Gene Details:
- Gene ID: BGIOSGA004481-PA
- Gene Name: OsI_03786
- Gene Family: bZIP Family
- Description: bZIP Family protein
- Species: Oryza sativa subsp. indica
- Source: bZIP family gene from PlantTFDB
Protein Features:
- SMART: SM00338
- Gene3D: G3DSA:1.20.5.170
- PROSITE profile: PS50217
- Pfam: PF00170
- SuperFamily: SSF57959
- PROSITE pattern: PS00036
- InterPro: IPR004827
Annotation Proteins:
- Refseq: XP_015634100.1 — basic leucine zipper 6 isoform X1
- Swissprot: Q5JMK6 — BZP06_ORYSJ; Basic leucine zipper 6
- TrEMBL: A0A0D9YF45 — A0A0D9YF45_9ORYZ; Uncharacterized protein
- TrEMBL: A0A0E0C7W2 — A0A0E0C7W2_9ORYZ; Uncharacterized protein
- TrEMBL: A0A0E0N2L4 — A0A0E0N2L4_ORYRU; Uncharacterized protein
- TrEMBL: B8A9R7 — B8A9R7_ORYSI; Uncharacterized protein
- STRING: OGLUM01G35480.1 — (Oryza glumipatula)
- STRING: OMERI01G27760.1 — (Oryza meridionalis)
- STRING: ORUFI01G34500.1 — (Oryza rufipogon)
- STRING: OS01T0756200-01 — (Oryza sativa)
Gene Ontology:
- GO:0045893 — Biological Process — positive regulation of transcription, DNA-templated
- GO:0005634 — Cellular Component — nucleus
- GO:0003700 — Molecular Function — transcription factor activity, sequence-specific DNA binding
- GO:0043565 — Molecular Function — sequence-specific DNA binding
Family Introduction:
- The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
- Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.
Literature:
Sequences:
CDS Sequence:
- >BGIOSGA004481-PA|Oryza_sativa_subsp._indica|bZIP|BGIOSGA004481-PA
ATGGCGCAGCTCCCGCCCAAGATCCCGGTGGCGGCGCCGGGGCACCACCAGCACTGGGCCTCGGCCGGGGGCGCCGGCGACGCGGCGTGGGCGGATGAGTTCGCCGAGTTCGCGGCGTCGCGGCGGGGCGCGCACCGCCGGTCGCTGAGCGACTCCGTGGCGTTCGTCGAGGTGGCGCCGGCGGGGTGCGGGGCGGGCGGCGAGTTCGACAGGCTCGACGACGACCAGCTCATGTCTATGTTCCCCGACGAGGGCGGGTCGTCGGCCCCGGGGTCCGACAACGGCGGCAGCGACAGCGACGGCGGCGGCGACAAGCACGCCGCGGCGCAGAGCGACGACGGGCAGCACGCCGCCGGGGAGCCGACGCAGGAGCAGGCGGCGGCCACCTCGCCGACGGAGCTGATCCGGGACCCCAAGAGGGTCAAGAGGATACTGGCTAATCGGCAGTCGGCCCAGAGGTCGCGAGTGAGGAAGCTTCAGTACATCTCCGAGCTCGAGCGCAGCGTCACAACCCTGCAGAACGAGGTATCCGTGCTGTCCCCTCGGGTGGCGTTTCTGGATCAGCAGCGGACGATCCTGACCGTCGGCAACAGCCACCTCAAGCAGCGGATCGCGGCTCTAGCACAGGACAAGATTTTCAAGGATGCTCATCAGGAGGCGTTGAGGAAGGAGATCGAGAGGCTGAGGCAGGTATACCAGCAGCAGAACACCAAGTTGTCCGGTGGTCTGGCCGCTGACCACGCACATGTCCATGGCGGCCCGCCGCCTGTGCGAGCAGAGAAGGAGCTCATGAGCTAG
Protein Sequence:
- >BGIOSGA004481-PA|Oryza_sativa_subsp._indica|bZIP|BGIOSGA004481-PA
MAQLPPKIPVAAPGHHQHWASAGGAGDAAWADEFAEFAASRRGAHRRSLSDSVAFVEVAPAGCGAGGEFDRLDDDQLMSMFPDEGGSSAPGSDNGGSDSDGGGDKHAAAQSDDGQHAAGEPTQEQAAATSPTELIRDPKRVKRILANRQSAQRSRVRKLQYISELERSVTTLQNEVSVLSPRVAFLDQQRTILTVGNSHLKQRIAALAQDKIFKDAHQEALRKEIERLRQVYQQQNTKLSGGLAADHAHVHGGPPPVRAEKELMS