Gene Details:

  • Gene ID: cra_locus_123461_iso_1
  • Gene Family: bZIP Family
  • Description: bZIP Family protein
  • Species: Catharanthus roseus
  • Source: bZIP family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  XP_016556593.1  — PREDICTED: protein ABSCISIC ACID-INSENSITIVE 5
  • Refseq:  XP_016556594.1  — PREDICTED: protein ABSCISIC ACID-INSENSITIVE 5-like
  • Swissprot:  Q9SJN0  — ABI5_ARATH; Protein ABSCISIC ACID-INSENSITIVE 5
  • TrEMBL:  A0A1U8FB82  — A0A1U8FB82_CAPAN; protein ABSCISIC ACID-INSENSITIVE 5
  • TrEMBL:  A0A1U8FJV9  — A0A1U8FJV9_CAPAN; protein ABSCISIC ACID-INSENSITIVE 5-like
  • TrEMBL:  A0A411P8V9  — A0A411P8V9_SOLRO; Abscisic acid-insensitive 5 (Fragment)
  • STRING:  Solyc09g009490.2.1  — (Solanum lycopersicum)

Family Introduction:

  • The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
  • Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Literature:

Sequences:

CDS Sequence:
  • >cra_locus_123461_iso_1|Catharanthus_roseus|bZIP|cra_locus_123461_iso_1
Protein Sequence:
  • >cra_locus_123461_iso_1|Catharanthus_roseus|bZIP|cra_locus_123461_iso_1
    RARKQAYTVELEAELNQLKEENAHLKQVLAELERKRRQQCEEAKMRAQTRAEKANEKLRIMRRSNSCPY