Gene Details:

  • Gene ID: XP_004498682.1
  • Gene Family: bZIP Family
  • Description: bZIP Family protein
  • Species: Cicer arietinum
  • Source: bZIP family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  XP_004498677.1  — transcription factor TGA2.2 isoform X2
  • Refseq:  XP_012570693.1  — transcription factor TGA2.2 isoform X2
  • Refseq:  XP_027189523.1  — transcription factor TGA2.2 isoform X3
  • Refseq:  XP_027189524.1  — transcription factor TGA2.2 isoform X5
  • Refseq:  XP_027189525.1  — transcription factor TGA2.2 isoform X6
  • Refseq:  XP_027189526.1  — transcription factor TGA2.2 isoform X7
  • Refseq:  XP_027189527.1  — transcription factor TGA2.2 isoform X7
  • Swissprot:  Q41558  — HBP1C_WHEAT; Transcription factor HBP-1b(c1) (Fragment)
  • TrEMBL:  A0A1S2Y3E3  — A0A1S2Y3E3_CICAR; transcription factor TGA2.2 isoform X7
  • TrEMBL:  A0A1S3E5J4  — A0A1S3E5J4_CICAR; transcription factor TGA2.2 isoform X2
  • TrEMBL:  A0A3Q7X792  — A0A3Q7X792_CICAR; transcription factor TGA2.2 isoform X5
  • TrEMBL:  A0A3Q7XQ84  — A0A3Q7XQ84_CICAR; transcription factor TGA2.2 isoform X3
  • TrEMBL:  A0A3Q7YEW3  — A0A3Q7YEW3_CICAR; transcription factor TGA2.2 isoform X6
  • STRING:  XP_004498676.1  — (Cicer arietinum)

Gene Ontology:

  • GO:0006355  — Biological Process — regulation of transcription, DNA-templated
  • GO:0003700  — Molecular Function — transcription factor activity, sequence-specific DNA binding
  • GO:0043565  — Molecular Function — sequence-specific DNA binding

Family Introduction:

  • The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
  • Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Literature:

Sequences:

CDS Sequence:
  • >XP_004498682.1|Cicer_arietinum|bZIP|XP_004498682.1
    ATGGCTGAAGGAAGTCCTATAACTGATATTTCTACTGATGGTGACACCGATGATAAGAATCAACGGTTTGATAGAAGTCGGTCCCTTGCTGCAATGGCTTCTGACTCCGGTGACAGATCAAAGAATAAATCAGATCAAAAGACTCTCCGCAGGCTTGCTCAGAATCGTGAGGCTGCAAGAAAAAGCCGGTTGAGAAAGAAAGCTTATGTCCAACAGTTGGAAAGTAGCCGTTTGAAGTTCACTCAACTGGAGCAAGAGCTTCAGCGAGCTCGGCAACAGGGAATCTTTATATCAAGCTCAGGCGATCAAGCACACTCAATGAGTGGAAATGGGGCCATGGCATTTGATGTAGAATATGCAAGGTGGCTGGAAGAGCAGAATCGACAAATTAATGAGCTAAGAGGAGCTGTAAATTCTCATGCGAGCGAAACAGAACTTCACATGATAATGGATGGTATATTGGCACATTATGATGAGATATTTAGACTTAAGGGCATTGCAGCTAAGGCTGATGTCTTCCATTTGTTGTCTGGCATGTGGAAAACACCAGCTGAGAGGTGTTTTCTATGGCTTGGTGGTTTTCGATCGTCTGAACTCCTCAAGCTTCTGATAAATCAATTGGAACCTCTCACAGATCAGCAGCTAGTAGGCATTACAAACTTGCAACAATCTTCGCAAGAGGCGGAAGACGCATTGTCTCAGGGCATGGAAGCATTGCAACAGTCCCTTTCTGAGACATTAACTACTGGACCACTTGGGTCCTCTAGTTCATCAGGGAATGTGGCAAATTACATGGGTCAGATGGCTATGGCCATGGGTAAGCTAGGGACACTTGAGGGGTTTATTCGACAGGCCGACAACTTGCGGCAACAAACACTGCAACAAATTCACCGCATATTGACCACTCGCCAGTCAGCTCGCGCGCTCCTTGCAATTCACGACTACTTTTCCAGATTGCGTGCTCTTAGCTCCCTTTGGCTTGCGCGTCCAAGAGAATGA
Protein Sequence:
  • >XP_004498682.1|Cicer_arietinum|bZIP|XP_004498682.1
    MAEGSPITDISTDGDTDDKNQRFDRSRSLAAMASDSGDRSKNKSDQKTLRRLAQNREAARKSRLRKKAYVQQLESSRLKFTQLEQELQRARQQGIFISSSGDQAHSMSGNGAMAFDVEYARWLEEQNRQINELRGAVNSHASETELHMIMDGILAHYDEIFRLKGIAAKADVFHLLSGMWKTPAERCFLWLGGFRSSELLKLLINQLEPLTDQQLVGITNLQQSSQEAEDALSQGMEALQQSLSETLTTGPLGSSSSSGNVANYMGQMAMAMGKLGTLEGFIRQADNLRQQTLQQIHRILTTRQSARALLAIHDYFSRLRALSSLWLARPRE