Gene Details:

  • Gene ID: Sobic.003G329500.2.p
  • Gene Name: Sb03g037560, SORBIDRAFT_03g037560
  • Gene Family: bZIP Family
  • Description: bZIP Family protein
  • Species: Sorghum bicolor
  • Source: bZIP family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  XP_002458658.1  — transcription factor TGAL1
  • Swissprot:  Q41558  — HBP1C_WHEAT; Transcription factor HBP-1b(c1) (Fragment)
  • TrEMBL:  C5XMK2  — C5XMK2_SORBI; Uncharacterized protein
  • STRING:  Sb03g037560.1  — (Sorghum bicolor)

Gene Ontology:

  • GO:0009410  — Biological Process — response to xenobiotic stimulus
  • GO:0009627  — Biological Process — systemic acquired resistance
  • GO:0045892  — Biological Process — negative regulation of transcription, DNA-templated
  • GO:0045893  — Biological Process — positive regulation of transcription, DNA-templated
  • GO:0005634  — Cellular Component — nucleus
  • GO:0005737  — Cellular Component — cytoplasm
  • GO:0003700  — Molecular Function — transcription factor activity, sequence-specific DNA binding
  • GO:0043565  — Molecular Function — sequence-specific DNA binding

Family Introduction:

  • The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
  • Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Literature:

Sequences:

CDS Sequence:
  • >Sobic.003G329500.2.p|Sorghum_bicolor|bZIP|Sobic.003G329500.2.p
    ATGGAGAGTAGACGAGGAGGGTCGACGGCGGCGGCGGAAGATGCGGGCGGGGGGATGCCGAGCTTTGGGCCACCTCAGCACGCCATCCACACAGATGTGAACAGCATGCAACCTTCTCGAGTTACCGACTTTGGGGCACTTGCGCAGTCAGCTGGATTCCGAATAGAAGATCTTGCTAACCTCAATGCAAATGCTTTGTTCAATCTGAAGCCAAATACCCATACAATTAACAACAGTCCTCTTCAGTTTGGAAGTTACGGGAAGCCTATTTCTCCTCACATAAATACTATAGAAGCAGCAACAGCTAAAACAAGAATTGACCCTCAGTTGCTAGAACAGCAAACAGGAGCACAATCAAATCTGGTGGCATTACCAACTGGTAACATCGAGAATTGGGGAGAGTCAGCTATGGCTGGTGGTAGCCCTATGACTGACACATCTTCAGATCCAGACACTGATGAGAGGAACCAGATGTTTGAACAAGGCCTGGTTACTGTCCCCACAGCTTCTGATTCTAGTGACAAATCAAGGGACAAACTAGATCAGAAGACACTTCGGCGTCTTGCCCAAAATCGTGAAGCTGCCAGGAAAAGCCGTTTACGAAAGAAGGCATACATCCAAAACCTTGAGAGTAGCAGACTGAAACTTACTCAGTTAGAGCAAGAGCTTCAGCGGGCTCGTCAACAGGGTATTTTTATTTCGACATCAGGAGATCAACCTCAATCAACAAGTGGAAATGGAGCTTTGGCATTTGACATGGAGTATGCACGCTGGTTGGAGGAGCACAACAAACATGTAAATGAGTTGAGGGCTGCTGTCAATGCACATGCCGGTGATAATGATCTTCGTGGTATTGTTGATAGCATTATGGCACACTACGACGAAATTTTCAGGCTCAAGGGTGTGGCAGCTAAAGCAGATGTTTTTCATGTGCTGTCTGGGATGTGGAAGACCCCTGCTGAGAGATGTTTCATGTGGTTAGGTGGCTTCCGATCATCTGAGCTTCTTAAGTTACTGGCAGGTCACCTAGAGCCTCTTACTGATCAGCAGCTTGTTGGTATATCCAACCTGCAACAGTCCTCCCAGCAAGCTGAAGATGCTCTTTCTCAAGGGATGGAAGCGTTACAACAGTCGCTTGCAGAAACTCTAGCATCTGGATCCCTGGGCCCTGCTGGACCTTCTGGCAATGTTGCAAATTACATGGGACAAATGGCAATGGCTATGGGAAAACTTGGCACCCTTGAGAACTTTCTACGGCAGGCTGATAATCTACGGCTGCAAACACTTCAACAAATGCAACGCATATTAACCACCCGACAATCAGCACGAGCCCTACTTGCAATAAGCGACTACTTCTCTCGGCTGCGTGCTTTGAGCTCTCTTTGGCTTGCCCGTCCAAGGGAATAA
Protein Sequence:
  • >Sobic.003G329500.2.p|Sorghum_bicolor|bZIP|Sobic.003G329500.2.p
    MESRRGGSTAAAEDAGGGMPSFGPPQHAIHTDVNSMQPSRVTDFGALAQSAGFRIEDLANLNANALFNLKPNTHTINNSPLQFGSYGKPISPHINTIEAATAKTRIDPQLLEQQTGAQSNLVALPTGNIENWGESAMAGGSPMTDTSSDPDTDERNQMFEQGLVTVPTASDSSDKSRDKLDQKTLRRLAQNREAARKSRLRKKAYIQNLESSRLKLTQLEQELQRARQQGIFISTSGDQPQSTSGNGALAFDMEYARWLEEHNKHVNELRAAVNAHAGDNDLRGIVDSIMAHYDEIFRLKGVAAKADVFHVLSGMWKTPAERCFMWLGGFRSSELLKLLAGHLEPLTDQQLVGISNLQQSSQQAEDALSQGMEALQQSLAETLASGSLGPAGPSGNVANYMGQMAMAMGKLGTLENFLRQADNLRLQTLQQMQRILTTRQSARALLAISDYFSRLRALSSLWLARPRE*