Gene Details:

  • Gene ID: AT1G45249.2
  • Gene Name: ABF2, AREB1, AtABF2, ATAREB1
  • Gene Family: bZIP Family
  • Description: bZIP Family protein
  • Species: Arabidopsis thaliana
  • Source: bZIP family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  NP_001319166.1  — abscisic acid responsive elements-binding factor 2
  • Refseq:  NP_001322812.1  — abscisic acid responsive elements-binding factor 2
  • Refseq:  NP_001322813.1  — abscisic acid responsive elements-binding factor 2
  • Refseq:  NP_973981.2  — abscisic acid responsive elements-binding factor 2
  • Swissprot:  Q9M7Q4  — AI5L5_ARATH; ABSCISIC ACID-INSENSITIVE 5-like protein 5
  • TrEMBL:  F4HRD0  — F4HRD0_ARATH; Abscisic acid responsive elements-binding factor 2
  • STRING:  AT1G45249.3  — (Arabidopsis thaliana)

Gene Ontology:

  • GO:0009414  — Biological Process — response to water deprivation
  • GO:0009651  — Biological Process — response to salt stress
  • GO:0009738  — Biological Process — abscisic acid-activated signaling pathway
  • GO:0010255  — Biological Process — glucose mediated signaling pathway
  • GO:0045893  — Biological Process — positive regulation of transcription, DNA-templated
  • GO:0005634  — Cellular Component — nucleus
  • GO:0000976  — Molecular Function — transcription regulatory region sequence-specific DNA binding
  • GO:0003700  — Molecular Function — transcription factor activity, sequence-specific DNA binding
  • GO:0005515  — Molecular Function — protein binding

Family Introduction:

  • The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
  • Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Literature:

Sequences:

CDS Sequence:
  • >AT1G45249.2|Arabidopsis_thaliana|bZIP|AT1G45249.2
    ATGGATGGTAGTATGAATTTGGGGAATGAGCCACCAGGAGATGGTGGTGGAGGTGGAGGGTTGACTAGACAAGGTTCGATATACTCGTTGACGTTTGATGAGTTTCAGAGCAGTGTAGGGAAAGATTTTGGGTCAATGAACATGGATGAGTTGTTAAAGAATATATGGAGTGCTGAAGAAACACAAGCCATGGCTAGTGGTGTGGTTCCAGTTCTTGGTGGAGGTCAAGAGGGTTTGCAGCTGCAGAGGCAAGGCTCGTTGACTCTGCCTCGAACGCTTAGTCAGAAGACGGTTGATCAAGTTTGGAAAGATCTATCCAAAGTTGGAAGTAGTGGAGTAGGGGGAAGTAACTTGTCTCAGGTGGCTCAGGCTCAGAGTCAGAGTCAGAGTCAGAGGCAGCAAACATTAGGTGAAGTAACTTTGGAGGAGTTTTTGGTTCGTGCTGGTGTTGTGAGAGAGGAAGCTCAGGTTGCTGCAAGAGCTCAGATTGCTGAGAACAATAAAGGCGGTTACTTTGGTAATGATGCCAACACAGGTTTCTCTGTCGAGTTTCAGCAGCCTTCTCCACGAGTTGTTGCCGCTGGTGTAATGGGAAATCTTGGTGCAGAGACTGCAAATTCTTTGCAGGTTCAAGGTTCTAGTTTGCCTCTGAATGTGAATGGAGCTAGAACAACATACCAGCAATCGCAACAGCAACAGCCAATCATGCCTAAGCAGCCTGGTTTTGGTTATGGAACACAAATGGGTCAGCTTAATAGTCCTGGGATAAGAGGTGGTGGTCTTGTGGGACTTGGAGATCAGTCTTTAACGAACAATGTGGGCTTTGTCCAAGGTGCTTCTGCTGCAATTCCTGGAGCTTTAGGCGTTGGTGCTGTGTCGCCTGTTACGCCATTGTCATCAGAAGGGATAGGGAAGAGTAATGGTGATTCTTCATCACTCTCTCCGTCTCCTTACATGTTTAATGGTGGTGTGAGAGGTAGAAAGAGTGGCACTGTGGAGAAAGTTGTAGAGAGAAGGCAAAGGAGAATGATAAAGAACCGAGAATCAGCTGCAAGGTCCCGGGCCAGGAAACAGGTTAATCTCTTCATCACCATCTATCTATGTACTCTTGATTGTGTTATAAGCCAAAAGATATGTAAAGTAAATTGGTTAGCTTATCTTGTAGTTAAGTTCTTTAACCACAATGAAGCGTTGAATTCAAAGCGTAAAGTGTCTTGTGTGAAGTAG
Protein Sequence:
  • >AT1G45249.2|Arabidopsis_thaliana|bZIP|AT1G45249.2
    MDGSMNLGNEPPGDGGGGGGLTRQGSIYSLTFDEFQSSVGKDFGSMNMDELLKNIWSAEETQAMASGVVPVLGGGQEGLQLQRQGSLTLPRTLSQKTVDQVWKDLSKVGSSGVGGSNLSQVAQAQSQSQSQRQQTLGEVTLEEFLVRAGVVREEAQVAARAQIAENNKGGYFGNDANTGFSVEFQQPSPRVVAAGVMGNLGAETANSLQVQGSSLPLNVNGARTTYQQSQQQQPIMPKQPGFGYGTQMGQLNSPGIRGGGLVGLGDQSLTNNVGFVQGASAAIPGALGVGAVSPVTPLSSEGIGKSNGDSSSLSPSPYMFNGGVRGRKSGTVEKVVERRQRRMIKNRESAARSRARKQVNLFITIYLCTLDCVISQKICKVNWLAYLVVKFFNHNEALNSKRKVSCVK