Gene Details:

  • Gene ID: Bradi1g30750.1.p
  • Gene Name: BRADI_1g30750, LOC100837633
  • Gene Family: bZIP Family
  • Description: bZIP Family protein
  • Species: Brachypodium distachyon
  • Source: bZIP family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  XP_003560357.1  — trinucleotide repeat-containing gene 18 protein
  • TrEMBL:  I1GVI6  — I1GVI6_BRADI; Uncharacterized protein
  • STRING:  BRADI1G30750.1  — (Brachypodium distachyon)

Family Introduction:

  • The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
  • Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Literature:

Sequences:

CDS Sequence:
  • >Bradi1g30750.1.p|Brachypodium_distachyon|bZIP|Bradi1g30750.1.p
    ATGGCGGAAGTTAACGAGGAGGAGTCCTGCCTCGCGGTGCTGGCGGAGGCGGCGGGCATCATCTGCTCCCTCCGCGCGGGGGACCTCGCCGGGTGGACCCCGCCATGGACGACCGGGCCGACCGCCGAAGCTCTTGTAGGACCGACCAAGGAGGAGATGGGGGCCTGGCCGGCGGTGACAAGGGGGAAGCGGTCGAGGTCGTCGCGTGGCTCGGGATCCGCCGCGGCTAAGGTGGGGAGGAGGAGGGCCCGCGGCAGCCCGGCGTCTCCCCTCGACTACAGCGCCGCGTCCGGCTCCGGCTCCGGCGTTTCCACGAGCGGCGGCGAGGACGGCGCCGTCTTCTGCTCGCCGCCAGCTCCTGCTGCGGCTGCGTCGGCGGCGGCGGTTCCCCAGTCCGTGCCCACCACCGCCGCCACGGCTTCTTCGGCCAAGGTGTGCTCCGCCGGAGTACGGCGCCCGCCGCCCCGGCCAGCCGCCCCCGGACCGCGCTCCCGGAAGAAGATGAGGCTCCCGGAGGTGCAGCAGCTGGTGCGGTCCCTGGCGGCGGAGAACGACGGCCTCCGCGAGGAGGTGGAGTCGCTGCAGAGGGCTTGTTCGGCGCTGTCCAGGGAGAACGGCACGCTAGAGACAAGGTTGGAGCACTCCTCGAGCAAGCGAAAGAGGACCGTTTCCGAAGAGGAGGATCGCCCTCGACAACGGAAGCCGATGCTGCAGCAGCTTGGCCAGCATGCGGCGGAGCACCGGGGCGCCCGGGAGGGCTTCGTGCTGCCCGATCTCAACATTCCAGCGGCGGCACCAGACGACGTCGGATCAGCTCCCTGA
Protein Sequence:
  • >Bradi1g30750.1.p|Brachypodium_distachyon|bZIP|Bradi1g30750.1.p
    MAEVNEEESCLAVLAEAAGIICSLRAGDLAGWTPPWTTGPTAEALVGPTKEEMGAWPAVTRGKRSRSSRGSGSAAAKVGRRRARGSPASPLDYSAASGSGSGVSTSGGEDGAVFCSPPAPAAAASAAAVPQSVPTTAATASSAKVCSAGVRRPPPRPAAPGPRSRKKMRLPEVQQLVRSLAAENDGLREEVESLQRACSALSRENGTLETRLEHSSSKRKRTVSEEEDRPRQRKPMLQQLGQHAAEHRGAREGFVLPDLNIPAAAPDDVGSAP*