Gene Details:
- Gene ID: PGSC0003DMP400000201
- Gene Name: LOC102597029
- Gene Family: bZIP Family
- Description: bZIP Family protein
- Species: Solanum tuberosum
- Source: bZIP family gene from PlantTFDB
Protein Features:
- SMART: SM00338
- Gene3D: G3DSA:1.20.5.170
- PROSITE profile: PS50217
- Pfam: PF00170
- SuperFamily: SSF57959
- PROSITE pattern: PS00036
- InterPro: IPR004827
Annotation Proteins:
- Refseq: XP_006339668.1 — PREDICTED: transcriptional activator TAF-1-like
- Swissprot: Q99142 — TAF1_TOBAC; Transcriptional activator TAF-1 (Fragment)
- TrEMBL: M0ZGE8 — M0ZGE8_SOLTU; Uncharacterized protein
- STRING: PGSC0003DMT400000266 — (Solanum tuberosum)
Gene Ontology:
- GO:0006355 — Biological Process — regulation of transcription, DNA-templated
- GO:0009737 — Biological Process — response to abscisic acid
- GO:0005829 — Cellular Component — cytosol
- GO:0003700 — Molecular Function — transcription factor activity, sequence-specific DNA binding
- GO:0043565 — Molecular Function — sequence-specific DNA binding
- GO:0044212 — Molecular Function — transcription regulatory region DNA binding
Family Introduction:
- The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
- Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.
Literature:
Sequences:
CDS Sequence:
- >PGSC0003DMP400000201|Solanum_tuberosum|bZIP|PGSC0003DMP400000201
ATGGGAAACAGTGAGGATGGGAAATCCTGTAAGCTTGAGAAACCATCCTCGCCTGCACCGGACCAGAGCAATCTCCATGTCTATCCGGATTGGGCAGCCATGCAGGCATATTATGGTCCTCGAGTAGCTGTACCTGCATATTTCAATTCAGCAGTTGCACCTGGTCATACCCCCCACCCCTATATGTGGGGGCCACAGCCTATGGTACCACCTTATGGTGCCCCTTATGCAGCAATATATGCTCATGGTGGGGTTTATGCACATCCTGGAGTTCCAATTGGATCTCATCCTCCAGGTCATGTGATTGCGACATCTCCTGTTGTCAGCCAAGCCATGGATGGTGCTTCTTTGAGTTTAGATGCGTCTGCCAAGTCCTTGGGAAATTCTGATCGAGGCTTGATGACTAAACTGAAGGAATTTGAGGGGCTGGCAATGTCACTTGGAAATGGCAGCACTGACAATGTTGAGGGTGGAACAGACAATGGACATTCTCAAAGTGGGGAAACTGAAGGTTCAACTGATGGAAGTGACACAAATGGAGCTGGGGTCAGTGAGAGAAGTAAGAAAAGGAGCTGTGAGACAACTCCTGATAACTCTGGTGATGATAAGAGTCACTCACGAAGATGTCAACCTTCTGGGGAAGTAAATGATGATGGTGAGAAGTCAATCGTTATTGCAGCGAAAATGACGGGAACAGTACTTTCTCCTTGCATGACAACTTTGGAAATGAGAAATCCTGCCAGTGCACATATGAAATCTAGCCCAACTAATGGTTCACCACTCAGCCCTGCACTGCCTAATGAAACCTGGTTACAGAATGAGCGTGAGCTGAAGCGGGAGAAAAGGAAACAGTCTAATCGGGAATCTGCAAGGCGATCGAGATTGAGAAAACAGGCTGAAGCTGAAGAATTGTCAATACGAGTTCAGGCTTTAACAGGAGAGAACTTGACACTCAGATCCGAGATTAACAAATTAATGGAGAACTCGGAGAAACTGAAGCTAGATAATGCTGCTTTAATGGAGAGACTGAAAAATGAAGAGCTAGGACAGACAGAAGAAGTGAGTTTAGGTAAGATTGCTGATAAGAGACTGCAACCTGTAGGCACAGTAAACCTGCTAGCAAGAGTGAACAACTCAGGTTCCTCGGATACAACAAACGAGGAGGGTGAAGTTTATGAGAACAACAGCTCTGGAGCAAAGCTTCATCAACTACTTGATACCAGCCCCAGAAGTGATGCAGTAGCAGCTGGTTGA
Protein Sequence:
- >PGSC0003DMP400000201|Solanum_tuberosum|bZIP|PGSC0003DMP400000201
MGNSEDGKSCKLEKPSSPAPDQSNLHVYPDWAAMQAYYGPRVAVPAYFNSAVAPGHTPHPYMWGPQPMVPPYGAPYAAIYAHGGVYAHPGVPIGSHPPGHVIATSPVVSQAMDGASLSLDASAKSLGNSDRGLMTKLKEFEGLAMSLGNGSTDNVEGGTDNGHSQSGETEGSTDGSDTNGAGVSERSKKRSCETTPDNSGDDKSHSRRCQPSGEVNDDGEKSIVIAAKMTGTVLSPCMTTLEMRNPASAHMKSSPTNGSPLSPALPNETWLQNERELKREKRKQSNRESARRSRLRKQAEAEELSIRVQALTGENLTLRSEINKLMENSEKLKLDNAALMERLKNEELGQTEEVSLGKIADKRLQPVGTVNLLARVNNSGSSDTTNEEGEVYENNSSGAKLHQLLDTSPRSDAVAAG*