Gene Details:

  • Gene ID: Lj0g3v0236609.1
  • Gene Family: bZIP Family
  • Description: bZIP Family protein
  • Species: Lotus japonicus
  • Source: bZIP family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  XP_027925351.1  — transcription factor VIP1-like
  • Swissprot:  O22873  — BZP18_ARATH; bZIP transcription factor 18
  • TrEMBL:  A0A4D6M145  — A0A4D6M145_VIGUN; Plant G-box-binding factor
  • STRING:  XP_007152046.1  — (Phaseolus vulgaris)

Gene Ontology:

  • GO:0006355  — Biological Process — regulation of transcription, DNA-templated
  • GO:0007231  — Biological Process — osmosensory signaling pathway
  • GO:0008272  — Biological Process — sulfate transport
  • GO:0009294  — Biological Process — DNA mediated transformation
  • GO:0009652  — Biological Process — thigmotropism
  • GO:0009970  — Biological Process — cellular response to sulfate starvation
  • GO:0045596  — Biological Process — negative regulation of cell differentiation
  • GO:0051170  — Biological Process — nuclear import
  • GO:0005634  — Cellular Component — nucleus
  • GO:0005829  — Cellular Component — cytosol
  • GO:0003682  — Molecular Function — chromatin binding
  • GO:0003700  — Molecular Function — transcription factor activity, sequence-specific DNA binding
  • GO:0043565  — Molecular Function — sequence-specific DNA binding
  • GO:0043621  — Molecular Function — protein self-association
  • GO:0051019  — Molecular Function — mitogen-activated protein kinase binding

Family Introduction:

  • The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
  • Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Literature:

Sequences:

CDS Sequence:
  • >Lj0g3v0236609.1|Lotus_japonicus|bZIP|Lj0g3v0236609.1
    ATGGACGGGTCTTCTACGACGTCGTTTGAGGCTGACTCGTTGATGATGTTGGACGGTGTGAAGAAGTCAATGGCACCTGATAAACTCGCTGAGCTTGCTCTTATTGATCCAAAGAGAGCTAAGAGGATTCTTGCTAATAGACAATCTGCTGCGCGATCAAAGGAGAGGAAAACGCGTTATACAAGTGAGCTGGAGAGGAAGGTGCAAACGCTTCAAACTGAAGCAACTAATCTCTCTGCTCAGCTCACCATGCTTCAGAGAGACACCACAGATTTGACC
Protein Sequence:
  • >Lj0g3v0236609.1|Lotus_japonicus|bZIP|Lj0g3v0236609.1
    MDGSSTTSFEADSLMMLDGVKKSMAPDKLAELALIDPKRAKRILANRQSAARSKERKTRYTSELERKVQTLQTEATNLSAQLTMLQRDTTDLT