Gene Details:

  • Gene ID: GRMZM2G131961_P04
  • Gene Name: LOC100502433
  • Gene Family: bZIP Family
  • Description: bZIP Family protein
  • Species: Zea mays
  • Source: bZIP family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  XP_023157326.1  — putative bZIP transcription factor superfamily protein isoform X2
  • Swissprot:  A0A0P0WFC8  — TGAL6_ORYSJ; Transcription factor TGAL6
  • TrEMBL:  A0A1D6DX22  — A0A1D6DX22_MAIZE; Transcription factor TGA4
  • TrEMBL:  C0PF87  — C0PF87_MAIZE; Uncharacterized protein
  • TrEMBL:  C0PM36  — C0PM36_MAIZE; BZIP transcription factor
  • TrEMBL:  C4JBE8  — C4JBE8_MAIZE; Uncharacterized protein
  • STRING:  GRMZM2G131961_P01  — (Zea mays)

Gene Ontology:

  • GO:0006355  — Biological Process — regulation of transcription, DNA-templated
  • GO:0042742  — Biological Process — defense response to bacterium
  • GO:0003700  — Molecular Function — transcription factor activity, sequence-specific DNA binding
  • GO:0043565  — Molecular Function — sequence-specific DNA binding
  • GO:0044212  — Molecular Function — transcription regulatory region DNA binding

Family Introduction:

  • The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
  • Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Literature:

Sequences:

CDS Sequence:
  • >GRMZM2G131961_P04|Zea_mays|bZIP|GRMZM2G131961_P04
    ATGAGAAGGCTCGCGCAGAACAGGGAGGCTGCTCGGAAGAGTCGCCTGCGGAAAAAGGCCTACATCCAGCAGCTAGAGACAAGCCGGATGAAGCTGGCCCAGCTAGAGCTGGAGCTTCAACGGGCTCGACGGCAGCAGGGCGCGTACGCAAATGGGAGCATGGGAGACCCAGCTCTCGGATACACAGGGTCGATCGATCCAGGCGTCGCCGCGTTCGAGATCGAATACAGGCACTGGGTGGACGAGCAGAAGCGGCACACGGCGGAGCTGATGTCGGCGCTCCAGGGGCAGCAGACGTCGGAGCTGGAGCTCCGCTTGCTGGTGGAGACGGGGCTCAGCAACTACGAGCACCTCTTCAGGATCAAGGCGCTGGCCGCCAACGCGGACGTGTTCCACGTCATGTCGGGCGTGTGGAAGACCCCCGCCGAGAGGTTCTTCCTCTGGATCGGCGGGTTCAGGCCGTCGGAGGTCCTAAAGATTCTGAGCCCGCAGCTGGAGCCGCTGGCGGAGGCGCAGCGCATGCTCGTGGGCGGCCTCCAGCACACGTCAACGCAGGCGGAGGACGCGCTGTCGCAGGGCATGGAGAAGCTACAGCAGAACCTCGCCGAGATCCTGACCGCCGAGGCTGACCCCTTCGGGGCCCCCGACGCCTACATGCTGCAGATGGCCACTGCGGTGGAGAAGCTGAAAGAGCTCGTCAACTTCGTCACCCAGGCGGACCATCTCCGGCTGATGACGCTGCAACAGATGCACAAGATCCTGACGACGCGGCAGGCGGCCAGGGGCCTGCTGGCGCTCGGCGACTACTTCCAGCGCCTCCGCACGCTGAGCTCGCTGTGGGCGGCGCGCCCGCGGGAGGCGGCGATTAGCTAG
Protein Sequence:
  • >GRMZM2G131961_P04|Zea_mays|bZIP|GRMZM2G131961_P04
    MRRLAQNREAARKSRLRKKAYIQQLETSRMKLAQLELELQRARRQQGAYANGSMGDPALGYTGSIDPGVAAFEIEYRHWVDEQKRHTAELMSALQGQQTSELELRLLVETGLSNYEHLFRIKALAANADVFHVMSGVWKTPAERFFLWIGGFRPSEVLKILSPQLEPLAEAQRMLVGGLQHTSTQAEDALSQGMEKLQQNLAEILTAEADPFGAPDAYMLQMATAVEKLKELVNFVTQADHLRLMTLQQMHKILTTRQAARGLLALGDYFQRLRTLSSLWAARPREAAIS