Gene Details:
- Gene ID: Aco013098.1
- Gene Family: bZIP Family
- Description: bZIP Family protein
- Species: Ananas comosus
- Source: bZIP family gene from PlantTFDB
Protein Features:
- SMART: SM00338
- Gene3D: G3DSA:1.20.5.170
- PROSITE profile: PS50217
- Pfam: PF00170
- SuperFamily: SSF57959
- PROSITE pattern: PS00036
- InterPro: IPR004827
Annotation Proteins:
- Refseq: XP_020079647.1 — basic leucine zipper 19-like
- Refseq: XP_020079648.1 — basic leucine zipper 19-like
- Refseq: XP_020079649.1 — basic leucine zipper 19-like
- Refseq: XP_020079650.1 — basic leucine zipper 19-like
- Swissprot: Q8VY76 — BZP19_ARATH; Basic leucine zipper 19
- TrEMBL: A0A199VL22 — A0A199VL22_ANACO; Uncharacterized protein
- STRING: GSMUA_Achr3P00670_001 — (Musa acuminata)
Gene Ontology:
- GO:0006355 — Biological Process — regulation of transcription, DNA-templated
- GO:0003700 — Molecular Function — transcription factor activity, sequence-specific DNA binding
- GO:0043565 — Molecular Function — sequence-specific DNA binding
Family Introduction:
- The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
- Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.
Literature:
Sequences:
CDS Sequence:
- >Aco013098.1|Ananas_comosus|bZIP|Aco013098.1
ATGGAGGAAAACATAGGCTTCTCTGAATCGGATATGTTCTCGACACCCATTAATGGCGAAGACCCCCTCCTTAGCTGCTCCATGGATAGCATCTTCGATGAGATCCTCAAAGACACCCACCACCACGTGTGCACCCACACCCACACGTGCAATCCCCCGGCCCCCGGCCCTGACCTCTCGCACACGCACACGTGCTTCCACGTGCACACGAAGATCCTGTCGGCGCCCGCTGATCGATCGGCTGAGTCCGCCGAGAAGAGCTCGTGTCCAAAGAAGCGGCTTCGCGGTAACAGGGATGCGGTGAAGAAGTACCGGGAGAAGAAGAAGGCGCACGCCGCCTCTTTAGAGGAGGAGGCGGCCAAATTGAGGGCTTTGAATCAGCAGCTGATGAATCGGCTTCAGGGAGAAGCTGCGCTGGTGGCGGAAGCAGCGAGGCTTCGGTGCTTGCTCGTCGACATACGAGGAAGGATCGAAGGAGAGATTGGGTCGTTCCCGTACCAGAAGCCGATGAGGCGGGGCGGAGAATTGGTCTCTATGCACTTTGTGAGCCCTTGCGATTTCTGCTGCGACGATCAAGCGTACTGCGGTTATCCGGGGATGCGTCTGAAAAATATCGAGGGAAGTGATGTGACGATGGATGGTCGGGGATCGGGAGTTTGCGATGTTGGGAGTGGTCGATGCAGGGGGAGTCCAAGTTCCGGATCGAAGAACTTGCAAAAGGAAAAGGTGTCCGTCGATGGTCGATCTGCTGTTGACGACAAGCTGATTTCGTTGCTTGCATCATCTCCTGAAGATATTCGTCGAACATCAACAGTGTTTCATCTGTCTCTTAGTTTGTTCATTTAA
Protein Sequence:
- >Aco013098.1|Ananas_comosus|bZIP|Aco013098.1
MEENIGFSESDMFSTPINGEDPLLSCSMDSIFDEILKDTHHHVCTHTHTCNPPAPGPDLSHTHTCFHVHTKILSAPADRSAESAEKSSCPKKRLRGNRDAVKKYREKKKAHAASLEEEAAKLRALNQQLMNRLQGEAALVAEAARLRCLLVDIRGRIEGEIGSFPYQKPMRRGGELVSMHFVSPCDFCCDDQAYCGYPGMRLKNIEGSDVTMDGRGSGVCDVGSGRCRGSPSSGSKNLQKEKVSVDGRSAVDDKLISLLASSPEDIRRTSTVFHLSLSLFI*