Gene Details:

  • Gene ID: Gh_D05G2870
  • Gene Family: bZIP Family
  • Description: bZIP Family protein
  • Species: Gossypium hirsutum
  • Source: bZIP family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  XP_016684569.1  — PREDICTED: ankyrin repeat domain-containing protein 6-like
  • TrEMBL:  A0A1U8J8P0  — A0A1U8J8P0_GOSHI; ankyrin repeat domain-containing protein 6-like
  • STRING:  Gorai.009G317200.1  — (Gossypium raimondii)

Gene Ontology:

  • GO:0005515  — Molecular Function — protein binding

Family Introduction:

  • The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
  • Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Literature:

Sequences:

CDS Sequence:
  • >Gh_D05G2870|Gossypium_hirsutum|bZIP|Gh_D05G2870
    ATGGATGAAAGGTTAAAGAGAGCAGCTGAAACAGGAAACATCGATGCCTTGTATTCTTTCATCCACCACGATGCCAGTGTTTTCAAGCGTATAGATGAGATGGAGTTCGTGGATACGCCATTACACGTTGCCGCAGTTGAGGGCAATACCGGTTTTGCAATGGAGATGATGAACTTGAAGCCATCGTTTGCCAGGAAACTGAACCAGGATGGGTTTTCCCCCCTTCATCTAGCCTTGCTTACTGGAAAACCAGAAATGGTGATTGATTTTTTATCGGTTGATAAAGATCTTATTCGTGTTAAAGGAAAGGGGGGTTTCACTGTTCTTCATCATGTTGCTTTGGATGAAAATTATGCTCATCTCTTGCGTCGGTTTTTGAATTTTTGTCCCGATTGTATCTTTGATTTGACAGTTGAGAGACAAACTGCTTTGCATATAGCTGCAGTGAAAAACAAATTTGAAGCATTTAAAGCGATGTTGGAATGGATTCAAAGTGCGTTTGAAGACGATAAGTGTAAGAGAAGTAAAATATTGAACTATCAGGATAAGGATGGCAACACTGTACTGCACTTAGCTGCATCAATTAACCACCCCCAGATGATCAAACTGTTGATAGAATGTGAAGAAGTGGACAAGAACAAGATCAATGACCATGGTTTTACAGCAATGGATGTGTTACAAAGTCAAACTGTAGCAGACAACATGGAGAGTGTAAACATCTTAAGCAGTAATCCCCTCACGTTTCAAAAGTTGTCAAGTGTCAAAATATTTCAAGAAGCGATAAAAGAGATGAGAGACGAAACGGTGGGTGTATTACTCATCGTATTCGCGCTGGTTCTAACAATGACATACCAAGGAGTTCTCAGCCCTCCGGGCAGCGTTTTCCAGGGCGATACAACCGCATCAACCAGTTCAAATCATCGTGAAGGGAAATCAGTGATGAAGACGAGTAGTTTTCTTATTTTCTATATTCCAAATGGATTGGCTTTTATTATATCTTGGGGCATAACGTTATTTTTGTTGGAGTCCGTGGCTAAAAGTATCATGTCTTGTTTGTCGCGAATTTACACAATTGTTTTTATCCCCAACTCATCTCCGAAATCCCTTATTTTTTCCCCTAAAAATTTTCCCCGGATCCCTAATTCCCCAAATCAAAATCCCCAAATCTTTCCCCGACCATCTGCTGCATCACAGTTGATTGTCCCCTCTGTCGAATCACCATCGACACTCCTCTGTAGCATCGTCGTTGACACTCCTCTAGTGCATCACCATGGCTCGTACTCTCTGAAAATGAAGATGTTCGATGCAGAAAACATACAAAGACGTCTTGCACAAAATCGTGTGGTTGCTCGTAAAAGCCGTTTGCGGAAAAAGGCATATGTTCAATAG
Protein Sequence:
  • >Gh_D05G2870|Gossypium_hirsutum|bZIP|Gh_D05G2870
    MDERLKRAAETGNIDALYSFIHHDASVFKRIDEMEFVDTPLHVAAVEGNTGFAMEMMNLKPSFARKLNQDGFSPLHLALLTGKPEMVIDFLSVDKDLIRVKGKGGFTVLHHVALDENYAHLLRRFLNFCPDCIFDLTVERQTALHIAAVKNKFEAFKAMLEWIQSAFEDDKCKRSKILNYQDKDGNTVLHLAASINHPQMIKLLIECEEVDKNKINDHGFTAMDVLQSQTVADNMESVNILSSNPLTFQKLSSVKIFQEAIKEMRDETVGVLLIVFALVLTMTYQGVLSPPGSVFQGDTTASTSSNHREGKSVMKTSSFLIFYIPNGLAFIISWGITLFLLESVAKSIMSCLSRIYTIVFIPNSSPKSLIFSPKNFPRIPNSPNQNPQIFPRPSAASQLIVPSVESPSTLLCSIVVDTPLVHHHGSYSLKMKMFDAENIQRRLAQNRVVARKSRLRKKAYVQ