Gene Details:
- Gene ID: AA30G00112
- Gene Family: bZIP Family
- Description: bZIP Family protein
- Species: Aethionema arabicum
- Source: bZIP family gene from PlantTFDB
Protein Features:
- SMART: SM00338
- Gene3D: G3DSA:1.20.5.170
- PROSITE profile: PS50217
- Pfam: PF00170
- SuperFamily: SSF57959
- PROSITE pattern: PS00036
- InterPro: IPR004827
Annotation Proteins:
- Refseq: XP_010437402.1 — PREDICTED: protein FD-like isoform X1
- Swissprot: Q84JK2 — FD_ARATH; Protein FD
- TrEMBL: A0A1J3HBH2 — A0A1J3HBH2_NOCCA; Protein FD (Fragment)
- TrEMBL: A0A1J3J4V9 — A0A1J3J4V9_NOCCA; Protein FD (Fragment)
- STRING: XP_010437402.1 — (Camelina sativa)
Gene Ontology:
- GO:0009911 — Biological Process — positive regulation of flower development
- GO:0045893 — Biological Process — positive regulation of transcription, DNA-templated
- GO:2000028 — Biological Process — regulation of photoperiodism, flowering
- GO:0005634 — Cellular Component — nucleus
- GO:0003700 — Molecular Function — transcription factor activity, sequence-specific DNA binding
- GO:0043565 — Molecular Function — sequence-specific DNA binding
- GO:0043621 — Molecular Function — protein self-association
Family Introduction:
- The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
- Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.
Literature:
Sequences:
CDS Sequence:
- >AA30G00112|Aethionema_arabicum|bZIP|AA30G00112
ATGTTGTCATCAACAGAGCTTCAAGTAAACCACAAAATCTCTGATTCCAATAAGAACAACACTCTAAACCGAGTTTCTTCCATTTCACCATCATCATCATCATCTTCATCATCATCATCATCATCGACATCATCTTCTTCATCATCTCCTTTGCTAAAGTCACAAGACTGTCAAATCCAGAACAACAGATCTTTAAACACCATGGAAGAAGTTTGGAAAGACATCAATCTTGCTTCTCTTCATCACCTAAACCGCAACACTCAACATCCACAACATATTCATGACCCAAGATTCAGGAGCCATCACCAGAATCAAAACCCTAACTCTATTTTTCAAGATTTTCTCAACAGACCTTTGAATCACGAGATACCTACGAGCTTGAGCATGGCTTCTGCTTCTAATGGTGATACAAGCACTGTCACTGCTCTTTACACCGCTCCTATCCCACCTCCTGCAACTGTTCTGAGCTTGAATTCCGGTGCTGGCTTTGAATTTCTTGATAACCCAGATCCACTTGTTACTCCAAACTCTCATTTACAGAGCCAACGTCATCTCTCAAATGTCTCTTCTTTTGACACCCCTTTTGAAGCTCTGGTTACATATGCAAGGCTTGGTTGTTTTAGTAAGAAAAGAGGTCAAGACTCTGATGAAAGTTCAGGGAATAGAAGACATAAGCGTATGATCAAGAACAGAGAGTCTGCAGCTCGTTCCAGAGCTAGGAAACAGGAATGCTTATACAAACGAGTTAGAGCT
Protein Sequence:
- >AA30G00112|Aethionema_arabicum|bZIP|AA30G00112
MLSSTELQVNHKISDSNKNNTLNRVSSISPSSSSSSSSSSSSTSSSSSSPLLKSQDCQIQNNRSLNTMEEVWKDINLASLHHLNRNTQHPQHIHDPRFRSHHQNQNPNSIFQDFLNRPLNHEIPTSLSMASASNGDTSTVTALYTAPIPPPATVLSLNSGAGFEFLDNPDPLVTPNSHLQSQRHLSNVSSFDTPFEALVTYARLGCFSKKRGQDSDESSGNRRHKRMIKNRESAARSRARKQECLYKRVRA