Gene Details:

• Gene ID: Araha.1486s0003.1.p
• Gene Family: BES1 Family
• Description: BES1 Family protein
• Species: Arabidopsis halleri
• Source: BES1 family gene from PlantTFDB

Protein Features:

• Pfam:  PF05687
• InterPro:  IPR008540

Annotation Proteins:

• Refseq:  NP_973863.1  — Brassinosteroid signaling positive regulator (BZR1) family protein
• Refseq:  XP_009117543.1  — PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
• Refseq:  XP_009117544.1  — PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
• Refseq:  XP_009117545.1  — PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
• Refseq:  XP_013664647.1  — protein BRASSINAZOLE-RESISTANT 2-like
• Refseq:  XP_020870402.1  — protein BRASSINAZOLE-RESISTANT 2
• Refseq:  XP_020870404.1  — protein BRASSINAZOLE-RESISTANT 2
• Swissprot:  Q9LN63  — BZR2_ARATH; Protein BRASSINAZOLE-RESISTANT 2
• TrEMBL:  A0A078G5C8  — A0A078G5C8_BRANA; BnaA09g44210D protein
• TrEMBL:  A0A178W3G4  — A0A178W3G4_ARATH; BZR2
• TrEMBL:  A0A397YB44  — A0A397YB44_BRACM; Uncharacterized protein
• TrEMBL:  A0A3P5Y899  — A0A3P5Y899_BRACM; Uncharacterized protein
• TrEMBL:  D7KHC7  — D7KHC7_ARALL; Bri1-ems-suppressor 1
• TrEMBL:  F4HP45  — F4HP45_ARATH; Brassinosteroid signaling positive regulator (BZR1) family protein
• TrEMBL:  M4EQK6  — M4EQK6_BRARP; Uncharacterized protein
• STRING:  AT1G19350.3  — (Arabidopsis thaliana)
• STRING:  Bra031077.1-P  — (Brassica rapa)
• STRING:  fgenesh2_kg.1__2112__AT1G19350.4  — (Arabidopsis lyrata)
• STRING:  Bostr.7128s0539.1.p  — (Boechera stricta)

Family Introduction:

• Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1(BRI1-EMS-SUPPRESSOR 1), accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo.
• BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.

Literature:

• A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis.   DOI:  10.1016/j.cell.2004.11.044 ;  PMID:  15680330

Sequences: