Gene Details:

  • Gene ID: Tp2g05460
  • Gene Family: bZIP Family
  • Description: bZIP Family protein
  • Species: Thellungiella parvula
  • Source: bZIP family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  XP_002888232.2  — uncharacterized protein At4g06598 isoform X1
  • Refseq:  XP_020891575.1  — uncharacterized protein At4g06598 isoform X2
  • Refseq:  XP_020891576.1  — uncharacterized protein At4g06598 isoform X3
  • TrEMBL:  D7KY87  — D7KY87_ARALL; Predicted protein
  • STRING:  Al_scaffold_0002_682  — (Arabidopsis lyrata)

Family Introduction:

  • The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
  • Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Literature:

Sequences:

CDS Sequence:
  • >Tp2g05460|Thellungiella_parvula|bZIP|Tp2g05460
    ATGTCTGGCTCCAAGGGATCAGAGAGTGTTAGGAATCTGATGTACCCAGGAAAAAATGCTTTGCTCCCTCCGAAAATCCCGTTTCCTAGCGTGTCAGCTTCGTATTCAGAGTACATTCCCTGTGGTTTGAAGGGTTCAAGGCACGGTCAGAGGCTTAGTGATGAGAAAACGCACCACCAACGGACTTCCTCAGAGAGCCATTTGGTAGAAGAGCTTCCCTTTTGGCTTGATGATCTTCTCAATGAGCCAGAGAGCCCTGCTCGCAGATGCGGTCATAGGCGTTCATCAAGTGACTCTTACGCTTACCTAGATGTGGCTAATGCTACAAACATAAGTTTGACTCTCCAAAATGATTTCAGTTATAGGAATACGGTTGCTTCCACTCAAAGAGGAATTCAAGAGCTTGATCGGAGTAAAAATGCTCAGGCCGCCGCCTTTTACACTGATGTTAATTTTCTAAAACAGAAGAATCTACAGCGGGATTCTTTGGTGGCATCCGGTGTTCGTCCTTGTCTGCTACCTTCTGCTCGAGAGAGTGTTGGTGGGAAAAACATGGGAGCATCATATATGCCTCAAGAAGCAACAGCAGAAACAAAGAACTACGCAGAAACTCTTTCTCATGATCTTAAAAGGTTCTCTTCTGAGGAAAACAATTCTAATGCTCAGCCTGTGACGTATGAAGCTGAGAATATAAAACGTGCCAAACAGCAATTTGCACAACGATCACGCGTCCGTAAACTCCAGTACATATCTGAGCTAGAAAGAAATGTACAAACATTGCAGGCAGAAGGCTCCAAAGTTACAGCTGAGCTTGATTTTCTTAACCAGCGGAGTCTTATTCTGAGTTTGGAAAATAAAGCTCTTGAGCGCCGCCTCGAAAGTATATCTCAGGAGAAGCTGATCAAACAATTGGAACAAGAGGTGCTGGAAAATGAGATTGAAAGACTACGAGCTCTGTATCAACAACAACAACAAACTTATAAACCATCAGCAACTCACGGACGTGCTACTAGCAAAGATCTCGAATCTCAGTTCTCGAGTCTTTCCCTGAACACTAAAGATTCTAACTATAGGCGTGACTCTGTATCTGTGTTGGGTCAACTCCACTTTTAG
Protein Sequence:
  • >Tp2g05460|Thellungiella_parvula|bZIP|Tp2g05460
    MSGSKGSESVRNLMYPGKNALLPPKIPFPSVSASYSEYIPCGLKGSRHGQRLSDEKTHHQRTSSESHLVEELPFWLDDLLNEPESPARRCGHRRSSSDSYAYLDVANATNISLTLQNDFSYRNTVASTQRGIQELDRSKNAQAAAFYTDVNFLKQKNLQRDSLVASGVRPCLLPSARESVGGKNMGASYMPQEATAETKNYAETLSHDLKRFSSEENNSNAQPVTYEAENIKRAKQQFAQRSRVRKLQYISELERNVQTLQAEGSKVTAELDFLNQRSLILSLENKALERRLESISQEKLIKQLEQEVLENEIERLRALYQQQQQTYKPSATHGRATSKDLESQFSSLSLNTKDSNYRRDSVSVLGQLHF