Gene Details:
- Gene ID: LOC_Os02g08540.1
- Gene Name: LOC4328519, OJ1297_C09.35, Os02g0182700, OSNPB_020182700
- Gene Family: bZIP Family
- Description: bZIP Family protein
- Species: Oryza sativa subsp. japonica
- Source: bZIP family gene from PlantTFDB
Protein Features:
- SMART: SM00338
- Gene3D: G3DSA:1.20.5.170
- PROSITE profile: PS50217
- Pfam: PF00170
- SuperFamily: SSF57959
- PROSITE pattern: PS00036
- InterPro: IPR004827
Annotation Proteins:
- Refseq: XP_015626239.1 — uncharacterized protein LOC4328519 isoform X1
- TrEMBL: Q6H7Z8 — Q6H7Z8_ORYSJ; Os02g0182700 protein
- STRING: OS02T0182700-01 — (Oryza sativa)
Family Introduction:
- The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
- Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.
Literature:
Sequences:
CDS Sequence:
- >LOC_Os02g08540.1|Oryza_sativa_subsp._japonica|bZIP|LOC_Os02g08540.1
ATGGATTGTGCGGGGGACGACGACGCGGTGGCGGCGGGCATCATCTGCTCGCTGCGGGGGGCGGACCTGGCGGGGTGGACGCCGCCGTGGTGGTGCAGCAGCAGCAGCAAGGGGGCGGCGCGGGAGGAGCTGATCTGGCCGCCGGTGACGCGGGGGAAGCGGTCGCGCCGCCGGTCTCCGTCGGCGGTGGCGGCGGCGGCGGGGAAGAAGGGGAGGTGGGCCCGGGCTAGCCCGGCCTCGCCGCTGGACTACAGCGGCGGCTCCGGCTCCGGGTCTGGCTCTGGCTCCGGGTCGGCCGCGTCCACCAGCGGCGGCGAGGACGGCGCCTTCTGCTCGCCTCCCGGACACCGCCCCGCGCCGGCGACGACCAAGGTTAGCGCCATGGGTCGGCAGCAACAACTGCCATTCTCAGCGCCGTCGCCTCTACGGCCGGCCGGTCAGCGTCCACGGAAGAAAATGAGGCTACCGGACGTACAGCAGCTGGTGCGATCTCTTGCAGTGGAGAACGACAGCCTCCGTGAGGAGATGCGTACTTTGCAGAGAGCTTGCGCTGCGCTTTCAAAAGAAAACGACAAGCTTGAGATAAGATTACAGATCTCGAGCTCACGGAACAAACCGATGATTACAGAGGATCTAAAAGGAAAGCAACAGATTGATCAGCAGTCAGCCACGCAGTCCATCGGAGGCGGCTTCGCTCTTCCAGATCTCAACATTCCTGTGCAGGACGCTGCTGATGGATCAGTCCATTGA
Protein Sequence:
- >LOC_Os02g08540.1|Oryza_sativa_subsp._japonica|bZIP|LOC_Os02g08540.1
MDCAGDDDAVAAGIICSLRGADLAGWTPPWWCSSSSKGAAREELIWPPVTRGKRSRRRSPSAVAAAAGKKGRWARASPASPLDYSGGSGSGSGSGSGSAASTSGGEDGAFCSPPGHRPAPATTKVSAMGRQQQLPFSAPSPLRPAGQRPRKKMRLPDVQQLVRSLAVENDSLREEMRTLQRACAALSKENDKLEIRLQISSSRNKPMITEDLKGKQQIDQQSATQSIGGGFALPDLNIPVQDAADGSVH*