Gene Details:

Protein Features:

Gene Ontology:

  • GO:0006355  — Biological Process — regulation of transcription, DNA-templated
  • GO:0007264  — Biological Process — small GTPase mediated signal transduction
  • GO:0009958  — Biological Process — positive gravitropism
  • GO:0010928  — Biological Process — regulation of auxin mediated signaling pathway
  • GO:0005730  — Cellular Component — nucleolus
  • GO:0005737  — Cellular Component — cytoplasm
  • GO:0005819  — Cellular Component — spindle
  • GO:0005886  — Cellular Component — plasma membrane
  • GO:0030427  — Cellular Component — site of polarized growth
  • GO:0003700  — Molecular Function — transcription factor activity, sequence-specific DNA binding
  • GO:0003924  — Molecular Function — GTPase activity
  • GO:0005525  — Molecular Function — GTP binding
  • GO:0043565  — Molecular Function — sequence-specific DNA binding

Family Introduction:

  • The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
  • Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Literature:

Sequences:

CDS Sequence:
  • >Itr_sc000455.1_g00007.1|Ipomoea_trifida|bZIP|Itr_sc000455.1_g00007.1
    ATGAGCGCCTCTCGGTTCATAAAGTGCGTCACCGTCGGCGACGGAGCTGTCGGTAAAACTTGCCTCCTCATCTCCTACACCAGCAACACTTTCCCCACTGATTATGTCCCAACCGTTTTTGACAACTTCAGTGCCAATGTGGTTGTGGATGGGAGTACTGTTAATCTAGGGCTGTGGGATACTGCAGGACAAGAGGATTACAATAGATTGAGACCTTTGAGCTATCGTGGAGCAGATGTCTTTATTCTGGCATTTTCGCTCATTAGCAAGGCCAGCTATGAAAATGTATCCAAAAAGTGGATTCCTGAATTGAGGCATTACGCACCAGGAGTGCCAATTATTCTTGTTGGAACAAAGCTAGATCTCCGAGAGGATAAGCAATTTTTCTTAGATCACCCTGGAGCAATACCCATTACCACGGCTCAGGGTGAGGAGCTGAAAAAGTTGATTGGCGCTGCTGCTTACATTGAATGTAGTGCAAAAACACAGCAGAATGTGAAGGCTGTTTTTGATGCGGCTATTAAAGTGGTTCTTCAGCCACCAAAGCAAAAGAAGAAAAAGAAGAGAAAGGGTCAGAAAGGGTGCAGTATTTTGTCGGTCCATCCGGGTTGTTGTATATTTGCGATATTTCCAGATATGTTTGAAGTAGTAATGTTGCACAACTCATCTGTTTGTCCCCTAAATCTTACCGCTATCCCTATAAACTATTTTAGTGCTCCTGTGGCTTTATGCTGTTACTGTTCAACTATGTTTTATGACAGATGCATAGTCATTCAGTTGAATGTAAAGACCAATAAAATGGAGCTGCGTTATCCATTGCTGACCACTGACCGCGTCCAAGTTTTCTTTCTGTTCCCGAAATCAAATTCTCTTCTCTCGCTGATCGCTGGTCCGCAGGGCGCTATTCCATCTCCAATTCTTTCAATTGGATTTCGTTACTCTAATCTAATGGATGATGGGGAGCTTGAATTTTCTAACCATGAGATGTTATCGAGTCCTCCGTGTATTGGTGAATTTCCGGACAGTAGTTCAATGGGGAGCTTTTGGAACGATATTCTGAGTGATACCCATGCTTGCACTCATACCCACACTTGCAACCCACCTGGCCCTGATAACTCTCATACACACACTTGTTACCATGTGCACACCAAAATAGTACCTGCAACAAGTGAGGATAAGGCACCCAGTGATGATACTGCGGAATCTGCAGACAAGATAGCGAAGAAACGACCTTCAGGCAATCGGGAAGCAGTCCGCAAGTACCGGGAAAAGAAGAAGGCTAGGGCTGCTTCATTAGAGGATGAAGTTGTCAGACTGAGGACTATTAATCAGCAACTGCTGAAGAGACTCCAGGGCCAGGCAGTGCTGGAAGCTGAGATTGCCAGGCTAAAGTGTTTGCTTGTGGATATTAGAGGAAGGATTGAAGGTGAAATTGGATCATTTCCATACCAAAAGCCTGTGAAGAGTGGTGATTTATATCCGAATCTTGCTAACCCTACCTTGCCAGGGGCATATATTATGAACCCCTGCAATATGCACTGTAACGATCAAGTTTATTGCCTCCACCATGGTTCAGAAGGTAAAAGCTCAGAGGGCACAACATTGAACAACCAAGGCACCAGTAATTGTGAATTTGAGAGTCTGCAATGTTTTGGCAATCAGACTTCTGGTCTGAATGAGCTTCCTGGGTGCGGAGTGGGCAGCAATATGTCTACTCGTAATGCCACTGGAAAGACTAAGAAAAAAGAAGGGATACTCAACTTCCTGACCATTATGCTGAATCAGTTTCATATTGACATGACAAAAGATTGGATTGCTGGCTAA
Protein Sequence:
  • >Itr_sc000455.1_g00007.1|Ipomoea_trifida|bZIP|Itr_sc000455.1_g00007.1
    MSASRFIKCVTVGDGAVGKTCLLISYTSNTFPTDYVPTVFDNFSANVVVDGSTVNLGLWDTAGQEDYNRLRPLSYRGADVFILAFSLISKASYENVSKKWIPELRHYAPGVPIILVGTKLDLREDKQFFLDHPGAIPITTAQGEELKKLIGAAAYIECSAKTQQNVKAVFDAAIKVVLQPPKQKKKKKRKGQKGCSILSVHPGCCIFAIFPDMFEVVMLHNSSVCPLNLTAIPINYFSAPVALCCYCSTMFYDRCIVIQLNVKTNKMELRYPLLTTDRVQVFFLFPKSNSLLSLIAGPQGAIPSPILSIGFRYSNLMDDGELEFSNHEMLSSPPCIGEFPDSSSMGSFWNDILSDTHACTHTHTCNPPGPDNSHTHTCYHVHTKIVPATSEDKAPSDDTAESADKIAKKRPSGNREAVRKYREKKKARAASLEDEVVRLRTINQQLLKRLQGQAVLEAEIARLKCLLVDIRGRIEGEIGSFPYQKPVKSGDLYPNLANPTLPGAYIMNPCNMHCNDQVYCLHHGSEGKSSEGTTLNNQGTSNCEFESLQCFGNQTSGLNELPGCGVGSNMSTRNATGKTKKKEGILNFLTIMLNQFHIDMTKDWIAG