Gene Details:

  • Gene ID: GRMZM2G361847_P07
  • Gene Name: gpm517
  • Gene Family: bZIP Family
  • Description: bZIP Family protein
  • Species: Zea mays
  • Source: bZIP family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  NP_001333859.1  — uncharacterized protein LOC100279481
  • Refseq:  XP_008651318.1  — uncharacterized protein LOC100279481 isoform X2
  • Refseq:  XP_008651320.1  — uncharacterized protein LOC100279481 isoform X2
  • Refseq:  XP_020396043.1  — uncharacterized protein LOC100279481 isoform X2
  • Refseq:  XP_020396044.1  — uncharacterized protein LOC100279481 isoform X2
  • Refseq:  XP_020396045.1  — uncharacterized protein LOC100279481 isoform X6
  • Refseq:  XP_020396047.1  — uncharacterized protein LOC100279481 isoform X6
  • Swissprot:  Q7X993  — TGA21_ORYSJ; Transcription factor TGA2.1
  • TrEMBL:  A0A1D6INY9  — A0A1D6INY9_MAIZE; Transcription factor TGA6
  • STRING:  GRMZM2G361847_P01  — (Zea mays)

Gene Ontology:

  • GO:0006355  — Biological Process — regulation of transcription, DNA-templated
  • GO:0003700  — Molecular Function — transcription factor activity, sequence-specific DNA binding
  • GO:0043565  — Molecular Function — sequence-specific DNA binding

Family Introduction:

  • The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
  • Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Literature:

Sequences:

CDS Sequence:
  • >GRMZM2G361847_P07|Zea_mays|bZIP|GRMZM2G361847_P07
    ATGGAGAATGGAAGTGGTGCGGTTGTACCTTCTAATTCTTCAGATAGGTCCGACAGGTCTGATAAACCTTTGGACCAAAAGACAATGCGACGGCTTGCCCAAAATCGTGAGGCAGCAAGAAAAAGTCGGCTGAGGAAAAAGGCATATGTGCAGCAGCTGGAGAGCAGTAAGCTGAAACTTGCACAACTGGAACAGGAACTCCAGAAAGCTCGCCAGCAGGGAATCTTCATTTCTAGCTCTGGAGACCAAACCCATGCCATGAGTGGAAATGGAGCTTTGACTTTTGACATAGAATATGCTAGATGGCTAGAGGACCAAAATAAGCAGATAAATGAGTTGAGGACTGCAGTGAATGCTCATGCAAGTGATAGTGATCTACGACTTATTGTAGATGGCATAATGGCACACTATGATGAAATATTCAAGGTCAAAGGTGTTGCTGCAAAGGCTGATGTGTTTCATATACTTTCAGGCATGTGGAAGACACCTGCTGAAAGGTGCTTCCTATGGCTTGGGGGTTTTCGTCCATCTGAGCTTTTAAAGCAATCTTCCCAACAAGCAGAGGATGCGTTGTCACAGGGCATGGAAGCACTGCAGCAATCTTTGGCAGAGACTTTGGCTGGATCTCTCGGTCCAGCAGGTTCTTCAGGAAATGTGGCAAACTACATGGGTCAGATGGCCATGGCCATGGGCAAACTCGGGACGCTAGAGAATTTTCTT
Protein Sequence:
  • >GRMZM2G361847_P07|Zea_mays|bZIP|GRMZM2G361847_P07
    MENGSGAVVPSNSSDRSDRSDKPLDQKTMRRLAQNREAARKSRLRKKAYVQQLESSKLKLAQLEQELQKARQQGIFISSSGDQTHAMSGNGALTFDIEYARWLEDQNKQINELRTAVNAHASDSDLRLIVDGIMAHYDEIFKVKGVAAKADVFHILSGMWKTPAERCFLWLGGFRPSELLKQSSQQAEDALSQGMEALQQSLAETLAGSLGPAGSSGNVANYMGQMAMAMGKLGTLENFL