Information report for Spipo11G0044300
Gene Details
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Functional Annotation
- Refseq: XP_012084427.1 — transcription factor RF2a
- TrEMBL: A0A1D1ZEL4 — A0A1D1ZEL4_9ARAE; Transcription factor RF2b (Fragment)
- STRING: XP_006471421.1 — (Citrus sinensis)
- STRING: XP_006487269.1 — (Citrus sinensis)
- STRING: XP_006493636.1 — (Citrus sinensis)
- GO:0006355 — Biological Process — regulation of transcription, DNA-templated
- GO:0005634 — Cellular Component — nucleus
- GO:0005829 — Cellular Component — cytosol
- GO:0003700 — Molecular Function — transcription factor activity, sequence-specific DNA binding
- GO:0043565 — Molecular Function — sequence-specific DNA binding
Family Introduction
- The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
- Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.
Literature and News
Gene Resources
Sequences
CDS Sequence:
- >Spipo11G0044300|Spirodela_polyrhiza|bZIP|Spipo11G0044300
ATGGAGCCGTGTGAGGAAGCCCGTAACGATCTGATGCAGCGGCTTCAGTCTTCAATGGCGACGTCGTCGTCATCTCTGCCTAAGCAGCAGGATCAGAATCCCTCCAATCAGATGCAGCAGCAGGCGCCGCCACTGCCACCGCCGGGACAGCATCCCTTCGGCAGTCGATTTGATCTACTCCATGTGTACCGTTCTGGTTCCCCTCTCCACCATTTCTCCGGCAACTTTGGAAGCCTCGAGAAAACCAGCGCCACACCATCTGCCCACAGTGGCGGCGGTGGTAATAATATGACCTCCGTCGGCAACACCAGCAAACGGCCGGCAGGTATTCCCCCAACCTCTCCTTACTCCCAGACGTTACCCACTGCCTCCGCCCGATCTCCGACTCAGCAGTCAGGCCTACAGAGTTTCGGTCATGGTCCGTTCCACACCAGATCTTTATCCCAGCCAGCCTCGCTCTACTCCCCGGACTTGTTGCCTCCACTCAGTCCCTCGCAGTACCGTGATTCACCATCTGCCACCGTCGTCTACGACCCAATGTCCACAGATACACCCACCGAAAACAGAGATATCAAGTGTCAATCAACCACGCCCCCTCCCGGAACTTTCTCTAGGTCCAATCCAAGTCGGACGGGCGACGCTCTCCCACCTCGGAAGGCCCACCGGCGCTCGCATAGTGATATCCCCTTCGGATTTTCCCAGGGTTCTTTCTCCTCTGCCTTCCCTCCTTTGACCCAGAGGCCACAAGGGGGGTATCTTGAGAGATGCTTGTCTGTGGTGGATAATGCCGGCTCAGTCGGCAAGCAGGTAGAGGGACAGTTCGTGAAGCAGGAATTAGACTGGGATCGGGATTTGGACAGCAGTGCAGAAGGCACGGTGGAGCGGAAGTCAGAAGGGGATGCTGGGGACGACCTGTTTAGTGCTTTCATGAACTTGGATAATCTCGATGCCCTCAACTCCTCTGGAACTGAAGACAAACGTGAAGATATGGACAGCAGGGCCAGTGGCACTAAAACAAATGGTGCTGACAGCAGCGAGAATGAAGCTGAGAGCAGCGTCAATGAGGGTGGCGGTAGAGTACTACCGCAAAAGGTGAAGACCTCTCCCTCGTTAGAGAAGGAGGGATCAAAACGAAGTGCTGCTGGAGATCCTGATTTGAATGTCAGTGCTTCAAGACATTCCCGAAGTATTTCAATGGATAGCTTCATGGAGAAGATGAATTTTGGGGATGAGTCGCCAAAACTGCCTCCATGTCCGGGAGCTAGGCCGGGGCAGGATTCGTACACCAATTCCTTGGACGGAACTTCCAGTAATTTCAGTTTGGACTTGGCTAATGGAGAATTTAGTGGGGTAGAACTTAAGAAGATAATGGCAAATGAGAAGCTCGCTGAGATTGCCTTAACTGATCCAAAACGTGCTAAGAGGATATTAGCCAACCGGCAGTCAGCTGCTCGGTCAAAGGAACGCAAATTGAGATACATCTCAGAATTAGAACACAAGGTGCAGATTCTGCAGACAGAAGCTACTACTTTGTCTGCACAGCTTACTATGTTACAGAGAGACTCATCAGATCTGACCAGTCAAAATAATGAGCTCAAATTTCGTCTTCAGGCCATGGAACAACAGGCACGGCTTAGAGATGCTCTGAACGAGGCCCTGACCGGGGAGGTCCAGAGGCTGAAACTCGCCACCCGAGAGATGGCTGATGGGAACCCACCTGGTAACCTGAACCAGCACCTCTCGTTGAACCCTCAGCTCTTCCAGCTACACCAGCATCAGCAGCACCAGCAGTCCACCCAGCTGCCCATCTATCAACTACAGCGCCAGCAGCAGCAGCAGCAGCAGCAGCAGCATCAGCAGCATCAGCAGCATCAGCAGGAGCAGAATCATCAGAAGCAGCAGCAGGAGAGCTCTCCTGCGGCAAAATGTGAAGCAAACTAG
Protein Sequence:
- >Spipo11G0044300|Spirodela_polyrhiza|bZIP|Spipo11G0044300
MEPCEEARNDLMQRLQSSMATSSSSLPKQQDQNPSNQMQQQAPPLPPPGQHPFGSRFDLLHVYRSGSPLHHFSGNFGSLEKTSATPSAHSGGGGNNMTSVGNTSKRPAGIPPTSPYSQTLPTASARSPTQQSGLQSFGHGPFHTRSLSQPASLYSPDLLPPLSPSQYRDSPSATVVYDPMSTDTPTENRDIKCQSTTPPPGTFSRSNPSRTGDALPPRKAHRRSHSDIPFGFSQGSFSSAFPPLTQRPQGGYLERCLSVVDNAGSVGKQVEGQFVKQELDWDRDLDSSAEGTVERKSEGDAGDDLFSAFMNLDNLDALNSSGTEDKREDMDSRASGTKTNGADSSENEAESSVNEGGGRVLPQKVKTSPSLEKEGSKRSAAGDPDLNVSASRHSRSISMDSFMEKMNFGDESPKLPPCPGARPGQDSYTNSLDGTSSNFSLDLANGEFSGVELKKIMANEKLAEIALTDPKRAKRILANRQSAARSKERKLRYISELEHKVQILQTEATTLSAQLTMLQRDSSDLTSQNNELKFRLQAMEQQARLRDALNEALTGEVQRLKLATREMADGNPPGNLNQHLSLNPQLFQLHQHQQHQQSTQLPIYQLQRQQQQQQQQQHQQHQQHQQEQNHQKQQQESSPAAKCEAN*