Gene Details:

  • Gene ID: AT4G02640.2
  • Gene Name: ATBZIP10, BZIP10, BZO2H1, T10P11.9
  • Gene Family: bZIP Family
  • Description: bZIP Family protein
  • Species: Arabidopsis thaliana
  • Source: bZIP family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  NP_849290.1  — bZIP transcription factor family protein
  • Swissprot:  O22763  — BZP10_ARATH; Basic leucine zipper 10
  • TrEMBL:  A0A178V4D9  — A0A178V4D9_ARATH; BZO2H1
  • STRING:  AT4G02640.2  — (Arabidopsis thaliana)

Gene Ontology:

  • GO:0002240  — Biological Process — response to molecule of oomycetes origin
  • GO:0009626  — Biological Process — plant-type hypersensitive response
  • GO:0045893  — Biological Process — positive regulation of transcription, DNA-templated
  • GO:2000693  — Biological Process — positive regulation of seed maturation
  • GO:0005634  — Cellular Component — nucleus
  • GO:0005737  — Cellular Component — cytoplasm
  • GO:0003700  — Molecular Function — transcription factor activity, sequence-specific DNA binding
  • GO:0043565  — Molecular Function — sequence-specific DNA binding
  • GO:0045735  — Molecular Function — nutrient reservoir activity
  • GO:0046982  — Molecular Function — protein heterodimerization activity

Family Introduction:

  • The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
  • Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Literature:

Sequences:

CDS Sequence:
  • >AT4G02640.2|Arabidopsis_thaliana|bZIP|AT4G02640.2
    ATGAACAGTATCTTCTCCATTGACGATTTCTCCGATCCTTTCTGGGAAACTCCTCCGATTCCTCTCAATCCCGACTCTTCTAAGCCTGTTACGGCGGATGAAGTTAGCCAGAGTCAACCGGAATGGACTTTCGAGATGTTTCTCGAAGAGATTTCTTCGTCGGCGGTGAGCTCTGAGCCACTTGGTAACAACAACAACGCGATCGTCGGTGTTTCTTCGGCGCAATCTCTTCCTTCTGTTTCCGGACAGAATGATTTCGAGGATGATAGTCGATTTCGTGATCGCGATTCGGGAAATTTGGATTGTGCTGCTCCCATGACGACGAAGACGGTGATTGTTGATTCCGATGATTATCGTCGTGTTCTTAAGAACAAGCTTGAGACTGAGTGCGCTACTGTTGTTTCTCTTCGGGTTGGGTCTGTGAAGCCTGAAGATTCGACTAGTTCTCCAGAAACTCAACTTCAACCAGTTCAATCCAGTCCTCTTACTCAAGGTTCTTTGATGACCCCAGGAGAACTTGGTGTTACTTCTTCCTTACCAGCTGAGGTGAAAAAAACTGGTGTATCAATGAAGCAGGTTACTAGTGGATCGTCGAGAGAATATTCTGATGACGAGGACCTTGATGAAGAGAATGAAACCACCGGTTCCTTGAAGCCAGAGGACGTTAAAAAATCTAGAAGGATGCTGTCAAATCGTGAGTCAGCTAGGCGATCTAGAAGGAGAAAGCAGGAGCAAACAAGTGACCTCGAAACACAGGTTAATGATCTAAAAGGTGAGCATTCATCACTTCTTAAACAACTGAGCAACATGAATCACAAGTATGACGAGGCTGCTGTTGGCAATAGAATACTAAAGGCTGACATTGAGACATTAAGAGCTAAGGTGAAAATGGCGGAAGAAACCGTGAAGAGAGTAACAGGAATGAATCCGATGCTTCTCGGAAGATCAAGTGGACATAACAACAACAACAGAATGCCAATAACTGGTAACAACAGGATGGATTCTTCTAGCATTATTCCAGCTTATCAACCACACTCAAACCTAAACCATATGTCAAACCAAAACATCGGGATCCCAACCATTCTACCTCCAAGACTCGGAAACAATTTCGCTGCTCCTCCATCCCAAACCAGCTCTCCCTTGCAGAGAATTAGAAATGGGCAAAATCACCATGTTACTCCAAGCGCCAACCCGTATGGCTGGAATACCGAACCTCAGAACGATTCAGCATGGCCGAAAAAATGCGTGGACTGA
Protein Sequence:
  • >AT4G02640.2|Arabidopsis_thaliana|bZIP|AT4G02640.2
    MNSIFSIDDFSDPFWETPPIPLNPDSSKPVTADEVSQSQPEWTFEMFLEEISSSAVSSEPLGNNNNAIVGVSSAQSLPSVSGQNDFEDDSRFRDRDSGNLDCAAPMTTKTVIVDSDDYRRVLKNKLETECATVVSLRVGSVKPEDSTSSPETQLQPVQSSPLTQGSLMTPGELGVTSSLPAEVKKTGVSMKQVTSGSSREYSDDEDLDEENETTGSLKPEDVKKSRRMLSNRESARRSRRRKQEQTSDLETQVNDLKGEHSSLLKQLSNMNHKYDEAAVGNRILKADIETLRAKVKMAEETVKRVTGMNPMLLGRSSGHNNNNRMPITGNNRMDSSSIIPAYQPHSNLNHMSNQNIGIPTILPPRLGNNFAAPPSQTSSPLQRIRNGQNHHVTPSANPYGWNTEPQNDSAWPKKCVD