Gene Details:
- Gene ID: Araip.I5D0R
- Gene Family: bZIP Family
- Description: bZIP Family protein
- Species: Arachis ipaensis
- Source: bZIP family gene from PlantTFDB
Protein Features:
- SMART: SM00338
- Gene3D: G3DSA:1.20.5.170
- PROSITE profile: PS50217
- Pfam: PF00170
- SuperFamily: SSF57959
- PROSITE pattern: PS00036
- InterPro: IPR004827
Annotation Proteins:
- Refseq: XP_016201827.1 — G-box-binding factor 1
- Refseq: XP_016201828.1 — G-box-binding factor 1
- Refseq: XP_016201829.1 — G-box-binding factor 1
- Refseq: XP_020978659.1 — G-box-binding factor 1
- Refseq: XP_020978660.1 — G-box-binding factor 1
- Refseq: XP_025653079.1 — G-box-binding factor 1-like
- Refseq: XP_025653080.1 — G-box-binding factor 1-like
- Refseq: XP_025653081.1 — G-box-binding factor 1-like
- Refseq: XP_025653082.1 — G-box-binding factor 1-like
- Refseq: XP_025653083.1 — G-box-binding factor 1-like
- Refseq: XP_025653084.1 — G-box-binding factor 1-like
- Refseq: XP_025653085.1 — G-box-binding factor 1-like
- Swissprot: P42774 — GBF1_ARATH; G-box-binding factor 1
- TrEMBL: A0A444Z9R6 — A0A444Z9R6_ARAHY; Uncharacterized protein
- STRING: GLYMA11G06960.2 — (Glycine max)
Gene Ontology:
- GO:0006355 — Biological Process — regulation of transcription, DNA-templated
- GO:0010310 — Biological Process — regulation of hydrogen peroxide metabolic process
- GO:0010629 — Biological Process — negative regulation of gene expression
- GO:0090342 — Biological Process — regulation of cell aging
- GO:0005737 — Cellular Component — cytoplasm
- GO:0003700 — Molecular Function — transcription factor activity, sequence-specific DNA binding
- GO:0043565 — Molecular Function — sequence-specific DNA binding
- GO:0044212 — Molecular Function — transcription regulatory region DNA binding
Family Introduction:
- The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
- Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.
Literature:
Sequences:
CDS Sequence:
- >Araip.I5D0R|Arachis_ipaensis|bZIP|Araip.I5D0R
ATGGGGACTGGGGAAGAAAGCACAGCTAAACCTTCTAAACCATCGTCTACAACTCAGGAGATTGCACCGGTTCCTTCCTATCCTGATTGGTCAAGCTCTATGCAGGCTTATTATGCCCCTGGAGCCACTCCACCTCCTTTTTACGCCTCAACTGTTGCTTCTGCAGCTCCCCATCCCTATCTGTGGGGAGGCCAGCATCCTCTAATGCCACCATATGGTACTCCTGTTCCATATCCAGCTATATATCCTCCTGGGAGTGTCTATGCTCATCCTAGCATGGCAACGACTCCGAGTGCCCCACAGACCGAGTTTGTAGGCAAGGTACCCAACGGAAAAGATCGGAATTCTGCTAAAAATTTGAAGGGAACTTCTGCCAATAATGGTTCTAAAGCAGGAGAAAATGGAAAGGCAGGTTCAGGGTCAGGAAATGATGCAGTCTCACAAAGTGGTGAAAGCGGTTCTGAGGGATCATCCGATGACAGTGATGAGAATGCTAACCATCAGGAATCGGCTACAAACAAGAAAGGAAGCTTTGACAAAATGCTTGCTGATGGAGCCAATGCACAGAACAATGCCATAACTCAATCTTCTGGAAAGGCTGCTGTGTCAATGGCTGCAACTAATCTCAATATTGGAATGGACTTGTGGAATGCATCTTCTGCAGGTGCTGATGCTACAAAACTGAGAAACAATCAACCTGCCCCAGGAGCTGTCAACCCTCCTACTATAATGGGACGTGAAGTTGCACTTGGTGAACAGTGGATACAAGACGAACGTGAGCTGAAGAGACAGAAAAGAAAACAGTCTAACAGAGAATCAGCTAGGAGGTCAAGACTACGCAAGCAGGCTGAGTGTGAGGAGTTGCAAAAGAAGGTCGAGTCACTGGGAAACGAGAACCGGACTCTGAGAGAAGAACTTCAGAGAGTATCAGAAGAATGCGAGAAGCTTACAGCTGAAAATAATTCCATCAAGGAAGAGTTGGAAAGGTTATGTGGACCAGAAGCAGTTGCCAGCCTCGAATAA
Protein Sequence:
- >Araip.I5D0R|Arachis_ipaensis|bZIP|Araip.I5D0R
MGTGEESTAKPSKPSSTTQEIAPVPSYPDWSSSMQAYYAPGATPPPFYASTVASAAPHPYLWGGQHPLMPPYGTPVPYPAIYPPGSVYAHPSMATTPSAPQTEFVGKVPNGKDRNSAKNLKGTSANNGSKAGENGKAGSGSGNDAVSQSGESGSEGSSDDSDENANHQESATNKKGSFDKMLADGANAQNNAITQSSGKAAVSMAATNLNIGMDLWNASSAGADATKLRNNQPAPGAVNPPTIMGREVALGEQWIQDERELKRQKRKQSNRESARRSRLRKQAECEELQKKVESLGNENRTLREELQRVSEECEKLTAENNSIKEELERLCGPEAVASLE