Information report for Carubv10016005m
Gene Details
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Functional Annotation
- Refseq: XP_006296784.1 — bZIP transcription factor 28
- Swissprot: Q9SG86 — BZP28_ARATH; bZIP transcription factor 28
- TrEMBL: R0G2L9 — R0G2L9_9BRAS; Uncharacterized protein
- STRING: XP_006296784.1 — (Capsella rubella)
- GO:0006990 — Biological Process — positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
- GO:0009408 — Biological Process — response to heat
- GO:0005635 — Cellular Component — nuclear envelope
- GO:0005654 — Cellular Component — nucleoplasm
- GO:0005783 — Cellular Component — endoplasmic reticulum
- GO:0016021 — Cellular Component — integral component of membrane
- GO:0048471 — Cellular Component — perinuclear region of cytoplasm
- GO:0003700 — Molecular Function — transcription factor activity, sequence-specific DNA binding
- GO:0043565 — Molecular Function — sequence-specific DNA binding
Family Introduction
- The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
- Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.
Literature and News
Gene Resources
Sequences
CDS Sequence:
- >Carubv10016005m|Capsella_rubella|bZIP|Carubv10016005m
ATGGTGACGACGCAATCAACATCTGTGATCGTTCCTCCGCCGGAAACACCTAATCTGAACCCTAGCATGTTATCGGATTCCGACATCATTTCGTTTCCGCCGCTAGATCCTCTTTTCCTATCTGATTCTGATCCGATTTCAATGGATGCTCCTCTCTCTGACCTCGACTTCTTACTCGACGATGAGAACGGTGATTTTGCCGATTTCGATTTCCCGTTTGATAGTTCGGATGATTTCTTCGATTTCGATTTGGCGGAGCCCGCGGCGGCGGTGATACCTGAGGAGATGGGAAATAATCGTTCCAATTTGGACTCATCGGAAAACAGAGACGGCGATGGAGGCGCAGAAGGACGATCTGATTCTGTTCATTCTCAGGTTTCATCTCAAGGCTCCAAGACGACTTTTGTGTCCGACACCGTTGACGCGTTATCCTCCCCTGAATCGAGCAATCACAAGAAGTCTTCTGTCAGCAAGAGGAAGAAGGAAAAAGAAGACTCCGGCCTTGAACACAGGAGCCGCAAGTATCAAAAGTCCGATGATAAATCAGTCGCTACAAACAACGAAGAGGATGATGACGACAAGAAGAGGTTAAGGCAGATCAGGAACCGTGAAAGTGCTCAGCTTTCGAGGTTGAGGAAGAAGCAACAAACTGAGGAGCTTGAAAGGAAAGTGAAGAGTATGAATGCTACCATTGCTGAACTGAACGGTAAGATTGCTTATGTTATGGCTGAGAATGTAGCTTTAAGGCAACAAATGGCTGTAGCTTCTGGTGCTCCTCCTATGAATCCTTATATGGCTGCACCGCCATTACCTTATCAATGGATGCCATATCCACCGTATCCTGTCAGGGGTTATGGATCACAGACTCCGCTGGTTCCCATTCCTAAGTTAACCCCTAAGCCTGTCTCTAGTTGTAGATCGAAAAAGACAGAGAGTAAGAAGAATGAGGGCAAAAGTAAGCTCAAGAAGGTTGCTAGTATTAGTTTTATTGGAATTCTCTTCTTTGTTTTCTTGTTTGGTACATTAGTTCCGTTTATGAATGTAAATTATGGAGGAGAAAGTGGAAGCTTTGGCGGTTTGTCTAAATATGATGGTCACCGGTACTACCATGAGCACAAGGGGAAGGTTCTAATGGTCGGTGATGGTTCTGATGTTAGAAGAGAAAGTGGAATATCTGACGGACATTTACATTCTAGTAGGAGGGTTCATGGTGATAGCGATAGTTGTGGAGGAGTAGATTATAACCCTCATCCGAAAATAGAGGGACGACCAAGTTCAGTGAGCAATGCTAGTGACCCTCTTTTTGCTTCTCTCTATGTCCCAAGAAACAATGGGCTTGTGAAGATTGACGGGAACTTGATAATTCACTCTGTTTTGGCGAGTGAGAAAGCAACTGCTTTAGCTAAGAAGAATATCACTGCAACAGTAAAAACCAAAGAACCGGATTTGACCATTCCTGGTGCACTTTCTTCTGCGTTAGCTGTTCCTGAGCTAAGAGGAAATGCAGCAATGCTCCCTCAGTCAATGGCTCTATCTTCTGAAGGGAAAAGGCTTCATCAATGGTTTCATGAAGGTGGCTCAGGGACACTAATGGATTATAGCATGTGTACTGAAGTTTTCCAGTTTGATATTGCTCCTGGTGCTATAGTCCCATCATCAGTCTCCAACATTTCAGCGGAGCAGCTCCAAAATGTCACCACCCACGGCAAGAGAATGAAGAACAGGAGAATTCTCGAGGGACTTCCGGTTTCACGTTTGGCATCTGAGCTCAATATCACCGGAACCCAGCCGAACAAAGAAACTCAAAACAAGACCTTCAATGGAAACACTAAGAACAAACCCAACTCATCATCCTCCATGGTTGTCTCAGTGTTGCTTGATCCAAGAGAGATTGTTGACTCTGAAACCGATAGAGTGGTGCCCCCGAATCCTAAATCACTTTCCCGGATCTTTGTGGTGGTGCTCCTCGACAGTGTCAAGTACGTCACCTACTCATGCGTCCTTCCTCGATCTGGTCTCCATCTCGTAGCCACCTGA
Protein Sequence:
- >Carubv10016005m|Capsella_rubella|bZIP|Carubv10016005m
MVTTQSTSVIVPPPETPNLNPSMLSDSDIISFPPLDPLFLSDSDPISMDAPLSDLDFLLDDENGDFADFDFPFDSSDDFFDFDLAEPAAAVIPEEMGNNRSNLDSSENRDGDGGAEGRSDSVHSQVSSQGSKTTFVSDTVDALSSPESSNHKKSSVSKRKKEKEDSGLEHRSRKYQKSDDKSVATNNEEDDDDKKRLRQIRNRESAQLSRLRKKQQTEELERKVKSMNATIAELNGKIAYVMAENVALRQQMAVASGAPPMNPYMAAPPLPYQWMPYPPYPVRGYGSQTPLVPIPKLTPKPVSSCRSKKTESKKNEGKSKLKKVASISFIGILFFVFLFGTLVPFMNVNYGGESGSFGGLSKYDGHRYYHEHKGKVLMVGDGSDVRRESGISDGHLHSSRRVHGDSDSCGGVDYNPHPKIEGRPSSVSNASDPLFASLYVPRNNGLVKIDGNLIIHSVLASEKATALAKKNITATVKTKEPDLTIPGALSSALAVPELRGNAAMLPQSMALSSEGKRLHQWFHEGGSGTLMDYSMCTEVFQFDIAPGAIVPSSVSNISAEQLQNVTTHGKRMKNRRILEGLPVSRLASELNITGTQPNKETQNKTFNGNTKNKPNSSSSMVVSVLLDPREIVDSETDRVVPPNPKSLSRIFVVVLLDSVKYVTYSCVLPRSGLHLVAT*