Information report for 478415
Gene Details
Functional Annotation
- Refseq: XP_002882698.1 — bZIP transcription factor 28 isoform X1
- Swissprot: Q9SG86 — BZP28_ARATH; bZIP transcription factor 28
- TrEMBL: D7L9R1 — D7L9R1_ARALL; BZIP transcription factor family protein
- STRING: fgenesh2_kg.3__1116__AT3G10800.1 — (Arabidopsis lyrata)
- GO:0006990 — Biological Process — positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
- GO:0009408 — Biological Process — response to heat
- GO:0005635 — Cellular Component — nuclear envelope
- GO:0005654 — Cellular Component — nucleoplasm
- GO:0005783 — Cellular Component — endoplasmic reticulum
- GO:0016021 — Cellular Component — integral component of membrane
- GO:0048471 — Cellular Component — perinuclear region of cytoplasm
- GO:0003700 — Molecular Function — transcription factor activity, sequence-specific DNA binding
- GO:0043565 — Molecular Function — sequence-specific DNA binding
Family Introduction
- The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.
- Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.
Literature and News
Gene Resources
Homologs
- Arabidopsis thaliana: AT3G10800.1, AT3G10800
- Brassica napus: GSBRNA2T00061319001, GSBRNA2T00060242001
- Brassica oleracea: XP_013635480.1
- Brassica rapa: XP_009122597.1, XP_009114935.1
- Cucumis melo: MELO3C009730P1
- Cucumis sativus: Cucsa.337510.1
- Gossypium arboreum: Cotton_A_20550_BGI-A2_v1.0
- Gossypium hirsutum: Gh_D13G0009, Gh_A13G2071
- Juglans regia: WALNUT_00017669-RA
- Vitis vinifera: GSVIVT01025788001
Sequences
CDS Sequence:
- >478415|Arabidopsis_lyrata|bZIP|478415
ATGACGGAATCAACATTCGTTATTGCTCCTCCGCCGGAGATACCTAATCTGAACCCTAGCATGTTTTCGGAATCCGATATGATTTCTATTCCGCCGCTAGATCCTCTTTTCCTATCTGATTCTGATCCGATTTCAATGGATGCGCCGATCTCCGATCTCGACTTCTTACTCGACGATGAGAACGGAGATTTTGCTGATTTCGATTTCTCGTTTGAGAATTCTGATGATTTCTTCGATTTCGATTTGGCGGAGCCCGCGGTGGTGATCCCTGAGGAGATCGGGAATAGTCGTTCGAATTTGGACTCATCGGAGAACAGAAGCGGCGATGGAGGTTTAGAAGGACGATCTGATTCTGTTCATTCTCAGGTTTCATCTCAAGGCTCAAAGACTTTTGTGTCCGACACCGTTGACGCATTATCCTCCCCTGAATCAAGCAATCACCAGAAATCTTCTGTCAGCAAGAGGAAGAATGAAAATGGAGACTCCAGTGGCGAATTAAGGAGCTGCAAGTACCAAAAGTCTGATGATAAATCAGTCGCTACGAACAACGAAGGTGATGATGACGACAAGAGGAAGTTGATAAGGCAGATTAGGAACCGTGAAAGTGCTCAGCTTTCGAGGTTGAGGAAGAAGCAACAAACTGAGGAGCTTGAAAGAAAAGTGAAGAGTATGAATGCCACCATTGCTGAATTGAATGGTAAGATTGCTTATGTTATGGCTGAGAATGTAGCTTTAAGGCAACAAATGGCTGTTGCTTCTGGTGCGCCTCCTATGAATCCTTATATGGCTGCACCGCCTTTACCGTATCAATGGATGCCCTATCCGCCTTATCCTGTTAGGGGCTATGGATCACAGACTCCATTGGTTCCCATTCCCAAGTTAAATCCTAAGCCTGTCTCGAGTTGTAGACCGAAGAAGGCAGATAGTAAGAAGAATGAGGGCAAAAGTAAGCTCAAGAAGGTTGCTAGTATTAGTTTTATTGGAATTCTCTTCTTTATGTTCTTGTTTGGTACATTGGTTCCGTTTATGAATGTAAATTATGGAGGAGAAGGTGGAAGCTTTGGCGGTTTGTCTAAATATGATGGTCACCGGTATTACGATGAACATAAGGGGAAGGTTCTAATGGTCGGGGATGGTTCTGATGTTAGAAGAGAAAGTGGGATTTCTGAAGGAAATATACATTCTAGTAGGATAATTCATGGTGAGAGAGATAGTTGTGGAGGAGTAGATTATAATGGTCATCCGAAAGTAGAAGGACGATCAAGTTCATTGAGCAATGCGAGTGATCCTCTGTTTGCTTCACTCTATGTCCCAAGAAACGATGGGCTTGTGAAGATCGATGGGAACTTGATAATTCACTCTGTTTTGGCGAGCGAGAAAGCAACGGCTCTAGGGAAGAAGAATATCACTGAAACAGTCAAAAGTAAAGAACCGGATTTGACCATGCCTGGTGCACTGTCTTCTGCTATAGCTGTTCCGGAGGTAAGAGGAAATGCAGCAATGCTTCCACATTCAACGGCTCTCTCTTCTGAAGGGAAAAGACTTCACCAGTGGTTTCATGAAGGTGGCTCAGGGACACTAATGGATTACAGCATGTGCACCGAGGTTTTCCAGTTTGATATTGCTCCCGGTGCGATAGTCCCATCATCAGTCTCAAACATTTCTGCGGAGCATCTCCAAAATGTCACTACCCACGGCAAGAGAATGAAGAACAGGAGAATTCTCGAGGGACTTCCTGTTTCACTTGTGGCGTCTGAGCTCAATATCACCGGAACCCAGCCGAACAAAGACGCTCAAAACAAGACCTTTCATGGAAACACTAACAAACCCACATCATCATCCTCCATGGTTGTCTCAGTGTTGCTTGATCCAAGAGAGGTCGTCGACTCTGAAAATGACAGAGTGGTGCCCCCAAACCCAAAATCACTTTCCCGGATCTTTGTGGTTGTACTTCTTGACAGTGTCAAGTACGTTACCTACTCATGCGTTCTTCCTCGGTCGGGTCTCCATCTCGTAGCCACCTGA
Protein Sequence:
- >478415|Arabidopsis_lyrata|bZIP|478415
MTESTFVIAPPPEIPNLNPSMFSESDMISIPPLDPLFLSDSDPISMDAPISDLDFLLDDENGDFADFDFSFENSDDFFDFDLAEPAVVIPEEIGNSRSNLDSSENRSGDGGLEGRSDSVHSQVSSQGSKTFVSDTVDALSSPESSNHQKSSVSKRKNENGDSSGELRSCKYQKSDDKSVATNNEGDDDDKRKLIRQIRNRESAQLSRLRKKQQTEELERKVKSMNATIAELNGKIAYVMAENVALRQQMAVASGAPPMNPYMAAPPLPYQWMPYPPYPVRGYGSQTPLVPIPKLNPKPVSSCRPKKADSKKNEGKSKLKKVASISFIGILFFMFLFGTLVPFMNVNYGGEGGSFGGLSKYDGHRYYDEHKGKVLMVGDGSDVRRESGISEGNIHSSRIIHGERDSCGGVDYNGHPKVEGRSSSLSNASDPLFASLYVPRNDGLVKIDGNLIIHSVLASEKATALGKKNITETVKSKEPDLTMPGALSSAIAVPEVRGNAAMLPHSTALSSEGKRLHQWFHEGGSGTLMDYSMCTEVFQFDIAPGAIVPSSVSNISAEHLQNVTTHGKRMKNRRILEGLPVSLVASELNITGTQPNKDAQNKTFHGNTNKPTSSSSMVVSVLLDPREVVDSENDRVVPPNPKSLSRIFVVVLLDSVKYVTYSCVLPRSGLHLVAT*