Gene Details:
- Gene ID: BGIOSGA017801-PA
- Gene Name: OsI_20459
- Gene Family: bZIP Family
- Description: bZIP Family protein
- Species: Oryza sativa subsp. indica
- Source: bZIP family gene from PlantTFDB
Protein Features:
- SMART: SM00338
- Gene3D: G3DSA:1.20.5.170
- PROSITE profile: PS50217
- Pfam: PF00170
- SuperFamily: SSF57959
- PROSITE pattern: PS00036
- InterPro: IPR004827
Annotation Proteins:
- Refseq: XP_015638714.1 — basic leucine zipper 23
- Refseq: XP_025881179.1 — basic leucine zipper 23
- Refseq: XP_025881180.1 — basic leucine zipper 23
- Refseq: XP_025881181.1 — basic leucine zipper 23
- Refseq: XP_025881182.1 — basic leucine zipper 23
- Swissprot: Q8GTS2 — BZP23_ARATH; Basic leucine zipper 23
- TrEMBL: A0A0D3G9C5 — A0A0D3G9C5_9ORYZ; Uncharacterized protein
- TrEMBL: A0A0E0HGB5 — A0A0E0HGB5_ORYNI; Uncharacterized protein
- TrEMBL: A0A0E0PPE3 — A0A0E0PPE3_ORYRU; Uncharacterized protein
- TrEMBL: A2Y636 — A2Y636_ORYSI; Uncharacterized protein
- TrEMBL: I1PWW4 — I1PWW4_ORYGL; Uncharacterized protein
- TrEMBL: Q65X73 — Q65X73_ORYSJ; Os05g0495200 protein
- STRING: ORUFI05G22690.1 — (Oryza rufipogon)
- STRING: OS05T0495200-01 — (Oryza sativa)
- STRING: ONIVA05G22130.1 — (Oryza nivara)
- STRING: ORGLA05G0186200.1 — (Oryza glaberrima)
- STRING: OBART05G21450.1 — (Oryza barthii)
Gene Ontology:
- GO:0006355 — Biological Process — regulation of transcription, DNA-templated
- GO:0003700 — Molecular Function — transcription factor activity, sequence-specific DNA binding
- GO:0043565 — Molecular Function — sequence-specific DNA binding
Family Introduction:
- The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
- Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.
Literature:
Sequences:
CDS Sequence:
- >BGIOSGA017801-PA|Oryza_sativa_subsp._indica|bZIP|BGIOSGA017801-PA
ATGGACGATGTCCCAAGTCAATTGCTCTTCTCCCATCCGGAGGTGCCTGATAGCTTCGATGATTTCTTGAACAACATCACAACCTGCACCCACACCCACACCTGCAATCCTCCTGGTCCGTCGGCAACCATGCACACCCACACATGCTTGCACACGCACACCCAGGTCTTCGCCTCCGGCAGTGGCGAAGATGACATCAAGGAGGACCTGACGAAGACCCGGAGGCCGCTGGGGAACAGGGAAGCCGTGCGCAAGTATCGGGAGAAGAAGAAGGCGCATGCGGCTTTCTTGGAGGAGGAGGTCAAGAAGCTCCGCGCCGCCAATCAGCAGCTGCTGAAGCGATTGCAGGGCCATGCTGCGCTCGAGGCTGAGGTGATCAGGTTAAGGAGCATCCTACTCGATGTCCGGGGCAAGATTGATATGGAGATCGGCACATTCCCTTACCAGAAGCCGTGCAGTGTTGGCTCTGTGGCATGCACTGATCCAGGTATGTGCTTCAATGGCAATTCTGAGATTGGAGGGGTCTGGGAGGAGTGCTCTAGACCAGTGGGTGCAGATCGCATGATCGACAAAGATGGTAGCATGTCACAGGAAATTGATATCCCAGGACCGGTGCATTCCATTTCCATGGATGTTGTCGGAAGCTTGGTGACTTCTGCTTCTCTATCTTAG
Protein Sequence:
- >BGIOSGA017801-PA|Oryza_sativa_subsp._indica|bZIP|BGIOSGA017801-PA
MDDVPSQLLFSHPEVPDSFDDFLNNITTCTHTHTCNPPGPSATMHTHTCLHTHTQVFASGSGEDDIKEDLTKTRRPLGNREAVRKYREKKKAHAAFLEEEVKKLRAANQQLLKRLQGHAALEAEVIRLRSILLDVRGKIDMEIGTFPYQKPCSVGSVACTDPGMCFNGNSEIGGVWEECSRPVGADRMIDKDGSMSQEIDIPGPVHSISMDVVGSLVTSASLS