Gene Details:

  • Gene ID: orange1.1g015262m
  • Gene Name: CISIN_1g015258mg, LOC102614544
  • Gene Family: bZIP Family
  • Description: bZIP Family protein
  • Species: Citrus sinensis
  • Source: bZIP family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  XP_006421096.1  — transcription factor HBP-1b(c38)
  • Refseq:  XP_006421097.1  — transcription factor HBP-1b(c38)
  • Refseq:  XP_006477494.1  — transcription factor HBP-1b(c38)
  • Refseq:  XP_024954454.1  — transcription factor HBP-1b(c38)
  • Swissprot:  O24160  — TGA21_TOBAC; TGACG-sequence-specific DNA-binding protein TGA-2.1
  • TrEMBL:  A0A067E0Z9  — A0A067E0Z9_CITSI; Uncharacterized protein
  • TrEMBL:  V4S682  — V4S682_9ROSI; Uncharacterized protein
  • STRING:  XP_006477494.1  — (Citrus sinensis)
  • STRING:  XP_006421095.1  — (Citrus clementina)

Gene Ontology:

  • GO:0006355  — Biological Process — regulation of transcription, DNA-templated
  • GO:0003700  — Molecular Function — transcription factor activity, sequence-specific DNA binding
  • GO:0043565  — Molecular Function — sequence-specific DNA binding

Family Introduction:

  • The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
  • Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Literature:

Sequences:

CDS Sequence:
  • >orange1.1g015262m|Citrus_sinensis|bZIP|orange1.1g015262m
    ATGGAGAATGCTGTTGACCTTAGCAGAAATAGTGTATTTTATCAAATGAAGACAGGTAACCAGGCAGTAGGAACTGATGTCCAATTTGGCACCTTGAGTAAGACACTTGCCTCCTCAGATATAAACCTTTCGTCACATATTGTGGGGTCCCAGTCAATGCCACTACAAAAAGAACCTCAATCGAATTTGATTTCTGTATCTAGTGGTCATCGAGAGAACTGGGGGGAGTCCAACATGGCAGAAGCCAGTCCAATAACTGATACGTCAACAGATGATACAGAAGATAAAAATCAAAGGTTTGAAAGAGGTCAATTGACAGCTGTTGCAGCTTCTGATTCTAGTGACAAATCAAAAGAAAAATCAGGGGATCAGAAGACGTTACGCCGGCTTGCTCAGAATCGTGAGGCTGCCAGGAAAAGCCGGTTACGGAAAAAGGCATATGTCCAACAACTGGAGAGCAGTCGGCTTAAACTTACTCAACTAGAGCAAGAGCTCCAGCGTGCTCGCCAGCAGGGTATATTCATTTCCAGTTCAGGAGATCAATCCCATTCAATGAGCGGCAATGGTGCAGCAGCATTTGATGTAGAATATTCTCGCTGGCTTGAAGAGCACAACAGGCATATAGTTGAGCTAAGGGCTGCAGTCAATTCACATGCAGGGGACACTGAACTCCGTACTATCGTTGACAACGTTACATCACACTTTGATGAAATTTTCAGGCTTAAAGGCATTGCTTCAAAGGCTGATGTCTTCCACATCTTGTCAGGAATGTGGAAGACACCAGCAGAAAGGTGTTTTATGTGGATTGGTGGGTTTCGGTCATCTGAGCTCCTTAAGCTTCTTGTGAATCAGTTGGAGCCTTTAACCGAGCAGCAGTTGGTAGGCATCTATAATTTGCAGCAGTCATCCCAACAGGCAGAAGATGCTCTGTCACAAGGGATGGATGCATTGCAGCAATCTCTGGCTGAGACATTGGCCAATGGGTCACCCAGCCCATCGGGAACATCTGGGAATGTTGCAAACTACATGGGTCAAATGGCCATGGCAATGGGAAAGCTAGGAACTCTTGAAGGGTTTCTTCGGCAGGCTGATAATCTACGTCAGCAAACTCTACAACAGATGCATCGTATATTGACCACCCGACAATCAGCTCGTGCGTTGCTCGCAATAAATGATTACTTCTCTAGGCTTAGAGCCCTCAGTTCTCTCTGGCTGGCCCGGCCACGGGAGTGA
Protein Sequence:
  • >orange1.1g015262m|Citrus_sinensis|bZIP|orange1.1g015262m
    MENAVDLSRNSVFYQMKTGNQAVGTDVQFGTLSKTLASSDINLSSHIVGSQSMPLQKEPQSNLISVSSGHRENWGESNMAEASPITDTSTDDTEDKNQRFERGQLTAVAASDSSDKSKEKSGDQKTLRRLAQNREAARKSRLRKKAYVQQLESSRLKLTQLEQELQRARQQGIFISSSGDQSHSMSGNGAAAFDVEYSRWLEEHNRHIVELRAAVNSHAGDTELRTIVDNVTSHFDEIFRLKGIASKADVFHILSGMWKTPAERCFMWIGGFRSSELLKLLVNQLEPLTEQQLVGIYNLQQSSQQAEDALSQGMDALQQSLAETLANGSPSPSGTSGNVANYMGQMAMAMGKLGTLEGFLRQADNLRQQTLQQMHRILTTRQSARALLAINDYFSRLRALSSLWLARPRE*