Gene Details:
- Gene ID: Ote100209760021
- Gene Family: bZIP Family
- Description: bZIP Family protein
- Species: Ocimum tenuiflorum
- Source: bZIP family gene from PlantTFDB
Protein Features:
- SMART: SM00338
- Gene3D: G3DSA:1.20.5.170
- PROSITE profile: PS50217
- Pfam: PF00170
- SuperFamily: SSF57959
- PROSITE pattern: PS00036
- InterPro: IPR004827
Annotation Proteins:
- Refseq: XP_011082307.1 — bZIP transcription factor 16-like isoform X1
- Refseq: XP_011082308.1 — bZIP transcription factor 16-like isoform X1
- Refseq: XP_011082309.1 — bZIP transcription factor 16-like isoform X1
- Refseq: XP_011082310.1 — bZIP transcription factor 16-like isoform X2
- Refseq: XP_020550561.1 — bZIP transcription factor 16-like isoform X2
- Refseq: XP_020550562.1 — bZIP transcription factor 16-like isoform X2
- Swissprot: Q501B2 — BZP16_ARATH; bZIP transcription factor 16
- TrEMBL: A0A4D8Y7P4 — A0A4D8Y7P4_SALSN; Plant G-box-binding factor
- STRING: XP_008238155.1 — (Prunus mume)
Family Introduction:
- The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
- Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.
Literature:
Sequences:
CDS Sequence:
- >Ote100209760021|Ocimum_tenuiflorum|bZIP|Ote100209760021
Protein Sequence:
- >Ote100209760021|Ocimum_tenuiflorum|bZIP|Ote100209760021
MTKRESVDVVSTVDLRVDDWIQIVDYLTTSSAPGAVLADWSGFHVNVLKNIPWLIDEKSSEGKGKLPIKISKESLGSLNMIIGKNDEPDKTSGAKPNGVHPKRGESASEGSGEGTDAIEPPQSAPNSSQNEAHGTSHTMVNPAMAMVPIPASVVWAVSGVPGPTTNLNIRVDYWGTAAPSPGMPAMQGKVPATEVAGEIVATGSRDNIQSQLWTQAECDDLAQRAESLKEENASLRAEMARIKSEYDQLVA