Gene Details:
- Gene ID: Araha.3864s0011.1.p
- Gene Family: bZIP Family
- Description: bZIP Family protein
- Species: Arabidopsis halleri
- Source: bZIP family gene from PlantTFDB
Protein Features:
- SMART: SM00338
- Gene3D: G3DSA:1.20.5.170
- PROSITE profile: PS50217
- Pfam: PF00170
- SuperFamily: SSF57959
- PROSITE pattern: PS00036
- InterPro: IPR004827
Annotation Proteins:
- Refseq: XP_002880229.1 — G-box-binding factor 3 isoform X1
- Swissprot: P42776 — GBF3_ARATH; G-box-binding factor 3
- TrEMBL: D7LDY1 — D7LDY1_ARALL; G-box binding factor 3
- STRING: fgenesh1_pm.C_scaffold_4002338 — (Arabidopsis lyrata)
Gene Ontology:
- GO:0006355 — Biological Process — regulation of transcription, DNA-templated
- GO:0009737 — Biological Process — response to abscisic acid
- GO:0005829 — Cellular Component — cytosol
- GO:0003700 — Molecular Function — transcription factor activity, sequence-specific DNA binding
- GO:0043565 — Molecular Function — sequence-specific DNA binding
- GO:0044212 — Molecular Function — transcription regulatory region DNA binding
Family Introduction:
- The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
- Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.
Literature:
Sequences:
CDS Sequence:
- >Araha.3864s0011.1.p|Arabidopsis_halleri|bZIP|Araha.3864s0011.1.p
ATGGGAAATAGCAGCGAGGAACCAAAGCCTACCAAATCAGAGAAACCTTCTTCAACTCCGGTGGATCAAACAAATGTTCATGTGTACCCTGATTGGGCAGCTATGCAGGCATATTATGGTCCAAGAGTTGCAATGCCTCCTTATTACAATTCAGCTTTGGCTGCATCTGGTCATCCTCCTCCTCCTTACATGTGGAATCCTCAGCATATGATGTCACCATATGGAGCACCCTATGCTGCGGTTTATCCTCATGGAGGAGGAGTTTACGCTCATCCCGGAATTCCCATGGGATCACAGCCTCAAGGTCAAAAGGCTCCACCTTTAACAACTCCGGGGACGCATTTGAGCATCGACACTCCTACTAAATCTACAGGGAACACAGACAATGGATTGATGAAGAAGCTGAAAGAGTTTGATGGGCTTGCTATGTCTCTAGGAAATGGAAATCCTGAAAGTGGTGCAGAGGAACATAAACGATCACGGAACAGCTCAGAAACTGATGGTTCAACGGATGGAAGTGATGGGAATACAACTGGGGCAGATGAACCGAAACTTAAAAGAAGTCGAGAGGGAACACCAACAAAAGATGGTGATACCGGCGTAAAACTTATTCAAGGATCAGCAATACTCTCTCCTGGTGTAAGTGCAAATTCCAACCCCTTCATGTCACAATCTTTAGCCATGGTTCCTCCTGAAACTTGGCCTCAGAACGAGAGAGAACTGAAACGGGAGCGAAGGAAACAGTCTAATAGAGAATCTGCTAGAAGGTCAAGATTAAGAAAACAGGCCGAGACGGAAGAACTTGCTAGGAAAGTCGAAGCCTTGACAGCCGAAAACATGGCACTAAGATCTGAACTAAACCAACTTAATGAGAAATCGGATAAACTAAGAGGAGCAAATGCAACCTTGTTGGACAAACTGAAATGCTCAGAACCTGAAAAGAGAGTCTGCGGGAATATGTTGTCTAGAGTTAAAAACTCAGGAGCTGGAGACAAGAACAAGAACCAAGGAGACAATGATTCTAACTCTACAAGCAAATTGCATCAACTGCTGGATACGAAGCCCCGAGCAAATGCTGTAGCTGCGGGCTAA
Protein Sequence:
- >Araha.3864s0011.1.p|Arabidopsis_halleri|bZIP|Araha.3864s0011.1.p
MGNSSEEPKPTKSEKPSSTPVDQTNVHVYPDWAAMQAYYGPRVAMPPYYNSALAASGHPPPPYMWNPQHMMSPYGAPYAAVYPHGGGVYAHPGIPMGSQPQGQKAPPLTTPGTHLSIDTPTKSTGNTDNGLMKKLKEFDGLAMSLGNGNPESGAEEHKRSRNSSETDGSTDGSDGNTTGADEPKLKRSREGTPTKDGDTGVKLIQGSAILSPGVSANSNPFMSQSLAMVPPETWPQNERELKRERRKQSNRESARRSRLRKQAETEELARKVEALTAENMALRSELNQLNEKSDKLRGANATLLDKLKCSEPEKRVCGNMLSRVKNSGAGDKNKNQGDNDSNSTSKLHQLLDTKPRANAVAAG*