Information report for Pgl009389
Gene Details
Functional Annotation
- Refseq: XP_010244323.1 — PREDICTED: G-box-binding factor 1-like isoform X2
- TrEMBL: A0A0C9QT24 — A0A0C9QT24_9SPER; TSA: Wollemia nobilis Ref_Wollemi_Transcript_10978_2763 transcribed RNA sequence
- GO:0006355 — Biological Process — regulation of transcription, DNA-templated
- GO:0003700 — Molecular Function — transcription factor activity, sequence-specific DNA binding
- GO:0043565 — Molecular Function — sequence-specific DNA binding
Family Introduction
- The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
- Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.
Literature and News
Gene Resources
Homologs
- Citrullus lanatus: Cla014195
- Cucumis sativus: Cucsa.104970.7, Cucsa.104970.4, Cucsa.104970.3, Cucsa.104970.2, Cucsa.104970.1
- Manihot esculenta: Manes.13G136900.1.p
- Prunus persica: Prupe.7G150700.6.p, Prupe.7G150700.5.p, Prupe.7G150700.3.p, Prupe.7G150700.2.p, Prupe.7G150700.1.p
- Ricinus communis: 29646.m001068
- Sesamum indicum: XP_011097214.1
- Vitis vinifera: GSVIVT01009665001, GSVIVT01019009001
- Ziziphus jujuba: XP_015890164.1, XP_015890163.1, XP_015890162.1, XP_015890160.1
Sequences
CDS Sequence:
- >Pgl009389|Picea_glauca|bZIP|gnl|UG|Pgl#S55336995;PUT-175a-Picea_glauca-17409
ATGGGAACTGGGGAAGAAGGAACACCAACTAAGCCTCCTGCTAAACCATCTTCCTCCTCCCAGGAGACACCAACGACACCTGTTTATCCAGATTGGGCGGCTGCTTTCCAGGCATATTATGGTCCAGGTGCTACCCCACCTCCTCCAGCCTTTTTCGCTTCAACAGTGGGATCTGCACCAACGCCGCATCCACACATGTGGGGAGGACAGCCATTGATGCCGCCTTATGGGACTCCACTACCATATCCTGCAATGTATCCACATGGGGGAATCTATGCACATCCTTCCATGCCTCCGGGTGCACTTCCCTATGGTCATTATGGAATGCCATCACCTGGCAATGCTGAAGTTACAACGACTTTAGCTCTTCCAAATGCTGAAGCAGAAGCCAAGTCCTCAGAAGGAAAAGAACGAAATACAATGAAGAGATCAAAAGGAAGTTTAGGAAGCCTTGGAATGATTACTGGCAAAGGAGGAGAAGGTGGGAAGGCAACTTCAGGATCTGCAAATGAGGCCATGTCAAAACCTGGGGACAGTGGCAGTGATGGTTCAAGCGAAGGAAGTGAGGAAGACAACACTCAAAATGAGTCACAAGTCGCAAGAAAGAGAAGTTTTGATCAAATGATAGTAGATGGAGCAAATGCTCAGGGTACCAATATGTCGGCATATAATACTCAGACCGGAGAACCGTATGTGGCTTCCAGCGGGCATGCAATGGGTAATCCCATTAGTCAAGCTGTTGTTCCACTGGGCTCAGTGACAGGAAAGCCAGCAACCAGTGGGCCTATCACTAATTTGAATATTGGTATGGACTACTGGAATGCTGCTGCACCTGGAGCTATAACAACTGTAAAAGGAAGGGGTAGTACAGCTGGTATTCCGACGGCAATAGTTCCAACAACTGCCCAACTTATGCCACCTGGCCGTGATGGCGTCCCTCCTGAGCTATGGATCCAGGATGAAAGGGAACTGAAGCGACAGAGGCGAAAGCAATCTAATCGGGAGTCAGCCAGACGTTCAAGGTTGCGGAAACAGGCTGAGTGTGAAGAACTGGCAACAAAAGTTGATACCTTGACTGTAGAAAACATGGCACTTAGAAGTGAACTTAACCGAATGGCAGAGGAATGCAAAAAGCTAACTGCAGAGAATGCTTCCATAATGGAACGACTGAAGAAGTTGCATGGAGAAGATATGACGACTATTACTGAAGAAAATGGTTCCACTAAGATATCATTGCAGTCGGTAAAACCTGAAGGCAATGGACATTTTCATGATATATCTAGGGGAATCAATTCAAATTCCACTGAAAGAAATGAACAAAGGCAAAGTGAGACCTGTGATTCAAATGGGAAGGTTCATACATTACTAGATGCAAATGCTCGTTCTGACACAGGTTGA
Protein Sequence:
- >Pgl009389|Picea_glauca|bZIP|gnl|UG|Pgl#S55336995;PUT-175a-Picea_glauca-17409
MGTGEEGTPTKPPAKPSSSSQETPTTPVYPDWAAAFQAYYGPGATPPPPAFFASTVGSAPTPHPHMWGGQPLMPPYGTPLPYPAMYPHGGIYAHPSMPPGALPYGHYGMPSPGNAEVTTTLALPNAEAEAKSSEGKERNTMKRSKGSLGSLGMITGKGGEGGKATSGSANEAMSKPGDSGSDGSSEGSEEDNTQNESQVARKRSFDQMIVDGANAQGTNMSAYNTQTGEPYVASSGHAMGNPISQAVVPLGSVTGKPATSGPITNLNIGMDYWNAAAPGAITTVKGRGSTAGIPTAIVPTTAQLMPPGRDGVPPELWIQDERELKRQRRKQSNRESARRSRLRKQAECEELATKVDTLTVENMALRSELNRMAEECKKLTAENASIMERLKKLHGEDMTTITEENGSTKISLQSVKPEGNGHFHDISRGINSNSTERNEQRQSETCDSNGKVHTLLDANARSDTG