTAAGTCTCCGCCTACATTCACTACTCGACAACAGCAGATCGGGTTTTGTCCGAGGAAAACACGACCGGTTCAGAAATCAGTGTGGCAGAGTGGTGAGTATTATACATTTCAGCAATTTGAGGCTAAGGCGAAGAACTTTGAGAAAAGTTATTTGAAGAAATGTACGAGGAAAGGAGGGCTTTCGCCTTTGGAAATCGAAACGCTCTATTGGAGGGCAACTTTAGACAAGCCCTTTTCCGTGGAATATGCAAACGATATGCCTGGTTCAGCTTTTGTGCCAGTAAGTGCTAAAATGTTTAGGGAGGCAGGGGAAGGAACAACGCTTGGGGAAACGGCGTGGAACATGAGGGGTGTGTCTAGGGCGAAAGGGTCTCTGTTGAAGTTTATGAAGGAAGAGATTCCTGGAGTTACTTCGCCAATGGTGTATGTTGCCATGATGTTCAGTTGGTTTGCTTGGCATGTGGAAGACCATGACTTGCATAGTTTGAATTATCTGCATATGGGGGCGGGAAAGACATGGTATGGGGTACCTAGAGATGCTGCTGTGGCTTTTGAGGAGGTTGTAAGGGTTCAGGGATACGGAGGAGAAATTAATCCACTTGTAACTTTTGCTGTTCTTGGTGAGAAGACTACTGTGATGTCACCTGAAGTTCTAGTTAGCGCTGGAGTTCCATGTTGCAGGTTAGTACAAAATGCAGGTGAATTTGTTGTCACTTTTCCTCGAGCTTATCATACAGGTTTCAGCCATGGATTTAACTGTGGGGAGGCAGCCAATATTGCAACTCCGGAATGGTTAAACGTTGCTAAAGATGCTGCAATTCGTAGAGCTTCAATCAATTATCCTCCAATGGTCTCTCATTATCAGTTGCTATATGATCTTGCTTTAAGTTCCAGAGCTCCTCTGTGCTCTGGTGCGGAACCAAGAAGTTCACGACTAAAAGATAAAAGGAGGAGTGAAGGAGACACAGTTATAAAAGAGTTATTTGTACAGAATATTGTAGAGAATAACAGCCTGCTGGATAATCTTGGGGGAGGAGCTTCAGTTGTACTTCTTCCCCCAGGTTCTTTAGAATCTATTTATTCGAGACTGCGTGTTGGATCCCACTTGAGGTCAAAACCTAGATTTCCTACTGGTGTTTGCAGTTCTAAGGAAGAAACCAAATCTCCTCAAAGTTTTGATTATGATAATCTCGCACTAGAAAATAGCCCGGGAATTAATCGAGTGAAAGGTTTCTATTCGGCGAATGGGCCATATTCGACTCTATCTGAAAGAAGCACGGACAATTTATGTGCTTCAAGTTCAAGGCCTTTGAATGCCAACAATGAACGAGGTGGTAATGTTCAAAGCAATGGATTATCAGATCAAAGACTGTTTTCTTGTGTCACATGTGGTATTTTAAGTTTTGCCTGTGTAGCCATCATCCAACCCAGAGAACAAGCTGCTAGGTACCTTATGTCAGCTGACTGTAGCTTCTTCAATGATTGGGTTGTTGGTTCCGGGATAGCCAGTGAAGGGATTTCTACTAAAGATCGGCATCCAGTTAGCTCTCAGCAGATTAGTAATAGTGGAAAAAGAGATAAGTGTGTCTCTGATGGATTGTATGACATCCCAGTCCTGGCTGTCAATCGACAGCTTCAGTTAGCAGGCAAAAGTTATGAAGCAGATTTAAATACTGAAAAACGAAATGAGACTTCTGCCCTTGGCATGCTTGCATTGACTTACGGACATTCTTCTGATTCTGAGGACGACAATGCTGAAGCAGATGCTGTTTTAAATGTGGATGATGCTAAACTAATGATTTGTTCTTCAGAAGAACAATATCAGTTTGAAAATTCTGGCCTTACTTCTAGTGAATATAGCAAGAACACTGCAATTTTGAATCACGACCCCTCGTCATTTGGTGTTAACTCTGCAGATCATATGCAATTTCAAGTCAACGACTATGAAGAATTTCGACGAGCTGATTCCAAAGACTCGTTCAATTGTTCTTCTGAGTCTGAAATGGATGGCATAGGTTCAACCAAGAAAAATGGTTTGTCAACTAGATATCAAGATTCTCATGTGAATGGCAGATCTTCCTTAGACGCTGATACTGAAAAACCAGTGTTTGACAAGTCCACTGAAACAGTCGAGACTGAGAATATGCCATTTGCTCCAGATATCGATGAAGACTCCTCTAGATTGCATGTATTTTGTCTAGAGCATGCAAAAGAAGTGGAACAACAACTTCGACCAATTGGAGGAGTGCACATTCTTTTACTTTGTCATCCAGTTTCTTCTGACTATTATGCCAAACTTGAAAATTTTGCTGCATCTAACATTGCCTGCTTCATGAAAAATTTGTTAGACTATCCGAAGATGGAGGCAGAAGCAAAACTGGTGGCACAAGAATTAAGTATGAGCCATCTGTGGACTGATACGATATTCAGAGATGCCACCCAAGATGAAGAAAAGAGGATTCAGTTAGCTTTAGATTGCGAGGAAGCAATTCCGGGTAATGGAGATTGGGCTGTAAAATTGGGAATAAATCTCTTTTATAGTGCCAACCTTAGTCACTCTCCTCTATATAGTAAGCAGATGCCATACAACTCTGTTATTTATAATGCATTTGGCCGTAGTACTTCTGCCAACTCTTCTGGTAAGCCAAAAGTCTATCAAAGGAGGACTGGAAAGTTGAAAAGAGTAGTTGCAGGGAAATGGTGTGGGAAAGTCTGGATGTCCAATCAAGTCCATCCTTTGCTGGCGAAGAGAGATCCTCAAGAAGAAGATGTAGACATCTTTCCTTCTTGGACAATGTCAGATGAGAAGGTTGATAGGAAATCAGCAAATATCCAGAAAATTGAGACTGTTAAGGTAAATAGAAAGTCTGCTGGCAAGAGAAAAATGAATTATGGGCGTGGAACAACTAAGAAAGCCAAACTTGTAGAGTCAGAGGACATGGTTTCAGATGCTTCAGTTGAAGATTGTATCCATCGGCATCATAGTATTCTACGGAACAAGCAATGCAAATTTGTTGAGAGCAATGATCCAATGTCGGATGATTCTGTGGAGGATGATTCTTCTAGAAAACATGGAGTTCCCGTCAGCAAGGGAACGCCATATTTTGTTACAGATGATACCGGTTCAGATGATTCTCTTGGAGATCGTCATACTCCGCACAGAGGGTTCTCTGGATTCAAGCTGCCCAGATGGGGTGAGATAGAACCTTCAGTTTCTGATGATTCCTTAGAGCACTATTCTTCTCAGCATCGTGGGAAAAATATTAAAAGCAGGACAGAAAAATACATTGAGAGACAAGATACACTTTCAGATGAGTGTCTGGAGAGTGGCTCTCTTAAGCAATATAGAAGAATTCCGAAAAGCAAACAAACCAAAGTTTTTAAAAAGAATGCCATTTCACACGATATACGAGATGATAGTTTTCTTTGGCATCATCAAAGGCCCTCCAGAATCAAGAAGGCCAAATTTATTGAGAGTGAAGATGCAGTTTCAGAGCACTCACTAGAAAACAATTCTCATCAGCATAGAAGTATGCCTCAAATAAAACCAGCCAAGCACACTGCGTGGGAAGATGCATTTTCAGATGGTCCAGATGAAGATGATAATTCTCTTCTGCATCATCGGAATGTTAGAAGTAACATGCAATTCAGAGAAATTACATCAGACGATCAGCTTGATGATAGTGCTAATCAATGCAGTAGGAGGGTACTCCGGAGGAAGCCGGTTAAGACAGAGACAATTTCGCAAATGAAACAAGAGATCCTGCGACCTGCAAAGCGAGGAGCCTCTCAGACTTTGAAAGAAGAATTTGCTCAATCTTTAAAACGTGGAGGCCGCCATTCATTAAAATTAGAGACCCCTCAGCCAAAAATACAGCATGCCACAAATCGACGTGGTAAGCAAACTAAGAGGAATGGAAAATCGACTGATTTAGAATCAGAAGAAGATCAACTAGGTGGACCTAGTACACGTCTTAGAAAAAGAACTCCAAAACCTACTCAACTTTCAGAAGCAAAAGTGAAAGATAAAAAACCAGTTGCCAAGAAAAAGATGAAAACTGGTTCATCTTTGAAGACTCCAGCAGGCCATAGAGATTCAAAAGCAAGGGATGAGGAATCAGAATATCTTTGTGACATCGAGGGTTGCAATATGAGTTTTGGTACAAAACAAGAACTTGCCTTACACAAACGAAATATCTGTCCTGTCAAGGGGTGTGTGAAGAAGTTTTTCTCACATAAGTACCTTGTGCAGCACCGTCGAGTCCACATGGACGACCGTCCCCTCAAATGTCCATGGAAGGGCTGCAAGATGACTTTCAAATGGGCATGGGCACGAACAGAACATATTCGTGTCCATACAGGTGCTCGACCTTATGTTTGCGCTGAACCTGGATGTGGTCAGACATTCAGATTTGTTTCGGATTTCAGTCGTCACAAGCGGAAGACTGGACATTCGACAAAGAAAGGTAGAGGTTAA
Protein Sequence:
- >MELO3C002327P1|Cucumis_melo|C2H2|MELO3C002327P1
MAGTAMAAEPTQEVLSWLKTLPLAPEYHPTLAEFQDPISYIFKIEKEASKFGICKIVPPVPPSPKKTVIVNFNKSLAARAAPCSDSTNSKSPPTFTTRQQQIGFCPRKTRPVQKSVWQSGEYYTFQQFEAKAKNFEKSYLKKCTRKGGLSPLEIETLYWRATLDKPFSVEYANDMPGSAFVPVSAKMFREAGEGTTLGETAWNMRGVSRAKGSLLKFMKEEIPGVTSPMVYVAMMFSWFAWHVEDHDLHSLNYLHMGAGKTWYGVPRDAAVAFEEVVRVQGYGGEINPLVTFAVLGEKTTVMSPEVLVSAGVPCCRLVQNAGEFVVTFPRAYHTGFSHGFNCGEAANIATPEWLNVAKDAAIRRASINYPPMVSHYQLLYDLALSSRAPLCSGAEPRSSRLKDKRRSEGDTVIKELFVQNIVENNSLLDNLGGGASVVLLPPGSLESIYSRLRVGSHLRSKPRFPTGVCSSKEETKSPQSFDYDNLALENSPGINRVKGFYSANGPYSTLSERSTDNLCASSSRPLNANNERGGNVQSNGLSDQRLFSCVTCGILSFACVAIIQPREQAARYLMSADCSFFNDWVVGSGIASEGISTKDRHPVSSQQISNSGKRDKCVSDGLYDIPVLAVNRQLQLAGKSYEADLNTEKRNETSALGMLALTYGHSSDSEDDNAEADAVLNVDDAKLMICSSEEQYQFENSGLTSSEYSKNTAILNHDPSSFGVNSADHMQFQVNDYEEFRRADSKDSFNCSSESEMDGIGSTKKNGLSTRYQDSHVNGRSSLDADTEKPVFDKSTETVETENMPFAPDIDEDSSRLHVFCLEHAKEVEQQLRPIGGVHILLLCHPVSSDYYAKLENFAASNIACFMKNLLDYPKMEAEAKLVAQELSMSHLWTDTIFRDATQDEEKRIQLALDCEEAIPGNGDWAVKLGINLFYSANLSHSPLYSKQMPYNSVIYNAFGRSTSANSSGKPKVYQRRTGKLKRVVAGKWCGKVWMSNQVHPLLAKRDPQEEDVDIFPSWTMSDEKVDRKSANIQKIETVKVNRKSAGKRKMNYGRGTTKKAKLVESEDMVSDASVEDCIHRHHSILRNKQCKFVESNDPMSDDSVEDDSSRKHGVPVSKGTPYFVTDDTGSDDSLGDRHTPHRGFSGFKLPRWGEIEPSVSDDSLEHYSSQHRGKNIKSRTEKYIERQDTLSDECLESGSLKQYRRIPKSKQTKVFKKNAISHDIRDDSFLWHHQRPSRIKKAKFIESEDAVSEHSLENNSHQHRSMPQIKPAKHTAWEDAFSDGPDEDDNSLLHHRNVRSNMQFREITSDDQLDDSANQCSRRVLRRKPVKTETISQMKQEILRPAKRGASQTLKEEFAQSLKRGGRHSLKLETPQPKIQHATNRRGKQTKRNGKSTDLESEEDQLGGPSTRLRKRTPKPTQLSEAKVKDKKPVAKKKMKTGSSLKTPAGHRDSKARDEESEYLCDIEGCNMSFGTKQELALHKRNICPVKGCVKKFFSHKYLVQHRRVHMDDRPLKCPWKGCKMTFKWAWARTEHIRVHTGARPYVCAEPGCGQTFRFVSDFSRHKRKTGHSTKKGRG*