Gene Details:

  • Gene ID: Aradu.S93F6
  • Gene Family: BES1 Family
  • Description: BES1 Family protein
  • Species: Arachis duranensis
  • Source: BES1 family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  XP_016702634.1  — PREDICTED: BES1/BZR1 homolog protein 4-like isoform X1
  • Refseq:  XP_016702636.1  — PREDICTED: BES1/BZR1 homolog protein 4-like isoform X2
  • Swissprot:  Q5Z9E5  — BZR3_ORYSJ; Protein BZR1 homolog 3
  • TrEMBL:  A0A1U8KJC4  — A0A1U8KJC4_GOSHI; BES1/BZR1 homolog protein 4-like isoform X1
  • TrEMBL:  A0A2P5WYB4  — A0A2P5WYB4_GOSBA; Uncharacterized protein
  • STRING:  XP_010675300.1  — (Beta vulgaris)
  • STRING:  XP_009352718.1  — (Pyrus x bretschneideri)

Family Introduction:

  • Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1(BRI1-EMS-SUPPRESSOR 1), accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo.
  • BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.

Literature:

Sequences:

CDS Sequence:
  • >Aradu.S93F6|Arachis_duranensis|BES1|Aradu.S93F6
    ATGACTTCAGGAACTCGGCTTCCGACATGGAAGGAGAGAGAGAACAACAAGAGGAGAGAGAGGAGGAGAAGAGCAATAGCGGCAAAGATCTTCGCCGGTCTAAGAATGTACGGAAACTTCAAGCTCCCAAAGCACTGTGACAACAACGAAGTCCTCAAAGCTCTTTGCAATGAAGCTGGTTGGACCGTTGAACCAGATGGCACCACTTACCGCAAGGTAACCAACTAACTAACTTAGTAACCGTTGAAGAGAGTGCCTGTCATTTTATTTTACTTAATTGGAATAATGGTGTCTTAG
Protein Sequence:
  • >Aradu.S93F6|Arachis_duranensis|BES1|Aradu.S93F6
    MTSGTRLPTWKERENNKRRERRRRAIAAKIFAGLRMYGNFKLPKHCDNNEVLKALCNEAGWTVEPDGTTYRKVTNLTPLKRVPVILFYLIGIMVS