Gene Details:

  • Gene ID: GSBRNA2T00136887001
  • Gene Name: GSBRNA2T00136887001
  • Gene Family: BES1 Family
  • Description: BES1 Family protein
  • Species: Brassica napus
  • Source: BES1 family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  XP_013600035.1  — PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
  • Refseq:  XP_013600036.1  — PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
  • Refseq:  XP_013600037.1  — PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
  • Refseq:  XP_013664433.1  — protein BRASSINAZOLE-RESISTANT 2-like
  • Refseq:  XP_013664434.1  — protein BRASSINAZOLE-RESISTANT 2-like
  • Swissprot:  Q9LN63  — BZR2_ARATH; Protein BRASSINAZOLE-RESISTANT 2
  • TrEMBL:  A0A0D3DWH6  — A0A0D3DWH6_BRAOL; Uncharacterized protein
  • TrEMBL:  A0A3P6GPZ9  — A0A3P6GPZ9_BRAOL; Uncharacterized protein
  • STRING:  Bo8g102770.1  — (Brassica oleracea)

Gene Ontology:

  • GO:0006355  — Biological Process — regulation of transcription, DNA-templated

Family Introduction:

  • Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1(BRI1-EMS-SUPPRESSOR 1), accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo.
  • BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.

Literature:

Sequences:

CDS Sequence:
  • >GSBRNA2T00136887001|Brassica_napus|BES1|GSBRNA2T00136887001
    ATGACGTCTGAGGGAGCGATGTTGACGTCCGCAGCATCGATGGCGACGAGACGGAAGCCGTCGTGGAGAGAGAGGGAGAACAATAGGAGGAGGGAGAGGAAAAGAAGAGCTGTAGCGGCGAAGATTTATAACGGTCTCAGAGTTCAAGGTAACTTCAATCTTCCCAGGCATTGTGACAACAATGAAGTGCTTAAAGCTCTGTGTTCCGAAGCTGGTTGGGTGGTCGAAGAGGACGGAACCACTTATCGCAAGGGACATAAGCCTCTTCCTGATGACATGGCTGGATCATCTTCTCGTGCCACTCCTTACTCTTCTTATAACCAAAGTCCTTTTGAAAGTCCCATACTTTCTTACCAAGTCAGCCCGTCATCTTCTGCATTCCCGAGCCCTTCTCGTAGTGGCGACACACACAACATCTCCACCATCTTCCCTTTCCTCAGGAACGGTGGGATTAATCCTTCATCGCTTCCTCCACTTAGAATCTCAAACAGTGCTCCTGTCACTCCACCTGTCTCATCCCCACCTTCTAGAAACCCTAAGCCATTACCCACTTGGGAGTCTCTTACCAAACAGACCATGGCCAATGCTGCTAGACAATCAGTGTCATCTTTTAACTACCCGTTCTACGCTGTATCTGCACCAACGAGCCCCACTCATCATCGCCAGTTCAATGCACCGGCTACTATACCTGAATGTAATGAGTCTGACTCTTCCACTATTGATTCGGGTCATTGGATAAGCTTTCAAAAGTTCTCACAACAGCCGTTCCATGGCGGCTCTTCAGTTTCACCCTCTCCAACCTTCAATCTTGTCAAACCTCCCTTACCACAACAATTATCTCCAAACACTTCAGCAGCCCAAGAGATTGGTCAAAACAGCCAAGTTAAGCCATGGGAAGGGGAGAGGATCCATGATGTGGCTATGGAGGATCTTGAGCTCACACTTGGGAACTCTAAAGGTCGTAGCTGA
Protein Sequence:
  • >GSBRNA2T00136887001|Brassica_napus|BES1|GSBRNA2T00136887001
    MTSEGAMLTSAASMATRRKPSWRERENNRRRERKRRAVAAKIYNGLRVQGNFNLPRHCDNNEVLKALCSEAGWVVEEDGTTYRKGHKPLPDDMAGSSSRATPYSSYNQSPFESPILSYQVSPSSSAFPSPSRSGDTHNISTIFPFLRNGGINPSSLPPLRISNSAPVTPPVSSPPSRNPKPLPTWESLTKQTMANAARQSVSSFNYPFYAVSAPTSPTHHRQFNAPATIPECNESDSSTIDSGHWISFQKFSQQPFHGGSSVSPSPTFNLVKPPLPQQLSPNTSAAQEIGQNSQVKPWEGERIHDVAMEDLELTLGNSKGRS*